anti-Testis Derived Transcript (3 LIM Domains) (TES) Antibodies

Cancer-associated chromosomal changes often involve regions containing fragile sites. Additionally we are shipping Testis Derived Transcript (3 LIM Domains) Proteins (26) and Testis Derived Transcript (3 LIM Domains) Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TES 286916 P15242
TES 21753  
TES 26136 Q9UGI8
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Top anti-Testis Derived Transcript (3 LIM Domains) Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to TES on HeLa cell (antibody concentration 10 µg/mL).  Western Blot analysis of TES expression in transfected 293T cell line by TES monoclonal antibody (M01), clone 1G11-B7. Lane 1: TES transfected lysate(48 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB TES Antibody (N-term) (ABIN1881876) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the TES antibody detected the TES protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: Testin Antibody  - Analysis in human cell line EFO-21. Immunocytochemistry/Immunofluorescence: Testin Antibody  - Staining of human cell line SiHa shows positivity in cytoplasm and focal adhesion sites. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Mouse Biotin ICC, IHC, ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details
Human Mouse APC ICC, IHC, ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details
Human Mouse PE ICC, IHC, ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IHC, ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details

TES Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Mouse (Murine)


Human
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Top referenced anti-Testis Derived Transcript (3 LIM Domains) Antibodies

  1. Human Polyclonal TES Primary Antibody for WB - ABIN1881876 : Qiu, Zhu, Yuan, Yan, Yang, Kong: Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer. in Cancer science 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TES Primary Antibody for ICC, IF - ABIN4358534 : Danielsson, Wiking, Mahdessian, Skogs, Ait Blal, Hjelmare, Stadler, Uhlén, Lundberg: RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins. in Journal of proteome research 2013 (PubMed)

More Antibodies against Testis Derived Transcript (3 LIM Domains) Interaction Partners

Mouse (Murine) Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. zyxin (show ZYX Antibodies) influences focal adhesion dynamics, that it recruits Tes and that this interaction is functional in regulating cell spreading.

  2. Testin is a mammalian gene involved in coordinated orientation of hair cells in the inner ear and in the development of the female reproductive tract.

  3. TES acts as a tumor suppressor in an established model of carcinogen-induced gastric cancer

Human Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. testin region (amino acids 52-233) harbouring the PET domain interacts with the C-terminal LIM1 (show LHX1 Antibodies)-2 domains

  2. Testin plays an important role in the development and progression of non-small cell lung cancer. Testin is a tumor suppressor.

  3. VASP (show VASP Antibodies), zyxin (show ZYX Antibodies) and TES are tension-dependent members of focal adherens junctions independent of the alpha-catenin (show CTNNA1 Antibodies)-vinculin (show VCL Antibodies) module.

  4. we confirm that the TES promoter is unmethylated in normal adult and fetal tissues. Re-expression of TESTIN protein in acute lymphoblastic leukemia cells using expression plasmid transfection results in rapid cell death or cell cycle arrest.

  5. Loss of TES gene expression is associated with nasopharyngeal carcinoma.

  6. findings suggest that the TES gene is a novel tumor suppressor gene

  7. TESTIN was hypermethylated in 43.7% endometrial cancer tissues (p < 0.001). Moreover, TESTIN hypermethylation was significantly correlated with advanced tumor stage, deep myometrial invasion and lymphatic node metastasis.

  8. Downregulation of TES was associated with breast cancer.

  9. TESTIN was commonly downregulated in human endometrial carcinoma and was associated with poor prognostic markers.

  10. A further significant correlation was observed between TES downregulation and the luminal B subtype independent of survivin (show BIRC5 Antibodies) expression.

Xenopus laevis Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. Prickle and tes act together to control axial elongation.

Testis Derived Transcript (3 LIM Domains) (TES) Antigen Profile

Protein Summary

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Gene names and symbols associated with TES

  • testis derived transcript (3 LIM domains) (tes) antibody
  • testis derived transcript (3 LIM domains) (TES) antibody
  • testin gene (Testin) antibody
  • testin-like (LOC100407335) antibody
  • testis derived transcript (Tes) antibody
  • D6Ertd352e antibody
  • DKFZp469E2320 antibody
  • TES antibody
  • Tes1 antibody
  • Tes2 antibody
  • TESS antibody
  • TESS-2 antibody
  • Testin antibody
  • testin2 antibody
  • xtes antibody
  • zgc:92091 antibody

Protein level used designations for TES

testin , testis derived transcript (3 LIM domains) , CMB-23 , testin-2 , testis derived transcript , TES1/TES2 , testin 2 , Testin-like protein , xtes

GENE ID SPECIES
403032 Danio rerio
448383 Xenopus (Silurana) tropicalis
706879 Macaca mulatta
780949 Monodelphis domestica
100126668 Papio anubis
100137158 Nomascus leucogenys
100173774 Pongo abelii
286916 Rattus norvegicus
100407335 Callithrix jacchus
21753 Mus musculus
500040 Rattus norvegicus
26136 Homo sapiens
475293 Canis lupus familiaris
100125376 Sus scrofa
534965 Bos taurus
100137197 Felis catus
395332 Gallus gallus
100071093 Equus caballus
100126564 Oryctolagus cuniculus
100126573 Ovis aries
463669 Pan troglodytes
380398 Xenopus laevis
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