anti-Tafazzin (TAZ) Antibodies

TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Additionally we are shipping TAZ Proteins (13) and TAZ Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAZ 6901 Q16635
TAZ 66826  
TAZ 363521  
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Top anti-TAZ Antibodies at antibodies-online.com

Showing 10 out of 144 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Lanes: Lane 1:241 µg mouse cardiac mitochondria lysate Lane 2: 041 µg mouse cardiac mitochondria lysate <br /> Lane 3: 041 µg mouse cardiac mitochondria lysate <br />  ane 4: 041 µg mouse cardiac mitochondria lysate <br />Primary Antibody Dilution: 1:000<br />Secondary Antibody: Goat anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:0500 <br /> Gene Name: TAZ An <br /><br />Submitted by: Corey Powers, Cincinati Children's Hospital Medical Center 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated BI, WB Western blot analysis of TAZ in transformed human epithelioid carcinoma. HeLa cell lysate (ABIN968535) was probed with Purified Mouse anti-TAZ monoclonal antibody at concentrations of 0.5, 0.25, and 0.125 µg/ml (lanes 1, 2, and 3, respectively). TAZ is identified as a band of 49 kDa. Immunofluorescent staining of human cell lines. HeLa cells (ATCC CCL-2) were seeded in two 96-well imaging plates at ~10,000 cells per well. After overnight incubation, the cells were fixed, permeabilized with Saponin, and stained with Purified Mouse anti-TAZ (pseudocolored green) according to the Recommended Assay Procedure. The second-step reagent was Alexa Fluor® 555 goat anti-mouse Ig (Invitrogen). The left image shows TAZ alone, and the right image shows TAZ merged with Hoechst staining. Images were captured on a BD Pathway™ 435 bioimager using a 20x objective and merged using BD AttoVision™ software. Other permeabilization methods, cold methanol and Triton™ X-100, did not work well. 0.1 mg Log in to see 6 to 8 Days
$247.40
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded rat heart, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with TAZ Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. Lane 1: mouse lung lysates probed with 	TAZ Polyclonal Antibody, Unconjugated  at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:10000 for 90 min at 37˚C. 100 μL Log in to see 14 to 21 Days
$307.45
Details
Human Goat Un-conjugated ELISA, WB ABIN185489 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TAZ Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). TAZ (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TAZ Antibody (N-term) (ABIN652751) in MDA-MB231, NCI-H460 cell line lysates (35 µg/lane). TAZ (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged TAZ is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged TAZ is approximately 10 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB Anti-Tafazzin/TAZ antibody, Western blotting Lane 1: Rat Skeletal Muscle Tissue Lysate Lane 2: Rat Heart Tissue Lysate Lane 3: Rat Liver Tissue Lysate Lane 4: HELA Cell Lysate Lane 5: SMMC Cell Lysate Lane 6: SCG Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$306.90
Details

TAZ Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TAZ Antibodies

  1. Human Monoclonal TAZ Primary Antibody for ELISA, WB - ABIN520708 : Raghunathan, Morgan, Dreier, Reilly, Thomasy, Wood, Ly, Tuyen, Hughbanks, Murphy, Russell: Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ. in Investigative ophthalmology & visual science 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal TAZ Primary Antibody for BI, WB - ABIN967665 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal TAZ Primary Antibody for IF (p), IHC (p) - ABIN1713913 : Sun, Chen, Shi, Qi, Zhao, Zhang: Prognostic impact of TAZ and ?-catenin expression in adenocarcinoma of the esophagogastric junction. in Diagnostic pathology 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal TAZ Primary Antibody for ELISA, WB - ABIN269827 : Brandner, Mick, Frazier, Taylor, Meisinger, Rehling: Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. in Molecular biology of the cell 2005 (PubMed)

More Antibodies against TAZ Interaction Partners

Zebrafish Tafazzin (TAZ) interaction partners

  1. During vascular regression, Yap/Taz is activated by blood circulation in the endothelial cells. This leads to induction of Ctgf and actin polymerization. Interference with Yap/Taz activation decreased Ctgf production, which decreased actin polymerization and vascular regression.

  2. knockdown phenotype demonstrates that abnormal cardiac development, with a linear, nonlooped heart, and hypomorphic tail and eye development proves that tafazzin is essential for overall zebrafish development, especially of the heart.

Human Tafazzin (TAZ) interaction partners

  1. TAZ was positively correlated with EGFR (show EGFR Antibodies) signaling, and coexpression of TAZ/EGFR (show EGFR Antibodies) conferred a poorer prognosis in lung cancer patients. Our findings identify that targeting TAZ-mediated compensatory mechanism is a novel therapeutic approach to overcome gefitinib resistance in KRAS-mutant/EGFR (show EGFR Antibodies)-wild-type non-small-cell lung cancer .

