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Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) Proteins (TFAP2B)

TFAP2B encodes a member of the AP-2 family of transcription factors. Additionally we are shipping TFAP2B Antibodies (54) and TFAP2B Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFAP2B 21419 Q61313
Rat TFAP2B TFAP2B 301285  
TFAP2B 7021 Q92481
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Top TFAP2B Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$3,294.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

TFAP2B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) Interaction Partners

Fruit Fly (Drosophila melanogaster) Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. AP-2beta up-regulates the transcription of the CRYAB (show CRYAB Proteins) gene through stabilizing p53 (show TUBB Proteins).

Cow (Bovine) Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. CVAK104 (show SCYL2 Proteins) binds ATP and functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosphorylation and phosphorylating the beta2-adaptin (show AP2B1 Proteins) subunit of AP2 (show TFAP2A Proteins)

Zebrafish Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. tfap2b and its close relative, tfap2a (show TFAP2A Proteins), play redundant roles in the ectoderm to control skeletogenesis of neural crest cells

Mouse (Murine) Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. the Tfap2a (show TFAP2A Proteins) and Tfap2b transcription factors were identified as two major downstream effectors of Ptf1a (show PTF1A Proteins).

  2. critical roles for AP-2 (show TFAP2A Proteins) activity in retinogenesis, delineating the overlapping expression patterns of Tcfap2a (show TFAP2A Proteins), Tcfap2b, and Tcfap2c in the neural retina, and revealing a redundant requirement for Tcfap2a (show TFAP2A Proteins) and Tcfap2b in horizontal and amacrine cell development

  3. Tfap2b is associated with the development and remodeling of mouse ductus arteriosus and limb patterning.

  4. PKD (show PRKD1 Proteins) is thus a common modulator of the DNA binding activity of AP-2alpha (show TFAP2A Proteins) and AP-2beta through their phosphorylation for negative regulation of the ABCA1 (show ABCA1 Proteins) and adiponectin (show ADIPOQ Proteins) genes expression, respectively.

  5. postprandial activation of PKCmicro plays a role in disordered postprandial adipocytokine expression through AP-2beta.

  6. Whereas AP-2alpha (show TFAP2A Proteins)/beta transcription factors are in vivo not required for the onset or maintenance of noradrenergic differentiation, their essential survival functions are demonstrated for sympathetic progenitors and noradrenergic neurons.

  7. Data suggest that AP-2beta plays critical roles in the epinephrine phenotype and maturation of adrenal chromaffin cells.

  8. Tfap2beta, Et-1 (show EDN1 Proteins), and Hif2alpha (show EPAS1 Proteins) act in a transcriptional network during ductal smooth muscle development. Disruption of this pathway may contribute to patent ductus arteriosus by affecting development of smooth muscle in the ductus arteriosus.

  9. AP-2beta transcriptional factor is a unique regulator of IRS-1 (show IRS1 Proteins) and a candidate gene for insulin (show INS Proteins) resistance.

  10. AP-2beta is a candidate gene for producing adipocyte hypertrophy and may relate to the abnormal characteristics of adipocytes observed in obesity.

Human Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK (show EPHB2 Proteins) and VEGF (show VEGFA Proteins)/PEDF (show SERPINF1 Proteins) signaling.

  2. The AP-2beta polymorphism significantly influenced cognitive performance, whereas the MAOA (show MAOA Proteins) and COMT (show COMT Proteins) polymorphisms did not.

  3. A haploinsufficiency effect of TFAP2B could be involved in familial isolated patent ductus arteriosus.

  4. TFAP2B rs987237 and dietary protein/carbohydrate interacted to modify weight maintenance.

  5. genomic GATA4 (show GATA4 Proteins) and TFAP2B missense mutations may be associated with nonfamilial congenital heart disease with diverse clinical phenotypes in patients with congenital heart disease from southern China

  6. Under energy restriction, TFAP2B may modify the effect of dietary fat intake on weight loss and waist reduction

  7. The findings suggest the lack of involvement of known mutations of TFAP2B with syndromic or nonsyndromic CHDs in Mysore patients

  8. TFAP2B mutation should be considered a risk factor for isolated PDA. However, the detailed genetic mechanism underlying nonsyndromic the PDA-causing TFAP2B mutation is yet to be elucidated.

