Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Proteins (SDHB)

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Antibodies (127) and Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SDHB 6390 P21912
SDHB 67680 Q9CQA3
SDHB 298596 P21913
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Top Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 60 to 71 Days
$2,643.67
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,647.33
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,647.33
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Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,647.33
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Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$2,656.50
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Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,660.17
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SDHB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Interaction Partners

Fruit Fly (Drosophila melanogaster) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. sdhB mutant is hypersensitive to oxygen and displays hallmarks of a progeroid syndrome

Human Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. we found a higher estimated penetrance compared to several other studies, and a striking difference in age-related penetrance between male and female SDHB mutation carriers with no association between mutation and gender or tumor location

  2. LASS5 (show LASS5 Proteins) interacts with SDHB and synergistically represses p53 (show TP53 Proteins) and p21 (show CDKN1A Proteins) activity.

  3. A novel SDHB germline mutation in a paraganglioma

  4. SDHB-related tumours are picked up as early as 2 years after initial negative surveillance scan

  5. miR (show MLXIP Proteins)-183 cluster (miR (show MLXIP Proteins)-96/182/183) are related to clinical parameters and SDHB expression in pheochromocytomas.

  6. In SDHB mutation carriers, a lower rate of metastatic disease and a higher number of head and neck paragangliomas compared to previous reports was observed in a nationwide study in the Netherlands.

  7. Loss of FH immunohistochemical (IHC) expression in cutaneous leiomyomas is a sensitive and specific marker for detection of hereditary leiomyomatosis and renal cell carcinoma (show MOK Proteins) (HLRCC (show FH Proteins)). FH expression by IHC was absent in 9 specimens and retained in 85 specimens and 2 cases were equivocal with minimal FH expression while succinate dehydrogenase B expression was retained in 95 specimens and equivocal in 1 specimen.

  8. Identify small molecule binding to the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain to block mitochondrial apoptotic pathway.

  9. We have shown that ASO treatment diminished aberrant splicing and increased ISCU (show ISCU Proteins) protein levels in both patient fibroblasts and patient myotubes in a concentration dependent fashion. Upon ASO treatment, levels of SDHB in patient myotubular cell lines increased to levels observed in control myotubular cell lines

  10. SDH-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

Pig (Porcine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. tissue expression analysis indicated that that swine SDHB, SNRPA (show SNRPA Proteins) and CRYBB1 (show CRYBB1 Proteins) gene were differentially expressed in tissues including fat, lung, muscle, small intestine, kidney, large intestine, spleen and liver

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. Data show that lack of succinate dehydrogenase (SDH (show SDHA Proteins)) activity commits cells to consume extracellular pyruvate.

  2. Using Sdhb(+/-) mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to pituitary adenoma formation.

  3. Tumor-derived FH and SDH (show SDS Proteins) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS Proteins).

  4. Data show that two subunits of complex II (succinate dehydrogenase (show SDHD Proteins), or SDH (show SDS Proteins)), SDHA (show SDHA Proteins) and SDHB, interacted specifically with SIRT3 (show SIRT3 Proteins).

Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Protein Profile

Protein Summary

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Gene names and symbols associated with SDHB

  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB)
  • succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 (SDH2-3)
  • Succinate dehydrogenase B (SdhB)
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (sdhb)
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (Sdhb)
  • 0710008N11Rik protein
  • CG3283 protein
  • CWS2 protein
  • Dmel\\CG3283 protein
  • fj46d06 protein
  • IP protein
  • PGL4 protein
  • SDH protein
  • SDH-Ip protein
  • SDH1 protein
  • SDH2 protein
  • sdhB protein
  • SDHIP protein
  • succinate dehydrogenase 2-3 protein
  • wu:fj46d06 protein

Protein level used designations for SDHB

succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial , succinate dehydrogenase complex subunit B , CG3283-PA , COMPLEX II: iron-sulfur subunit , SdhB-PA , iron-sulfur protein subunit of succinate dehydrogenase , succinate dehydrogenase , succinate dehydrogenase B , succinate dehydrogenase Iron-sulfur , succinate dehydrogenase Iron-sulfur protein , succinate dehydrogenase iron protein , succinate dehydrogenase subunit b , iron-sulfur subunit of complex II , Iron-sulfur subunit of complex II , IP , ip

GENE ID SPECIES
100050091 Equus caballus
770063 Arabidopsis thaliana
35590 Drosophila melanogaster
100144957 Xenopus (Silurana) tropicalis
6390 Homo sapiens
478217 Canis lupus familiaris
414412 Sus scrofa
286840 Bos taurus
100328585 Oryctolagus cuniculus
67680 Mus musculus
298596 Rattus norvegicus
562149 Danio rerio
379939 Xenopus laevis
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