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anti-Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1) Antibodies

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. Additionally we are shipping Solute Carrier Family 22 (Organic Cation Transporter), Member 1 Kits (4) and Solute Carrier Family 22 (Organic Cation Transporter), Member 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC22A1 6580 O15245
SLC22A1 20517 O08966
SLC22A1 24904 Q63089
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Top anti-Solute Carrier Family 22 (Organic Cation Transporter), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-SLC22A1 Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-SLC22A1 Antibody Titration: 5.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Flow cytometric analysis of Jurkat cells using SLC22A1 mouse mAb (green) and negative control (purple) . Figure 2: Western blot analysis using SLC22A1 mAb against HEK293 (1) and SLC22A1 (AA: 284-347) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated WB Anti-SLC22A1 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: A549 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB SLC22A1 Antibody (C-term) (ABIN657865) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the SLC22A1 antibody detected the SLC22A1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using OCT1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using OCT1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Hela xenograft, using OCT1, antibody at 1:750 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

SLC22A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Solute Carrier Family 22 (Organic Cation Transporter), Member 1 Antibodies

  1. Human Monoclonal SLC22A1 Primary Antibody for EIA, FACS - ABIN1109041 : Zach, Krieger, Foedermayr, Zellhofer, Lutz: OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients. in Leukemia & lymphoma 2008 (PubMed)
    Show all 3 references for ABIN1109041

  2. Human Monoclonal SLC22A1 Primary Antibody for FACS, ELISA - ABIN969400 : Hirayama, Watanabe, Nakashima, Nanbu, Hamada, Kuniyasu, Nakayama, Kawaguchi, Saito: Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells. in Pharmaceutical research 2008 (PubMed)
    Show all 3 references for ABIN969400

  3. Human Polyclonal SLC22A1 Primary Antibody for IHC, WB - ABIN2776916 : Bourdet, Pritchard, Thakker: Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3). in The Journal of pharmacology and experimental therapeutics 2005 (PubMed)
    Show all 2 references for ABIN2776916

More Antibodies against Solute Carrier Family 22 (Organic Cation Transporter), Member 1 Interaction Partners

Human Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1) interaction partners

  1. This study indicates a promising role for intratumoral OCT1 (show POU2F1 Antibodies) mRNA expression as a prognostic biomarker in therapeutic algorithms in HCC (show FAM126A Antibodies)

  2. Data show that bisindolylmaleimides (BIMs) Ro 31-8220 also blocks activity of the solute carrier (show SERTAD2 Antibodies) organic cation transporter 1 (OCT1), involved in uptake of marketed drugs in the liver, in a protein kinase C (PKC (show PKC Antibodies))-independent manner.

  3. Homozygous carriers of the polymorphic OCT1 (show POU2F1 Antibodies) C-allele had no metformin-related toxicity as compared with 41.9% for any metformin-related toxicity in carriers of at least one wild-type A-allele

  4. A positive association was observed between the expression of the ABCB1 (show ABCB1 Antibodies) and ABCG2 (show ABCG2 Antibodies) transporter genes (r=0.407, P<0.05) while no association was observed between the expression of either of the ABC transporter (show ABCG2 Antibodies) genes with the OCT1 (show POU2F1 Antibodies) gene

  5. Data indicate no association was found between genotypes of drug transporters ABCB1 (show ABCB1 Antibodies), ABCG2 (show ABCG2 Antibodies), OCT1 (show POU2F1 Antibodies) genetic polymorphisms and the occurrence of thrombocytopenia.

  6. Findings suggest specific involvement of each organic cation transporters (OCT1 (show POU2F1 Antibodies)-3) in drug transportation.

