anti-Solute Carrier Family 30, Member 10 (SLC30A10) Antibodies

SLC30A10 is highly expressed in the liver and is inducible by manganese. Additionally we are shipping SLC30A10 Kits (8) and SLC30A10 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC30A10 55532 Q6XR72
SLC30A10 226781 Q3UVU3
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Top anti-SLC30A10 Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SLC30A10 Antibody [NBP1-84164] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB RNF223 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the RNF223 antibody detected the RNF223 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western Blot at 1:2000 dilution + human liver lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:2000 dilution Lane 1: human fetal brain lysate Lane 2: human fetal liver lysate Lysates/proteins at 20 ug per lane. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$594.00
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

SLC30A10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Top referenced anti-SLC30A10 Antibodies

  1. Human Polyclonal SLC30A10 Primary Antibody for IHC, IHC (p) - ABIN4354225 : Lechpammer, Clegg, Muzar, Huebner, Jin, Gospe: Pathology of inherited manganese transporter deficiency. in Annals of neurology 2014 (PubMed)

More Antibodies against SLC30A10 Interaction Partners

Human Solute Carrier Family 30, Member 10 (SLC30A10) interaction partners

  1. SLC30A10 has a protective role in 1-methyl-4-phenylpyridinium-induced toxicity via PERK (show EIF2AK3 Antibodies)-ATF4 (show ATF4 Antibodies) pathway.

  2. xpressing either wild-type or mutant forms of SLC30A10 was sufficient to inhibit the effect of ATP2C1 (show ATP2C1 Antibodies) in response to Mn challenge in both zebrafish embryos and HeLa cells. These findings suggest that either activating ATP2C1 (show ATP2C1 Antibodies) or restoring the Mn-induced trafficking of ATP2C1 (show ATP2C1 Antibodies) can reduce Mn accumulation, providing a possible target for treating HMDPC.

  3. results indicate that residues in the transmembrane and C-terminal domains together confer optimal manganese transport capability to SLC30A10 and suggest that the mechanism of ion coordination in the transmembrane domain of SLC30A10 may be substantially different from that in YiiP/other SLC30 (show SLC30A1 Antibodies) proteins.

  4. allele was also associated with increased sway velocity (15%, P = .033; adjusted for age and sex) and reduced SLC30A10 expression

  5. We describe early disease manifestations (including videos) in 5 previously unreported Indian children, carrying novel homozygous SLC30A10 mutation

  6. SLC30A10 is a cell surface-localized manganese efflux transporter that reduces manganese levels and protects against manganese toxicity.

  7. These results suggest that both the up-regulation of ZIP14 (show SLC39A14 Antibodies) and the down-regulation of ZnT10 by IL-6 (show IL6 Antibodies) might have enhanced the accumulation of manganese in SH-SY5Y cells.

  8. a case of inherited manganism caused by SLC30A10 mutation is presented

  9. ZnT10 is significantly decreased in the frontal cortex in Alzheimer's disease.

  10. This review will address Mn transport proteins, the newly discovered SLC30A10 mutations and their implications to Parkinsonism and Mn regulation.

Zebrafish Solute Carrier Family 30, Member 10 (SLC30A10) interaction partners

  1. xpressing either wild-type or mutant forms of SLC30A10 was sufficient to inhibit the effect of ATP2C1 (show ATP2C1 Antibodies) in response to Mn challenge in both zebrafish embryos and HeLa cells. These findings suggest that either activating ATP2C1 (show ATP2C1 Antibodies) or restoring the Mn-induced trafficking of ATP2C1 (show ATP2C1 Antibodies) can reduce Mn accumulation, providing a possible target for treating HMDPC.

Mouse (Murine) Solute Carrier Family 30, Member 10 (SLC30A10) interaction partners

  1. the hypothyroidism phenotype of Slc30a10 single knockouts is induced by elevated thyroid manganese, which blocks thyroxine production. These findings provide new insights into the mechanisms of manganese detoxification and manganese-induced thyroid dysfunction.

  2. SLC30A10 has a protective role in 1-methyl-4-phenylpyridinium-induced toxicity via PERK (show EIF2AK3 Antibodies)-ATF4 (show ATF4 Antibodies) pathway.

  3. discovery highlights the importance of determining the role of thyroid dysfunction in the onset and progression of manganese-induced disease and identifies Slc30a10 knock-out mice as a new model for studying thyroid biology.

SLC30A10 Antigen Profile

Protein Summary

This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with SLC30A10

  • solute carrier family 30, member 10 (SLC30A10) antibody
  • solute carrier family 30 (zinc transporter), member 10 (slc30a10) antibody
  • solute carrier family 30, member 10 (Slc30a10) antibody
  • E130106K10Rik antibody
  • Gm212 antibody
  • HMDPC antibody
  • ZnT-10 antibody
  • ZNT8 antibody
  • ZNT10 antibody
  • ZRC1 antibody

Protein level used designations for SLC30A10

zinc transporter 10 , zinc transporter 8 , solute carrier family 30, member 10 , solute carrier family 30 (zinc transporter), member 10 , ZnT10 , znT-10

GENE ID SPECIES
55532 Homo sapiens
469681 Pan troglodytes
555724 Danio rerio
226781 Mus musculus
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