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TACR1 belongs to a gene family of tachykinin receptors. Additionally we are shipping TACR1 Kits (34) and TACR1 Proteins (9) and many more products for this protein.
Showing 10 out of 149 products:
Human Polyclonal TACR1 Primary Antibody for ICC, FACS - ABIN152468
Lai, Ho, Kilpatrick, Wang, Tuluc, Korchak, Douglas: Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 34 references for ABIN152468
Guinea Pig Polyclonal TACR1 Primary Antibody for ICC, IHC (fro) - ABIN152451
Anderson, Seybold: Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception. in Neuroscience letters 2000
Show all 30 references for ABIN152451
Human Monoclonal TACR1 Primary Antibody for ELISA - ABIN395116
Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: Association study of 182 candidate genes in anorexia nervosa. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010
Show all 5 references for ABIN395116
Dog (Canine) Polyclonal TACR1 Primary Antibody for WB - ABIN374799
Garcia, Coello, Han, Radko, Bozhevolnyi: Partial loss compensation in dielectric-loaded plasmonic waveguides at near infra-red wavelengths. in Optics express 2012
Show all 2 references for ABIN374799
Human Polyclonal TACR1 Primary Antibody for ICC, IF - ABIN261566
Cavanaugh, Lee, Lo, Shields, Zylka, Basbaum, Anderson: Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. in Proceedings of the National Academy of Sciences of the United States of America 2009
Human Polyclonal TACR1 Primary Antibody for ELISA, WB - ABIN1535783
Gerard, Garraway, Eddy, Shows, Iijima, Paquet, Gerard: Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. in Biochemistry 1991
Human Polyclonal TACR1 Primary Antibody for WB - ABIN657820
Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. in Journal of psychiatric research 2010
We showed that pretreating a cardiomyocyte cell line (H9C2) and a TNBC cell line (MDA-MB 231) with aprepitant, a SP receptor antagonist that is routinely used to treat chemotherapy-associated nausea, decreased DOX-induced reduction of viability, apoptotic cell death, and ROS (show ROS1 Antibodies) production in cardiomyocytes
These findings reveal important insight into the molecular mechanisms of the NK1R complex as a critical component in a model of pediatric liver cancer and may support the development of novel therapeutic interventions for hepatoblastoma
Neuropeptide signaling through neurokinin-1 (show TAC1 Antibodies) and neurokinin-2 (show TAC1 Antibodies) receptors augments antigen presentation by human dendritic cells
Inhibition of CaV2.3 (show CACNA1E Antibodies) channels by NK1 (show CD160 Antibodies) receptors is sensitive to membrane cholesterol but insensitive to caveolin-1 (show CAV1 Antibodies).
NK-1 (show CD160 Antibodies) activation could enhance EGFR (show EGFR Antibodies) expression and phosphorylation, and then activate EGFR (show EGFR Antibodies) related Erk/MAPK (show MAPK1 Antibodies) and Akt (show AKT1 Antibodies) pathway.
The single nucleotide polymorphisms in the TACR1 gene are associated with sex differences in postoperative nausea and vomiting.
Results show the existence of a relevant alteration in NK-1R expression in bipolar disorder patients and further suggest Substance P (show TAC1 Antibodies) involvement in BD.
Immunohistochemical NK-1R and pEGFR positivity with VDR (show CYP27B1 Antibodies) negativity can be used to identify areas of sporadic colorectal neoplasia.
Hepatoblastoma cells predominantly expressed the truncated splice variant of NK1R.
Findings indicate a role of the TACR1 gene in the development of sicca syndrome in subjects affected with fibromyalgia.
NK1R-/- mice did not exhibit excessive false alarms, compared with wildtypes (response disinhibition) but, as in the 5-Choice ContinuousPerformance Test, they exhibited more perseverative responses throughout the test
NK1R-expressing dorsal horn neurons play a major role in the expression of symptoms of chronic itch.
The results of this study indicated that certain behaviours, disrupted in ADHD, are influenced by an interaction between the BRAS and NK1R, and suggest that ACE (show ACE Antibodies) inhibitors could provide a novel treatment for this disorder.
Results provide evidence linking enhanced waking activity and the pro-inflammatory molecule substance P (show TAC1 Antibodies) to changes in slow-wave activity associated with sleep-active cortical cells that co-express nNOS (show NOS1 Antibodies) and the NK-1R
the hyperactivity, perseveration and, possibly, inattentiveness of NK1R-/- mice is a direct consequence of a lack of functional NK1R
Substance P (show TAC1 Antibodies) partly accounts for the increased density of microglia in the substantia nigra through chemotaxic recruitment via a novel NK1R-NOX2 (show CYBB Antibodies) axis-mediated pathway.
NK1 (show HGF Antibodies)-R expression in the trachea, bronchus, and lung tissue increased in MP-infected BALB/c mice, which may explain why wheezing occurs after MP infection.
The behavioural response of mice lacking NK1r to guanfacine resembles its clinical profile in treatment of ADHD
Together, our findings revealed a critical role of microglial NOX2 (show CYBB Antibodies) in mediating the neuroinflammatory and dopaminergic neurodegenerative effects of SP, which may provide new insights into the pathogenesis of PD.
Both PACAP (show ADCYAP1 Antibodies) and SP/NKA, but not NK1 (show HGF Antibodies) receptors participate in normal motor coordination.
Implanting vascular bundles into the tissue engineered bone can significantly improve the expression levels of NK1R and VIPR1 (show VIPR1 Antibodies).
Activation of neurokinin-1 (show TAC1 Antibodies) receptors in primary sensory neurons plays a role in the generation of overactive bladder.
Substance P (show TAC1 Antibodies) and SP-R mRNA expressions were reduced after IMETIT treatment of allergic rhinitis.
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.
, substance-P receptor
, tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
, Nk1 receptor
, neurokinin receptor 1
, substance P receptor
, neurokinin 1 receptor
, substance p receptor
, neurokinin receptor subtype NK1
, tachikinin receptor 1
, tachykinin receptor 1
, neurokinin-1 receptor