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The protein encoded by TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Tetraspanin 2 Proteins (3) and many more products for this protein.
Showing 10 out of 85 products:
Human Polyclonal TSPAN2 Primary Antibody for EIA, WB - ABIN955160
Todd, Doctor, Levy: Sequences and expression of six new members of the tetraspanin/TM4SF family. in Biochimica et biophysica acta 1998
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Human Polyclonal TSPAN2 Primary Antibody for EIA, FACS - ABIN955159
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010
Show all 3 references for 955159
Cow (Bovine) Polyclonal TSPAN2 Primary Antibody for WB - ABIN2782692
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
TSPAN2 may promote apoptosis of RNAKT-15 cells by regulating the JNK (show MAPK8 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway in response to high glucose concentrations. Targeting TSPAN2 could be a potential therapeutic strategy to treat glucose toxicity-induced beta-cell failure.
A novel locus (G allele at rs12122341) at 1p13.2 near TSPAN2 that was associated with large artery atherosclerosis-related stroke.
Studies suggest that TSPAN2 may contribute to the early stages of the oligodendrocyte differentiation into myelin-forming glia. Furthermore, in human lung cancer, Tspan2 could be involved in the progression of the tumour metastasis by modulating cancer cell motility and invasion functions. [review]
TSPAN2 is identified as a factor responsible for invasion, motility, and metastasis.
the C-allele of rs2078371 near TSPAN-2 also reached genome-wide significance for association with migraine.
the activation of astrocytes and microglia was strongly enhanced in Tspan2(null) *Plp1 (show PLP1 Antibodies)(null) double-mutants compared with either single-mutant
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
, tetraspanin 2
, new EST tetraspan 3
, tetraspan NET-3
, tetraspan TM4SF
, tetraspanin 2 isoform