  7. Our data suggest that besides bodyweight, OCT1 (show POU2F1 Antibodies) and ABCC3 (show ABCC3 Antibodies) genotypes play a significant role in the pharmacokinetics of intravenous morphine and its metabolites in children

  8. Nucleoside transporters and human OCT1 (show POU2F1 Antibodies) determine the cellular handling of DNA-methyltransferase (show DNMT1 Antibodies) inhibitors

  9. The hOCT1 expression level can be an important predictor in CML patients treated with IM.

  10. OCT1 (show POU2F1 Antibodies) plays a significant role in hepatic elimination of serotonin at the transporter level.

Cow (Bovine) Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1) interaction partners

  1. Dopamine transport across the olfactory and respiratory mucosae is partially mediated by organic cation transporters, including OCT-1 (show POU2F1 Antibodies) and OCT-2 (show SLC22A2 Antibodies).

Mouse (Murine) Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1) interaction partners

  1. Data indicate that the expression of the organic cation transporters Slc22a1, Slc22a2 (show SLC22A2 Antibodies) and Slc22a3 (show OCT3 Antibodies) essential for the cellular uptake of metformin was highly suppressed in Tsc1 (show TSC1 Antibodies)+/-renal tumours.

  2. Transcripts encoding OCT1-3 and ChAT (choline acetyltransferase) have been detected in tracheal epithelial cells; these data suggest that cells lining the airway are able to synthesize/secrete acetylcholine into the lumen.

  3. The influence of organic cation transporters 1, 2, and 3 (OCT1 (show POU2F1 Antibodies), OCT2 (show SLC22A2 Antibodies), and OCT3 (show POU5F1 Antibodies)) and their genetic variants on cellular uptake of picoplatin and on the individual components of the ensuing cytotoxicity such as DNA adduct formation, was determined.

  4. Oct1 (show POU2F1 Antibodies) forms repeating, cyclosporin-sensitive regulatory modules within the CD21 (show CR2 Antibodies) intronic control region.

  5. a comparison of the transport properties of Oct2 (show SLC22A2 Antibodies) and Oct1 (show POU2F1 Antibodies)

  6. oct1 (show POU2F1 Antibodies) has a role in controlling fgl2 (show FGL2 Antibodies) expression in endothelial cells

  7. This study shows that Oct1 (show POU2F1 Antibodies) and Oct2 (show SLC22A2 Antibodies) together are essential for renal secretion of (small) organic cations.

  8. nuclear factor Y and Oct-1 bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated expression of the mGnRH receptor gene

  9. The purpose of this study was to examine the effects of peroxisome proliferator agonist receptor agonists on the hepatic regulation and function of Slc22a1.

  10. a multiprotein complex containing GATA-1, Oct-1, and other protein factors may contribute to the formation of a repressive chromatin structure that silences gamma-globin gene expression

Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1) Antigen Profile

Protein Summary

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

Gene names and symbols associated with SLC22A1

  • solute carrier family 22 (organic cation transporter), member 1 (SLC22A1) antibody
  • organic cation transporter 1 (OCT1) antibody
  • renal organic cation transporter (RBOCT1) antibody
  • solute carrier family 22 (organic cation transporter), member 1 (Slc22a1) antibody
  • solute carrier family 22 member 2-like (LOC421584) antibody
  • HOCT1 antibody
  • Lx1 antibody
  • Oct1 antibody
  • oct1_cds antibody
  • Orct antibody
  • Orct1 antibody
  • Roct1 antibody
  • SLC22A1 antibody
  • SLC22A2 antibody

Protein level used designations for SLC22A1

solute carrier family 22 member 1 , solute carrier family 22 (organic cation transporter), member 1 , solute carrier family 22 member 1-like , pOCT1 , organic cation transporter 1 , mOCT1 , solute carrier family 22, member 1 , solute carrier family 22 (organic cation transporter), member 2

GENE ID SPECIES
472177 Pan troglodytes
100027984 Monodelphis domestica
100412933 Callithrix jacchus
100436901 Pongo abelii
397049 Sus scrofa
100008659 Oryctolagus cuniculus
6580 Homo sapiens
484068 Canis lupus familiaris
519461 Bos taurus
20517 Mus musculus
24904 Rattus norvegicus
421584 Gallus gallus
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