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Plays a role in transcriptional coactivation (By similarity).. Additionally we are shipping and many more products for this protein.
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Human Polyclonal THRAP3 Primary Antibody for EIA, WB - ABIN955191
Beausoleil, Villén, Gerber, Rush, Gygi: A probability-based approach for high-throughput protein phosphorylation analysis and site localization. in Nature biotechnology 2006
Show all 3 references for ABIN955191
Cow (Bovine) Polyclonal THRAP3 Primary Antibody for WB - ABIN2780648
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
The data suggest a model in which TRAP150 interacts with dimeric PSF (show IGFBP7 Antibodies) to block access of RNA to RRM2 (show RRM2 Antibodies), thereby regulating the activity of PSF (show IGFBP7 Antibodies) toward a broad set of splicing events in T cells.
Thrap3 plays a crucial role in controlling diabetic gene programming and may provide opportunities for the development of new therapeutics for obesity and type 2 diabetes.
BTF (show BCLAF1 Antibodies) has functions distinct from TRAP150 in regulating the subcellular distribution of mRNAs in human cells.
Thrap3 could play indispensable roles in terminal differentiation of adipocytes by enhancing PPARgamma (show PPARG Antibodies)-mediated gene activation cooperatively with Helz2 (show HELZ2 Antibodies).
Data indicate that distinct differences in proteins becoming Poly(ADP-ribose) PARylated upon various genotoxic insults are observed, exemplified by the PARylation of RNA-processing factors THRAP3 and TAF15 (show TAF15 Antibodies) under oxidative stress.
THRAP3 has a rold in the DNA damage response.
TFIID (show TBP Antibodies) and human mediator coactivator (TRAP150) complexes assemble cooperatively on promoter DNA
TRAP150 is a selective coactivator for CLOCK-BMAL1 (show ARNTL Antibodies), promoting its binding to target genes and linking it to the transcriptional machinery at target-gene promoters.
Plays a role in transcriptional coactivation (By similarity).
DNA cross-link repair 1A protein
, DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)
, DNA-crosslink repair gene SNM1
, thyroid hormone receptor associated protein 3
, thyroid hormone receptor-associated protein 3
, thyroid hormone receptor-associated protein complex 150 kDa component
, thyroid hormone receptor-associated protein, 150 kDa subunit