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TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004. Additionally we are shipping and many more products for this protein.
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Human Monoclonal TSSK2 Primary Antibody for ELISA, WB - ABIN565132
Li, Sosnik, Brassard, Reese, Spiridonov, Bates, Johnson, Anguita, Visconti, Salicioni: Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis. in Molecular human reproduction 2010
n vitro phosphorylation experiments carried out with TSKS (show TSKS Antibodies) (isoform 1) fragments revealed particularly strong phosphorylation of a recombinant N-terminal region representing aa 1 (show CRISP2 Antibodies)-150 of TSKS (show TSKS Antibodies), indicating that the N-terminus of human TSKS (show TSKS Antibodies) is phosphorylated by human TSSK2.
Report evolution of testis-specific (show THEG Antibodies) kinases TSSK1B (show TSSK1B Antibodies) and TSSK2 in primates.
Data show that human testis-specific (show THEG Antibodies) serine/threonine (Ser (show SIGLEC1 Antibodies)/Thr (show TRH Antibodies)) kinase (TSSK) 1 (show TSSK1B Antibodies) and 2 messages are expressed exclusively in the testis and suggest that this family of kinases might play a role in sperm function.
HSP90 (show HSP90 Antibodies) function abolished the catalytic activities of TSSK4 (show TSSK4 Antibodies) and -6 but did not significantly alter the specific activities of TSSK1 (show TSSK1B Antibodies) and -2. Inhibition of HSP90 (show HSP90 Antibodies) resulted in increased TSSK ubiquitination and proteasomal degradation
Tssk1 (show TSSK1B Antibodies) and Tssk2 play an important role in the regulation of sperm function.
Results reveal TSSK1 (show TSSK1B Antibodies)- and TSSK2-dependent functions of a transformed chromatoid body in post-meiotic cytodifferentiation of spermatids.
The expression patterns of Tsk2 is documented throughout spermiogenesis showing a late association of Tsk2 with tail-like structures in the lumen of the seminiferous tubule.
SPAG16L can be phosphorylated by TSSK2 in vitro.
Deletion of Tssk2 kinase/substrate pair is predicted to play an indispensable role during spermiogenesis.
TSSK1 (show TSSK1B Antibodies) and TSKS (show TSKS Antibodies) persist in sperm, define a critical role of TSKS (show TSKS Antibodies)' N-terminus in enzyme interaction, identify Ser (show SIGLEC1 Antibodies) 281 as a TSKS (show TSKS Antibodies) phosphorylation site and indicate an indispensable role for TSSK 1 (show TSSK1B Antibodies) and 2 in spermiogenesis.
TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004
testis-specific serine kinase 2
, spermiogenesis associated serine/threonine kinase 22B
, testis-specific serine/threonine-protein kinase 2-like
, diGeorge syndrome protein G
, serine/threonine kinase 22B (spermiogenesis associated)
, serine/threonine-protein kinase 22B
, spermiogenesis associated 2
, testis specific serine threonine kinase 2
, testis-specific kinase 2
, testis-specific serine/threonine-protein kinase 2
, testis specific serine/ threonine kinase 2