  9. This study supports a role of the SLC6A4 (show SLC6A4 Proteins), DRD4 (show DRD4 Proteins) and TFAP2B genes in the temperament, including a gene-gene interaction between SLC6A4 (show SLC6A4 Proteins) and TFAP2B. It also provides evidence about an effect of the TFAP2B polymorphism in TFAP2B gene transcription.

  10. central obesity-associated variants in LYPLAL1 (show LYPLAL1 Proteins), NRXN3 (show NRXN3 Proteins), MSRA (show MSRA Proteins), and TFAP2B

Xenopus laevis Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. Expression of TFAP2beta and TFAP2gamma (show TFAP2C Proteins) genes in Xenopus laevis.

Pig (Porcine) Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B) interaction partners

  1. LH and insulin (show INS Proteins) stimulate transcription of -976/+31 bp 5 (show HSPD1 Proteins)'-upstream cis (show CISH Proteins)-acting region of porcine CYP17 (show CYP17A1 Proteins) gene. Maximal transcriptional responsiveness requires proximal Sp1 (show SP1 Proteins) and AP-2-like (show TFAP2D Proteins) sequences -193 to -180 bp 5 (show HSPD1 Proteins)' upstream of transcriptional start site.

  2. Data demonstrates the colocalization of MARK with AP-2 and clathrin, as well as other MARK-interacting proteins such as PAK5.

TFAP2B Protein Profile

Protein Summary

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.

Gene names and symbols associated with TFAP2B

  • Beta Adaptin (Bap)
  • beta-adaptin (Tc00.1047053509799.10)
  • beta-adaptin (Tc00.1047053506247.200)
  • beta-adaptin (LinJ36.0440)
  • beta-adaptin (LbrM35_V2.7120)
  • beta-adaptin (LmjF36.6770)
  • transcription factor AP-2 beta (Tsp_09571)
  • transcription factor AP-2 beta (Tcfap2b)
  • transcription factor AP-2 beta (TFAP2B)
  • transcription factor AP-2 beta (activating enhancer binding protein 2 beta) (TFAP2B)
  • transcription factor AP-2 beta (tfap2b)
  • transcription factor AP-2 beta (Tfap2b)
  • transcription factor AP-2 beta (activating enhancer binding protein 2 beta) (tfap2b)
  • AI606113 protein
  • AP-1beta1 protein
  • AP-2(beta) protein
  • ap-2b protein
  • AP-2beta protein
  • AP-beta1 protein
  • AP1beta1 protein
  • AP2 protein
  • ap2-b protein
  • AP2beta2 protein
  • BAD1 protein
  • bap protein
  • Beta-adaptin protein
  • beta1/2 protein
  • cg12532 protein
  • Dmel\\CG12532 protein
  • E130018K07Rik protein
  • si:dkey-5e16.1 protein
  • Tcfap2b protein
  • TFAP2B protein
  • tfap2beta protein
  • zgc:110163 protein

Protein level used designations for TFAP2B

beta adaptin , CG12532-PA , Bap-PA , beta adaptin drosophila 1 , beta-adaptin , transcription factor AP-2 beta , AP2 transcription factor , activating enhancer-binding protein 2 beta , transcription factor AP-2 beta (activating enhancer binding protein 2 beta) , ap2b , transcription factor AP-2-beta , AP2-beta , activating enhancer-binding protein 2-beta , activating enhancer binding protein 2 beta

GENE ID SPECIES
32987 Drosophila melanogaster
3545690 Trypanosoma cruzi strain CL Brener
3552977 Trypanosoma cruzi strain CL Brener
5073485 Leishmania infantum JPCM5
5420308 Leishmania braziliensis MHOM/BR/75/M2904
5655992 Leishmania major strain Friedlin
10903001 Trichinella spiralis
100313554 Saccoglossus kowalevskii
282381 Bos taurus
462758 Pan troglodytes
707679 Macaca mulatta
100056210 Equus caballus
550545 Danio rerio
21419 Mus musculus
301285 Rattus norvegicus
7021 Homo sapiens
447525 Xenopus laevis
395713 Gallus gallus
403463 Canis lupus familiaris
399526 Sus scrofa
540867 Bos taurus
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