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Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Additionally we are shipping TIAF1 Antibodies (12) and and many more products for this protein.
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Human TIAF1 Protein expressed in Escherichia coli (E. coli) - ABIN1098676
Chang, Mattison, Cao, Pratt, Zhao, Lee: Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity. in Biochemical and biophysical research communications 1999
Show all 2 references for ABIN1098676
MYO18A likely functions in the adhesion process that maintains the stable attachment of myofibers to ECM (show MMRN1 Proteins) (extracellular matrix) and muscle integrity during early development
In vitro induction of TIAF1 self-association upregulated the expression of tumor suppressors Smad4 (show SMAD4 Proteins) and WW domain-containing oxidoreductase (WOX1 (show WWOX Proteins) or WWOX (show WWOX Proteins)), and WOX1 (show WWOX Proteins) in turn increased the TIAF1 expression.
TIAF1 undergoes self-aggregation in response to TGF-Beta1 (show TGFB1 Proteins).
Expression of TIAF-1 in the lymphocytes during chronic allograft rejection may be related to the predominance of a Th2 response in this condition and may protect these cells from apoptosis
TIAF1 and p53 (show TP53 Proteins) functionally interact in regulating apoptosis, and TIAF1 is likely to participate in the nuclear translocation of activated p53 (show TP53 Proteins).
Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
myosin XVIII-like 1
, TGFB1-induced anti-apoptotic factor 1
, TGFB-1-induced anti-apoptotic factor 1
, 12 kDa TGF-beta-1-induced antiapoptotic factor
, TGF-beta-1-induced antiapoptotic factor 1
, molecule associated with Jak-3 N-terminal