  2. TAZ mutation-confirmed diagnosis of Barth syndrome (BTHS) was available for 39/42 of the participants. Of 39 patients, 13 have a missense mutation, 6 have a nonsense mutation, 8 have a splicing mutation, 6 have a small out-of-frame insertion or deletion, 2 have a small in-frame insertion, and 4 have a large deletion encompassing several exons

  3. establish a new cancer stem cell signalling pathway downstream of mtp53 in which AKT2 (show AKT2 Antibodies) regulates WIP (show WIPF1 Antibodies) and controls YAP (show YAP1 Antibodies)/TAZ stability.

  4. High TAZ expression is associated with non-small cell lung cancer.

  5. TAZ is overexpressed in cervical cancer and may promote tumorigenicity of cervical cancer cells and inhibit apoptosis.

  6. TAZ mutation is associated with Barth syndrome.

  7. Wnt (show WNT2 Antibodies) signaling upregulated WBP2 (show WBP2 Antibodies) by disrupting ITCH-WBP2 (show WBP2 Antibodies) interactions via EGFR (show EGFR Antibodies)-mediated tyrosine phosphorylation of WBP2 (show WBP2 Antibodies) and TAZ/YAP (show YAP1 Antibodies) competitive binding.

  8. Data suggest that 14-3-3 sigma protein (show SFN Antibodies) exhibits two individual secondary binding sites for peptide fragments of TAZ protein; these two pockets appear to be part of at least three physiologically relevant and structurally characterized 14-3-3 protein (show YWHAE Antibodies)-protein interaction interfaces.

  9. AXL (show AXL Antibodies)/TAZ/YAP (show YAP1 Antibodies) expression is associated with poor prognosis in male breast cancer patients.

  10. results highlight both CYR61 (show CYR61 Antibodies) and TAZ genes as potential predictive biomarkers for stratification of the risk for development of adenocarcinoma and suggest a potential mechanistic route for Barrett's esophagus neoplastic progression

Mouse (Murine) Tafazzin (TAZ) interaction partners

  1. The results uncover an important aspect of the cross-talk between TGFbeta (show TGFB1 Antibodies) and Hippo signaling, showing that TGFbeta (show TGFB1 Antibodies) induces TAZ via a Smad3 (show SMAD3 Antibodies)-independent, p38 (show CRK Antibodies)- and MRTF-mediated and yet MRTF translocation-independent mechanism.

  2. Wnt/beta-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers

  3. Epicardial YAP (show YAP1 Antibodies)/TAZ orchestrate an immunosuppressive response following myocardial infarction

  4. Yap (show YAP1 Antibodies) and Taz are activated in Schwann cells by mechanical stimuli and regulate Schwann cell proliferation and transcription of basal lamina receptor genes

  5. transient expression of exogenous YAP (show YAP1 Antibodies) or its closely related paralogue TAZ in primary differentiated mouse cells can induce conversion to a tissue-specific stem/progenitor cell state.

  6. The impact of endurance training on the cardiac and skeletal muscle phenotype in young TAZ knock-down mice.

  7. impaired Taz-function with onset at adult age does not enhance susceptibility to ischemia-reperfusion injury.

  8. A novel role for Taz in helping to maintain genome integrity in spermatocyte meiosis and facilitating germ cell differentiation.

  9. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  10. TAZ mutation is necessary and sufficient for the phenotype of sparse and irregular sarcomeres and weak myocaridal contraction foudn in Barth syndrome.

TAZ Antigen Profile

Protein Summary

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced\; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Gene names and symbols associated with anti-Tafazzin (TAZ) Antibodies

  • tafazzin (TAZ) antibody
  • tafazzin (taz) antibody
  • tafazzin (Taz) antibody
  • tafazzin (AFUA_2G13960) antibody
  • tafazzin (AOR_1_318014) antibody
  • tafazzin (Tsp_06712) antibody
  • Tafazzin (taz) antibody
  • 5031411C02Rik antibody
  • 9130012G04Rik antibody
  • Afu2g13960 antibody
  • AW107266 antibody
  • AW552613 antibody
  • BTHS antibody
  • CMD3A antibody
  • EFE antibody
  • EFE2 antibody
  • G4.5 antibody
  • GB11956 antibody
  • LVNCX antibody
  • MGC54019 antibody
  • taz antibody
  • Taz1 antibody
  • wu:fb39f12 antibody
  • zgc:91803 antibody

Protein level used designations for anti-Tafazzin (TAZ) Antibodies

tafazzin , Tafazzin , protein G4.5 , Barth syndrome) , endocardial fibroelastosis 2 , tafazzin (cardiomyopathy, dilated 3A (X-linked) , tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)

GENE ID SPECIES
100446947 Pongo abelii
321965 Danio rerio
379259 Xenopus laevis
515177 Bos taurus
549220 Xenopus (Silurana) tropicalis
550948 Apis mellifera
3513201 Aspergillus fumigatus Af293
5993687 Aspergillus oryzae RIB40
10911739 Trichinella spiralis
100137265 Papio anubis
100196028 Salmo salar
100328759 Oryctolagus cuniculus
100528715 Ictalurus punctatus
6901 Homo sapiens
66826 Mus musculus
363521 Rattus norvegicus
612975 Canis lupus familiaris
449590 Pan troglodytes
574297 Macaca mulatta
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