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Involved in the regulation of endosome-to-lysosome trafficking, including endocytic of EGF-EGFR complexes and GABA-A receptors (By similarity).. Additionally we are shipping TRAK1 Antibodies (44) and many more products for this protein.
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This study showed that the TRAK1 was prevalently localized in axons of hippocampal and cortical neurons.
Data suggest that vitamin D receptor (show VDR Proteins) target genes (TRAK1; DUSP10 (show DUSP10 Proteins), dual specificity phosphatase 10 (show DUSP10 Proteins); NRIP1 (show NRIP1 Proteins), nuclear receptor interacting protein 1 (show NRIP1 Proteins); THBD (show THBD Proteins), thrombomodulin (show THBD Proteins)) can be used as markers for individual's response to vitamin D3 supplements.
By mapping and mutating four key sites of GlcNAc addition in hMilton1 (hMilton1Qmut), study demonstrated that Milton is the key and essential substrate through which OGT (show OGT Proteins) inhibits mitochondrial motility.
Details of a robust association of DISC1 (show DISC1 Proteins) with mitochondrial transport complexes containing TRAK1 and Miro1 (show RHOT1 Proteins).
The results of this study established a key role for mammalian TRAK1 proteins in axonal and dendritic targeting of mitochondria.
MGb2 (show SCGB2A1 Proteins)-Ag/TRAK1 may play an important role in the development of colorectal cancer (CRC (show CALR Proteins)) and may be a valuable prognostic indicator of CRC (show CALR Proteins).
GRIF-1 and OIP106 have roles in protein and/or organelle transport in excitable cells in a manner analogous to glutamate receptor-interacting-protein 1 (show GRIP1 Proteins)
Data show that Trak1 interacts with hepatocyte-growth-factor-regulated tyrosine kinase substrate (Hrs), an essential component of the endosomal sorting and trafficking machinery.
TRAK1/MGb2 (show SCGB2A1 Proteins)-Ag is a promising diagnostic marker for gastric cancer and may help to detect signet-ring cell carcinoma and mucinous adenocarcinoma
Our data implicate Trak1 as a crucial regulator of GABA(A) receptor homeostasis and underscore the importance of hyrt mice as a model for studying the molecular etiology of hypertonia associated with human neurological diseases.
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic of EGF-EGFR complexes and GABA-A receptors (By similarity).
trafficking protein, kinesin binding 1
, KIAA1042 protein-like
, 106 kDa O-GlcNAc transferase-interacting protein
, O-linked N-acetylglucosamine transferase interacting protein 106
, OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
, milton homolog 1
, trafficking kinesin-binding protein 1