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May act as a protease inhibitor to modulate the host immune response against tumor cells.. Additionally we are shipping Squamous Cell Carcinoma Antigen 1 Kits (16) and Squamous Cell Carcinoma Antigen 1 Antibodies (3) and many more products for this protein.
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role of SERPINB3 (show SERPINB3 Proteins)/B4 mutations in immunotherapy response
Data show that in colorectal cancer SerpinB3 (show SERPINB3 Proteins), COX-2 and beta-Catenin (show CTNNB1 Proteins) are positively correlated and associated with more advanced tumor stage.
Results showed no correlation between gestational age and vaginal fluid SCC (show CYP11A1 Proteins) levels. There was no significant difference in vaginal fluid SCC (show CYP11A1 Proteins) levels between patients with premature rupture of membranes and those with control pregnant women.
Serum SCC (show CYP11A1 Proteins)-Ag level was an important predictor for the cervical squamous carcinoma recurrence and prognosis.
Data indicate that serum tumor markers showed significant shorter 3-year progression-free survival (PFS) in higher levels compared to lower levels for S-CYFRA 21-1 (cytokeratin 19 (show KRT19 Proteins) fragment), S-SCCA and S-CEA (show CEACAM5 Proteins).
SerpinB3 (show SERPINB3 Proteins) indirectly increased the transcription of Myc (show MYC Proteins) through the induction of Yap (show YAP1 Proteins) pathway.
Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1 (show SERPINB1 Proteins), SERPINB4 (show SERPINB4 Proteins) and SERPINB9 (show SERPINB9 Proteins) for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.
Data show that serum neuron-specific enolase (show ENO2 Proteins), cytokeratin 19 (show KRT19 Proteins) fragment 21-1, pro-gastrin-releasing peptide (show GRP Proteins), squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.
Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (show HLAE Proteins)-I and CD1d (show CD1D Proteins) expression. Intriguingly, expression of SERPINB9 (show SERPINB9 Proteins), SERPINB1 (show SERPINB1 Proteins), and SERPINB4 (show SERPINB4 Proteins) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors
The diagnostic performance of SCCA-IgM immune complexes for hepatocellular carcinoma was found to be frequently superior to that of alpha-fetoprotein (show AFP Proteins). (Review)
May act as a protease inhibitor to modulate the host immune response against tumor cells.
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3
, serpin B3
, squamous cell carcinoma antigen 1
, SCCA2/SCCA1 fusion protein
, peptidase inhibitor 11
, protease inhibitor (leucine-serpin)
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4
, serpin B4
, squamous cell carcinoma antigen 2