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anti-Thrombospondin 1 (THBS1) Antibodies

The protein encoded by THBS1 is a subunit of a disulfide-linked homotrimeric protein. Additionally we are shipping Thrombospondin 1 Kits (56) and Thrombospondin 1 Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
THBS1 7180 P16562
THBS1 21825  
THBS1 445442  
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Top anti-Thrombospondin 1 Antibodies at

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mammalian Mouse Un-conjugated IF, IHC (p), WB Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. ABIN115004 0.5 mL Log in to see 6 to 8 Days
Cow Mouse Un-conjugated BP, ICC, IF, IHC, IHC (p), IP, Neut, WB Formalin-fixed, paraffin-embedded human placenta stained with Thrombospondin using peroxidase-conjugate and AEC chromogen. Note staining of platelets in the blood vessels. 0.25 mL Log in to see 7 to 9 Days
Cow Mouse Un-conjugated FACS, IF, WB   0.1 mg Log in to see 10 to 12 Days
Cow Mouse Un-conjugated Func, FACS, IF, IP, WB   0.1 mg Log in to see 10 to 12 Days
Human Rabbit Un-conjugated WB Anti- THBS1 Picoband antibody, Western blotting All lanes: Anti THBS1  at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: A431 Whole Cell Lysate at 40ug Lane 4: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 130KD Observed bind size: 190KD 100 μg Log in to see 4 to 6 Days
Human Goat Un-conjugated IHC (p) Formalin-Fixed, Paraffin-Embedded Human Placenta stained with Thrombospondin-1 antibody at 3.75 µg/ml after heat-induced antigen retrieval. Formalin-Fixed, Paraffin-Embedded Human Spleen stained with Thrombospondin-1 antibody at 3.75 µg/ml after heat-induced antigen retrieval. 50 μg Log in to see 6 to 8 Days
Cow Mouse Un-conjugated Func, FACS, IF, WB   0.1 mg Log in to see 10 to 12 Days
Cow Goat Un-conjugated IHC (p) Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
Cow Mouse Un-conjugated IP, WB   0.1 mg Log in to see 10 to 12 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days

THBS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-Thrombospondin 1 Antibodies

  1. Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody for IP, WB - ABIN197629 : Frazier: Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells. in The Journal of cell biology 1987 (PubMed)
    Show all 6 references for ABIN197629

  2. Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody for Func, FACS - ABIN180505 : Galvin, Dixit, ORourke, Santoro, Grant, Frazier: Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing. in The Journal of cell biology 1985 (PubMed)
    Show all 4 references for ABIN180505

  3. Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody for BP, ICC - ABIN151527 : Cupi, Sarra, De Nitto, Franzè, Marafini, Monteleone, Del Vecchio Blanco, Paoluzi, Di Fusco, Gentileschi, Ortenzi, Colantoni, Pallone, Monteleone: Defective expression of scavenger receptors in celiac disease mucosa. in PLoS ONE 2014 (PubMed)
    Show all 4 references for ABIN151527

  4. Mammalian Monoclonal Thrombospondin 1 Primary Antibody for IF, IHC (p) - ABIN115006 : Dixit, Haverstick, ORourke, Hennessy, Grant, Santoro, Frazier: Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin. in Biochemistry 1985 (PubMed)
    Show all 3 references for ABIN115006

  5. Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody for FACS, IF - ABIN180348 : Prater, Plotkin, Jaye, Frazier: The properdin-like type I repeats of human thrombospondin contain a cell attachment site. in The Journal of cell biology 1991 (PubMed)

More Antibodies against Thrombospondin 1 Interaction Partners

Zebrafish Thrombospondin 1 (THBS1) interaction partners

  1. ELL (show ELL Antibodies) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation

Human Thrombospondin 1 (THBS1) interaction partners

  1. Methylation of DAPK (show DAPK1 Antibodies) and THBS1 genes occurs in esophageal gastric-type columnar metaplasia and is associated with H. pylori cagA (show S100A8 Antibodies) positive infection.

  2. Within the limitations of this study, the results seem to sustain the involvement of Pentraxin 3 (show PTX3 Antibodies) and Thrombospondin 1 in the processes of inflammation and angiogenesis in wound healing of patients with postorthodontic gingivectomy.

  3. Results identified CRISP2 (show CRISP2 Antibodies) as a potential binding protein of PSP94 (show MSMB Antibodies) from human sperm.

  4. Circulating TSP-1 levels decrease up to 24 months prior to diagnosis of PDAC and significantly enhance the diagnostic performance of CA19-9. The influence of diabetes mellitus on biomarker behavior should be considered in future studies.

  5. Crisp2 (show CRISP2 Antibodies) genetic defects in sperm from humans and mice result in male infertility.

  6. F-actin dynamics modulate the patterning of TSP1 in extracellular matrix and that TSP1 oligomer state is a key determinant of this process.

  7. TSP-1 regulates multiple microRNAs in VSMCs adding a new layer of complexity to TSP-1 regulation of VSMC function

  8. quercetin could increase TSP-1 expression to inhibit angiogenesis resulting in antagonizing prostate cancer PC-3 (show PCSK1 Antibodies) cell and xenograft tumor growth

  9. The anti-angiogenic activity of the native TSP-1 active fragment was maintained in the new TSP-1 mimetics and the results provide a new chemical approach for the design of TSP-1 mimetics.

