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TIMELESS Interacting Protein (TIPIN) ELISA Kits

Required for normal progression of S-phase. Additionally we are shipping TIPIN Antibodies (68) and TIPIN Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TIPIN 100359731  
TIPIN 54962 Q9BVW5
TIPIN 66131 Q91WA1
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Top TIPIN ELISA Kits at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Human
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$875.60
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Rat
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$875.60
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Cow
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$1,029.60
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Chicken
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$1,095.60
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Dog
96 Tests Log in to see 16 to 21 Days
$999.43
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Guinea Pig
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$999.43
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Monkey
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$999.43
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Rabbit
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$999.43
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More ELISA Kits for TIPIN Interaction Partners

Xenopus laevis TIMELESS Interacting Protein (TIPIN) interaction partners

  1. Mta2 (show MTA2 ELISA Kits) and Tipin cooperate to maintain replication fork integrity, especially on regions that are intrinsically difficult to duplicate.

  2. data indicate that Tipin/Tim1/And1 (show WDHD1 ELISA Kits) form a complex that links stabilization of replication fork and establishment of sister chromatid cohesion

Human TIMELESS Interacting Protein (TIPIN) interaction partners

  1. TIPIN is important for the maintenance of DNA replication and represents a potential treatment target for the worst prognosis associated breast cancers, such as Triple-negative breast cancer.

  2. Tim-Tipin complex (or Tim alone) is able to associate with DNA polymerase epsilon bound to a 40-/80-mer (show MERTK ELISA Kits) DNA ligand.

  3. Tim-Tipin complex might play a role in coupling DNA unwinding and DNA synthesis by directly affecting the catalytic activities of replication fork proteins.

  4. We now show that cellular DNA replication fork pausing and protection factors Timeless (Tim) and Tipin (Timeless-interacting protein) accumulate at OriP during S phase of the cell cycle.

  5. RPA (show RPA1 ELISA Kits)-covered ssDNA not only supports recruitment and activation of ATR (show ANTXR1 ELISA Kits) but also, through Tipin and Claspin (show CLSPN ELISA Kits), it plays an important role in the action of ATR (show ANTXR1 ELISA Kits) on its critical downstream target Chk1 (show CHEK1 ELISA Kits)

  6. The results suggest that Timeless-Tipin functions as a replication fork stabilizer that couples DNA replication with sister chromatid cohesion established at replication forks.

  7. Tipin is a checkpoint mediator that cooperates with Tim and may regulate the nuclear relocation of Claspin (show CLSPN ELISA Kits) in response to replication checkpoint

  8. observation explains the similar checkpoint phenotypes observed in both Tipin- and Timeless-depleted cells

  9. TIM and Tipin are functional orthologs of their replisome-associated yeast counterparts capable of coordinating replication with genotoxic stress responses, and distinguishes mammalian TIM from the circadian-specific paralogs.

  10. These findings indicate that the Tim-Tipin complex mediates the UV-induced intra-S checkpoint, Tim is needed to maintain DNA replication fork movement, Tipin interacts with RPA on DNA.

Mouse (Murine) TIMELESS Interacting Protein (TIPIN) interaction partners

  1. mTIM promotes the nuclear localization of TIPIN, and TIPIN is capable of regulating mTIM activity by disrupting the ability of mTIM to form homo-multimeric complexes

  2. TIM and Tipin are functional orthologs of their replisome-associated yeast counterparts capable of coordinating replication with genotoxic stress responses, and distinguishes mammalian TIM from the circadian-specific paralogs.

  3. The tim-Tipin dysfunction creates an indispensible reliance on the ATR (show ATR ELISA Kits)-Chk1 (show CHEK1 ELISA Kits) pathway for continued DNA synthesis.

TIPIN Antigen Profile

Antigen Summary

Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be required in the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity).

Gene names and symbols associated with TIPIN

  • timeless interacting protein (tipin) antibody
  • TIMELESS interacting protein (TIPIN) antibody
  • timeless interacting protein (LOC100359731) antibody
  • timeless interacting protein (Tipin) antibody
  • XTimeless interacting protein (xtipin) antibody
  • 1110005A05Rik antibody
  • 1110018P21Rik antibody
  • MGC82649 antibody
  • RGD1564084 antibody
  • tipin antibody
  • zgc:91928 antibody

Protein level used designations for TIPIN

timeless interacting protein , TIMELESS interacting protein , timeless-interacting protein , TIMELESS-interacting protein , CSM3 homolog , mitotic phosphoprotein 67

GENE ID SPECIES
444047 Xenopus laevis
453525 Pan troglodytes
100126681 Xenopus (Silurana) tropicalis
100359731 Rattus norvegicus
445058 Danio rerio
415548 Gallus gallus
54962 Homo sapiens
100683743 Canis lupus familiaris
506176 Bos taurus
66131 Mus musculus
363076 Rattus norvegicus
394376 Xenopus laevis
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