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anti-Spinster Homolog 2 (Drosophila) (SPNS2) Antibodies

Sphingolipid transporter required for migration of myocardial precursors. Additionally we are shipping SPNS2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPNS2 216892 Q91VM4
SPNS2 100270678  
SPNS2 124976 Q8IVW8
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Top anti-SPNS2 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Fruit Fly Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SPNS2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB SPNS2 Antibody (N-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SPNS2 antibody detected the SPNS2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 5 to 6 Days
$320.60
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

SPNS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)



Rat (Rattus) ,
,
,

Human , ,


, , , , ,

Top referenced anti-SPNS2 Antibodies

  1. Fruit Fly (Drosophila melanogaster) Polyclonal SPNS2 Primary Antibody for WB - ABIN493468 : Yanagisawa, Miyashita, Nakano, Yamamoto: HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. in Cell death and differentiation 2003 (PubMed)
    Show all 2 references for ABIN493468

More Antibodies against SPNS2 Interaction Partners

Zebrafish Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. Toh is required for signaling by S1P (show MBTPS1 Antibodies)(2)and is involved in the trafficking or cellular release of S1P (show MBTPS1 Antibodies).

  2. findings show that Spns2 in the yolk syncytial layer functions as a sphingosine-1-phosphate (S1P (show MBTPS1 Antibodies)) transporter in S1P (show MBTPS1 Antibodies) secretion, thereby regulating myocardial precursor migration

Mouse (Murine) Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. results point to a broad role for Spns2-mediated S1P (show S1PR1 Antibodies) transport in the initiation and development of adaptive immune related disorders

  2. Spns2 expression by endothelial cells is essential for secretion of lymph S1P (show S1PR1 Antibodies), while Spns2 is dispensable for RBC (show CACNA1C Antibodies) secretion of plasma S1P (show S1PR1 Antibodies).

  3. Spns2 is an S1P (show S1PR1 Antibodies) transporter in vivo that plays a role in regulation not only of blood S1P (show S1PR1 Antibodies) but also lymph node and lymph S1P (show S1PR1 Antibodies) levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization.

  4. SPNS2 is the first physiological S1P (show S1PR1 Antibodies) transporter in mammals and is a key determinant of lymphocyte egress from the thymus.

  5. The changes in lymphocyte subpopulations in mutant Spns2 mice closely mimick the phenotypes of partial sphingosine-1-phosphate (S1P (show S1PR1 Antibodies)) deficiency, impaired S1P (show S1PR1 Antibodies)-dependent lymphocyte trafficking, and depletion of circulating lymphocytes.

  6. Spns2 functions in endothelial cells to establish the S1P (show S1PR1 Antibodies) gradient required for T and B cells to egress from their respective primary lymphoid organs.

  7. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

Human Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. Spns2 plays key roles in regulating the cellular functions in non-small cell lung cancer (NSCLC) cells

  2. mammals. These findings indicate that Spns2 is required for normal maintenance of the endocochlear potential and hence for normal auditory function, and support a role for S1P (show MBTPS1 Antibodies) signalling in hearing.

  3. Spns2 is an S1P (show MBTPS1 Antibodies) transporter in vivo that plays a role in regulation not only of blood S1P (show MBTPS1 Antibodies) but also lymph node and lymph S1P (show MBTPS1 Antibodies) levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization.

  4. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

SPNS2 Antigen Profile

Protein Summary

Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration.

Gene names and symbols associated with SPNS2

  • spinster homolog 2 (Drosophila) (SPNS2) antibody
  • spinster homolog 2 (Drosophila) (spns2) antibody
  • spinster homolog 2 (spns2) antibody
  • spinster homolog 2 (Spns2) antibody
  • DKFZp459J1933 antibody
  • fi20h04 antibody
  • si:dkey-7b17.4 antibody
  • toh antibody
  • wu:fi20h04 antibody

Protein level used designations for SPNS2

spinster homolog 2 (Drosophila) , protein spinster homolog 2 , two of hearts , protein two of hearts , mCG6652-like , spinster-like protein , spinster2

GENE ID SPECIES
417492 Gallus gallus
568117 Danio rerio
606858 Canis lupus familiaris
613889 Bos taurus
100072726 Equus caballus
100145187 Xenopus (Silurana) tropicalis
100172034 Pongo abelii
216892 Mus musculus
100270678 Rattus norvegicus
124976 Homo sapiens
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