  10. In the current study Factor V Leiden (show F5 Antibodies), prothrombin (show F2 Antibodies) G20210A, and thrombospondin-1 polymorphisms showed no association with severity of hepatic fibrosis.

Cow (Bovine) Thrombospondin 1 (THBS1) interaction partners

  1. Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (show THBS2 Antibodies) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (show THBS2 Antibodies), up-regulates expression of FGF2 (fibroblast growth factor 2 (show FGF2 Antibodies)).

  2. Thrombospondin has a role in inducing RhoA (show RHOA Antibodies) inactivation through FAK (show PTK2 Antibodies)-dependent signaling to stimulate focal adhesion disassembly

  3. Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.

  4. Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (show INS Antibodies)-like growth factor

  5. The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications

  6. The novel finding that TSP-1-induced migration is dependent on the CD44 (show CD44 Antibodies) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (show KDM5D Antibodies)).

Mouse (Murine) Thrombospondin 1 (THBS1) interaction partners

  1. Data indicate that thrombospondin-1 may contribute to a destructive macrophage response in dysferlinopathy and pose the intriguing possibility that thrombospondin-1 levels may serve as a biomarker for disease progression.

  2. demonstrate that HIF-2alpha (show EPAS1 Antibodies) is clearly implicated in the TSP1 (show GZMA Antibodies) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction

  3. Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (show TP53 Antibodies) expression or mutational status

  4. Data suggest neutrophil protease- Tsp-1 (thrombospondin-1) axis as a potential antimetastatic therapeutic target.

  5. These results contribute new insights on the controversial role of TSP-1 (show GZMA Antibodies) in cancer.

  6. TSP1 (show GZMA Antibodies) contributes to progression of chronic kidney disease by catalyzing activation of latent TGF-beta1 (show TGFB1 Antibodies), resulting in promotion of a fibroproliferative response over an inflammatory response.

  7. Thrombospondin1 deficiency did not affect the development of obesity associated macro-vascular complication in ApoE (show APOE Antibodies)-/- mice, but attenuated obesity associated micro-vascular complications.

  8. Thrombospondin-1 expression plays a significant role in regulation of migration and adhesion of mononuclear cells, contributing to vascular inflammation during AAA (show AAAS Antibodies) development.

  9. findings prove that the TSP-1 (show GZMA Antibodies)/CD47 (show CD47 Antibodies)/SIRP (show SIRPA Antibodies)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 as a key signal

  10. ADAMTS-7 (show ADAMTS7 Antibodies) was directly associated with thrombospondin-1 by its C terminus and degraded thrombospondin-1 in vivo and in vitro. The inhibitory effect of ADAMTS-7 (show ADAMTS7 Antibodies) on postinjury endothelium recovery was circumvented in Tsp1 (show GZMA Antibodies)(-/-) mice.

Pig (Porcine) Thrombospondin 1 (THBS1) interaction partners

  1. These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (show IGF1 Antibodies) and the mechanisms by which hyperglycemia regulates TSP-1 protein.

  2. Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (show TGFB1 Antibodies) expression.

Thrombospondin 1 (THBS1) Antigen Profile

Protein Summary

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.

Gene names and symbols associated with THBS1

  • thrombospondin 1 (thbs1) antibody
  • thrombospondin 1 (THBS1) antibody
  • thrombospondin 1 (LOC100230636) antibody
  • cysteine-rich secretory protein 2 (CRISP2) antibody
  • thrombospondin 1 (Thbs1) antibody
  • CRISP-2 antibody
  • CT36 antibody
  • GAPDL5 antibody
  • si:dkey-11e23.1 antibody
  • tbsp1 antibody
  • THBS antibody
  • Thbs-1 antibody
  • THBS1 antibody
  • thrombospondin-1 antibody
  • TPX1 antibody
  • TSP antibody
  • TSP-1 antibody
  • Tsp1 antibody
  • wu:fc48c03 antibody

Protein level used designations for THBS1

thrombospondin 1 , thrombospondin-1-like , cancer/testis antigen 36 , glyceraldehyde-3-phosphate dehydrogenase-like 5 , testis specific protein 1 (probe H4-1 p3-1) , testis-specific protein TPX-1 , thrombospondin-1 , thrombospondin-1p180

561901 Danio rerio
453319 Pan troglodytes
705413 Macaca mulatta
100170153 Xenopus (Silurana) tropicalis
100230636 Taeniopygia guttata
100294615 Ovis aries
100390178 Callithrix jacchus
100453386 Pongo abelii
100465724 Ailuropoda melanoleuca
100542373 Meleagris gallopavo
100603886 Nomascus leucogenys
7180 Homo sapiens
281530 Bos taurus
373987 Gallus gallus
7057 Homo sapiens
21825 Mus musculus
445442 Rattus norvegicus
487486 Canis lupus familiaris
100057478 Equus caballus
492313 Sus scrofa
101106433 Ovis aries
100350430 Oryctolagus cuniculus
100727882 Cavia porcellus
379508 Xenopus laevis
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