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Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. Additionally we are shipping SLC38A1 Kits (5) and and many more products for this protein.
Showing 10 out of 65 products:
Human Monoclonal SLC38A1 Primary Antibody for ICC, IF - ABIN1027716
Hatanaka, Huang, Wang, Sugawara, Prasad, Leibach, Ganapathy: Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A. in Biochimica et biophysica acta 2000
Show all 7 references for 1027716
Cow (Bovine) Polyclonal SLC38A1 Primary Antibody for IHC, WB - ABIN2781566
Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ... in DNA research : an international journal for rapid publication of reports on genes and genomes 2005
SNAT1 mediated L-citrulline transport modulates eNOS (show NOS3 Antibodies) coupling and thus regulates nitric oxide production in hypoxic pulmonary arterial endothelial cells from newborn piglets.
Prolonged hypoxia increased SNAT1 expression in pulmonary artery endothelial cells, enhancing the ability to transport l-citrulline.
Results found that SLC38A1 was up-regulated in colorectal cancer cells (CRC (show CALR Antibodies)) and significantly associated with tumor invasion and advanced disease stage. Its overexpression enhanced growth and migration of HCT116 cells providing evidence that activation of SLC38A1 may play a critical role in CRC (show CALR Antibodies) development and progression.
In the absence of SLC1A5 (show SLC1A5 Antibodies) there is a crucial role of SNAT1 in supplying glutamine (show GFPT1 Antibodies) for glutaminolysis with SNAT2 (show SLC38A2 Antibodies) acting as a "backup" for glutamine (show GFPT1 Antibodies) transport.
The SLC38A1 protein was very low or undetectable in healthy gastric mucosa but strong staining of SLC38A1 protein was found in the cytoplasm in more than half of gastric cancer samples. SLC38A1 knockdown decreased tumor cell proliferation and migration.
SLC38A1 and SLC38A2 (show SLC38A2 Antibodies) transcript levels are altered in placental malaria with intervillositis.
The cross-talk between Akt (show AKT1 Antibodies) signaling and SNAT1 might play a critical role in the development and progression of breast cancer
Increased expression of ATA1 is frequent in human hilar cholangiocarcinoma and significantly correlated with the progression of cholangiocarcinoma, suggesting the importance of ATA1 in cancer development and progression.
The results of this study provided that RAB2A (show RAB2A Antibodies) and SLC38A1, were associated with the density of calbindin (show CALB1 Antibodies)-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders.
results suggest that slc38a1 may play a role in the mechanisms underlying the determination of cellular viability in astrocytes through modulation of intracellular ROS (show ROS1 Antibodies) generation
SNAT1 is a key contributor to system A activity at term.
Theses data demonstrate the physiological importance of ATA1 in hepatocarcinogenesis.
Overexpression of X-box binding protein-1 (show XBP1 Antibodies) led to a marked increase in luciferase activity in P19 (show CDKN2D Antibodies) cells transfected with the Slc38a1 reporter plasmid. These results suggest that theanine accelerates cellular proliferation and subsequent neuronal specification through a mechanism relevant to upregulation of Slc38a1 gene in undifferentiated neural progenitor cells
We found that MeCP2 (show MECP2 PLURAL_@4252@) acts as a microglia-specific transcriptional repressor of
GlnT would promote both proliferation and neuronal differentiation through a mechanism relevant to the upregulation of particular proneural genes in undifferentiated P19 (show CDKN2D Antibodies) cells.
Inner hair cells express glutamine transporter SLC38A1.
In this study, the in vivo endothelial membrane localization of the sodium-dependent glutamine (show GFPT1 Antibodies) transporters Snat3 (Slc38a3 (show SLC38A3 Antibodies)) and Snat1 (Slc38a1) was investigated in the mouse brain microvasculature.
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001
sodium-coupled neutral amino acid transporter 1
, solute carrier family 38, member 1
, N-system amino acid transporter 2
, amino acid transporter A1
, amino acid transporter system A1
, system A amino acid transporter 1
, system N amino acid transporter 1
, glutamine transporter
, system A transporter 2