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SUCLG2 encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Additionally we are shipping Succinate-CoA Ligase, GDP-Forming, beta Subunit Antibodies (19) and many more products for this protein.
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The absence of SUCLA2 (show SUCLA2 Proteins) and SUCLG2 in human glia is in compliance with the presence of alternative pathways occurring in these cells, namely the GABA shunt and ketone body metabolism
SUCLG2 has been identified as both a determinator of CSF (show CSF2 Proteins) amyloid beta-protein (1 (show DLX4 Proteins)-42) levels and as attenuator of cognitive decline in Alzheimer's disease.
Loss of SUCLG2 is associated with mitochondrial DNA depletion and results in mitochondrial depletion syndrome.
This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12.
GTP-specific succinyl-CoA synthetase beta subunit
, GTP-specific succinyl-CoA synthetase subunit beta
, succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial
, succinyl-CoA synthetase beta-G chain
, succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial
, succinyl-CoA synthetase, beta-G chain
, succinate-CoA ligase, GDP-forming beta subunit
, Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial
, succinyl-CoA synthetase beta-subunit