anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) Antibodies

SDHA encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Proteins (17) and Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SDHA 6389 P31040
SDHA 66945 Q8K2B3
SDHA 157074 Q920L2
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Top anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Anti- SDHA Picoband antibody, Western blotting All lanes: Anti SDHA  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Lane 3: Rat Brain Tissue Lysate at 50ug Lane 4: Mouse Brain Tissue Lysate at 50ug Lane 5: SMMC Whole Cell Lysate at 40ug Lane 6: Human Placenta Tissue Lysate at 50ug Lane 7: SW620 Whole Cell Lysate at 40ug Predicted bind size: 73KD Observed bind size: 73KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IF, SimWes, WB Western Blot: SDHA Antibody [NBP1-71688] - analysis of SDHA in whole skeletal muscle lysate or purified mitochondria from pig, mouse, lamb and goat using anti-SDHA antibody. Image from verified customer review. Immunocytochemistry/Immunofluorescence: SDHA Antibody [NBP1-71688] - SDHA antibody was tested at 1:100 in HeLa cells with FITC (green). Nuclei (Blue) were counterstained with Dapi (blue). 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image SDHA antibody [C1C3] detects SDHA protein at cytosol on mouse ovary by immunohistochemical analysis. Sample: Paraffin-embedded mouse ovary. SDHA antibody [C1C3] , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated WB SDHA Antibody (C-term) (ABIN1881780) western blot analysis in Hela and mouse C2C12 cell line lysates (35 µg/lane). This demonstrates the DHSA antibody detected the DHSA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Un-conjugated WB Anti-SDHA antibody, Western blotting Lane 1: Rat Heart Tissue Lysate Lane 2: COLO320 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of specific cells using SDHA Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse heart lysates probed with Rabbit Anti-SDHA Polyclonal Antibody, Unconjugated  at 1:500 for 90 min at 37˚C. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 7 to 9 Days
$669.17
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SDHA antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue Anti-SDHA antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

SDHA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Antibodies

  1. Human Polyclonal SDHA Primary Antibody for WB - ABIN1881780 : Hirawake, Wang, Kuramochi, Kojima, Kita: Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria. in Journal of biochemistry 1995 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal SDHA Primary Antibody for IF (p) - ABIN751910 : Krivitsky, Wang, Wang, Lukyanchuk: Locomotion of microspheres for super-resolution imaging. in Scientific reports 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SDHA Primary Antibody for ICC, IF - ABIN4352348 : Schild, Ruhs, Beiter, Zügel, Hudemann, Reimer, Krumholz-Wagner, Wagner, Keller, Eder, Krüger, Krüger, Braun, Nieß, Steinacker, Mooren: Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals. in Journal of proteomics 2015 (PubMed)

More Antibodies against Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Interaction Partners

Human Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) interaction partners

  1. This is only the second report supporting the dominant nature of the SDHA c.1351C>T (p.Arg451Cys) mutation being causative for an autosomal dominantly inherited mitochondrial metabolic disorder expanding the phenotypic presentation to an earlier onset of disease with additional cardiac involvement.

  2. The SDHA, TMEM127 (show TMEM127 Antibodies), MAX, and SDHAF2 (show Sdhaf2 Antibodies) genes contribute to hereditary pheochromocytoma and paraganglioma.

  3. SDH (show SARDH Antibodies)-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

  4. For classification, tumors were characterized by SDHA, B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline

  5. data show that SDHA flavination is independent of SDHAF2 (show Sdhaf2 Antibodies) in breast cancer cells, employing an alternative mechanism.

  6. FAD (show BRCA2 Antibodies) interacts noncovalently with SDHA in the absence of SDH5 (show Sdhaf2 Antibodies)

  7. After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase, FH and MCT (show MCAT Antibodies) expression were increased. After the MCT1 (show CMA1 Antibodies)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.

  8. Data suggest that succinate dehydrogenases SDHA and SDHB (show SDHB Antibodies) immunohistochemistry should be interpreted with caution, due to possible false-positive or false-negative results, and ideally in the setting of quality assurance provided by molecular testing.

  9. Combined blockade of CDK (show CDK4 Antibodies) and SDH (show SARDH Antibodies), both genetically and pharmaceutically, showed synergy and resulted in inhibited proliferation, migration, invasion and migration in A2780 cells Cyclin E (show CCNE1 Antibodies)-driven OvCa cells appeared addicted to glucose metabolism via TCA. Combined CDKi (show CDKN1C Antibodies) with modalities targeting TCA, like SDHA inhibition showed promising effects for this genotype.

  10. According to international guidelines, SDHB (show SDHB Antibodies), SDHC (show SDHC Antibodies), and SDHD (show SDHD Antibodies) genetic testing were performed in this patient, but not SDHA, which would have been prescribed only after surgery, in case of SDHA negative immunohistochemistry

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) interaction partners

  1. Tumor-derived FH and SDH (show SDS Antibodies) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS Antibodies).

  2. Data show that SdhA is required for preventing AIM2 (show AIM2 Antibodies) inflammasome activation.

  3. Data show that two subunits of complex II (succinate dehydrogenase (show SDHD Antibodies), or SDH (show SDS Antibodies)), SDHA and SDHB (show SDHB Antibodies), interacted specifically with SIRT3 (show SIRT3 Antibodies).

  4. Cocaine could inhibit the activities of ATPase (show DNAH8 Antibodies), LDH and SDH (show SDS Antibodies) in cultured splenocytes.

Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) Antigen Profile

Protein Summary

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.

Gene names and symbols associated with SDHA

  • Succinate dehydrogenase A (SdhA) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (Sdha) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (sdha) antibody
  • 1500032O14Rik antibody
  • 2310034D06Rik antibody
  • 4921513A11 antibody
  • C81073 antibody
  • CG17246 antibody
  • CMD1GG antibody
  • Dmel\\CG17246 antibody
  • Fp antibody
  • im:7141001 antibody
  • PGL5 antibody
  • scs-fp antibody
  • sdh antibody
  • SDH1 antibody
  • SDH2 antibody
  • Sdha antibody
  • sdha-b antibody
  • SDHF antibody
  • zgc:56051 antibody

Protein level used designations for SDHA

CG17246-PA , CG17246-PB , CG17246-PC , COMPLEX II: flavoprotein subunit , SUCCINYL COENZIME A SYNTHETASE FLAVOPROTEIN SUBUNIT , SdhA-PA , SdhA-PB , SdhA-PC , succinate dehydrogenase , succinate dehydrogenase A , succinate dehydrogenase flavoprotein , succinate dehydrogenase flavoprotein subunit , succinyl coenzyme A synthetase flavoprotein subunit , flavoprotein subunit of complex II , succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial , succinate dehydrogenase complex flavoprotein subunit , fp , succinate dehydrogenase complex subunit A , succinate dehydrogenase flavoprotein subunit A , succinate dehydrogenase Fp subunit , Flavoprotein subunit of complex II , Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial , mitochondrial succinate dehydrogenase complex subunit A , succinate dehydrogenase complex subunit A flavoprotein , flavoprotein subunit of complex II B , succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial

GENE ID SPECIES
37228 Drosophila melanogaster
6389 Homo sapiens
66945 Mus musculus
157074 Rattus norvegicus
393884 Danio rerio
281480 Bos taurus
395758 Gallus gallus
780433 Sus scrofa
380463 Xenopus laevis
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