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Transcription Factor CP2 Proteins (TFCP2)

TFCP2 encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. Additionally we are shipping Transcription Factor CP2 Antibodies (51) and Transcription Factor CP2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFCP2 7024 Q12800
TFCP2 21422 Q9ERA0
Rat TFCP2 TFCP2 315309  
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Top Transcription Factor CP2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,406.33
Details
HOST_Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag   10 μg Log in to see 1 to 2 Days
$443.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

TFCP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for Transcription Factor CP2 (TFCP2) Interaction Partners

Human Transcription Factor CP2 (TFCP2) interaction partners

  1. Complement proteins C7 and CFH (show CFH Proteins) control the stemness of liver cancer cells via LSF-1 pathway.

  2. LSF is an important mediator in colorectal carcinoma tumorigenesis and progression, and LSF expression is an important index for and prognostic prediction.

  3. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene (show RAB1A Proteins) addiction to LSF in hepatocellular carcinoma

  4. Secreted OPN (show SPP1 Proteins), induced by LSF, activates c-Met via a potential interaction between OPN (show SPP1 Proteins) and its cell surface receptor CD44 (show CD44 Proteins). A significant correlation was observed among LSF, OPN (show SPP1 Proteins), and activated c-Met levels in HCC (show FAM126A Proteins).

  5. Inhibition of MMP-9 (show MMP9 Proteins) significantly abrogated LSF-induced angiogenesis as well as in vivo tumorigenesis, thus reinforcing the role of MMP-9 (show MMP9 Proteins) in facilitating LSF function.

  6. Data suggest that LSF is a key mediator of the Notch1 (show NOTCH1 Proteins) signaling pathway, suggesting that it might be a novel therapeutic target for the treatment of hepatocellular carcinoma.

  7. Study show that CRTR-1 (show TFCP2L1 Proteins) is generally an activator of transcription (show STAT1 Proteins) and that it modulates the activity of other family members, CP2 (show CP Proteins), NF2d9 (show UBP1 Proteins) and altNF2d9, in a cell specific manner.

  8. SRY (show SRY Proteins) is a hybrid of DGCR8 (show DGCR8 Proteins) and SOX3 (show SOX3 Proteins), and is regulated by the transcription factor CP2.

  9. The expression of osteopontin (OPN (show SPP1 Proteins)), a gene regulating every step in tumor progression and metastasis, was robustly up-regulated by LSF.

  10. The human PcG protein dinG interacts with CP2, a mammalian member of the grainyhead-like family of transcription factors, in vitro and in vivo. The functional consequence of this interaction is repression of CP2-dependent transcription

Mouse (Murine) Transcription Factor CP2 (TFCP2) interaction partners

  1. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene (show RAB1A Proteins) addiction to LSF in hepatocellular carcinoma

  2. present study shows that a transcription factor previously unrelated with epithelial-mesenchymal transition (EMT (show ITK Proteins)), TFCP2c/LSF/LBP-1c, was translocated to the nucleus and bound to the fibronectin (show FN1 Proteins) promoter upon EMT (show ITK Proteins) induction by Snail1 (show SNAI1 Proteins)

  3. the binding of Pin1 (show PIN1 Proteins) at the Thr (show TRH Proteins)-329-Pro-330 motif in LSF permits isomerization by Pin1 (show PIN1 Proteins) of the peptide bonds at the nearby phosphorylated SP motifs (Ser (show SIGLEC1 Proteins)-291 and Ser (show SIGLEC1 Proteins)-309) to the trans configuration, thereby facilitating their dephosphorylation.

  4. CP2 contributes to the pathogenesis of Alzheimer's disease by inducing transferrin (show Tf Proteins) expression via up-regulating its transcription.

  5. CP2 is a major factor in the regulation of globin expression in human and mouse erythroid cells, and CP2 binding to the globin gene promoter is essential for the enhanced transcription of globin genes in erythroid differentiation.

  6. CP2 plays important role during bone development by activating BMP4 (show BMP4 Proteins) transcription

  7. A novel murine splice isoform of CP2, CP2b (show CYP27B1 Proteins), which is identical to CP2a except that it has an additional 36 amino acids encoded by an extra exon was identified and characterized.

  8. findings demonstrate that the APLP2-intracellular C-terminal domains interact with CP2 transcription factor in the nucleus and induce the expression of glycogen synthase kinase 3beta

  9. Results identify LSF as only the second known target (in addition to pRb (show PGR Proteins)) of cyclin C (show CCNC Proteins)/CDK2 (show CDK2 Proteins) activity during progression from quiescence to early G(1).

  10. These data suggest that CP2b (show CYP27B1 Proteins) potentiate erythroid cell-specific alpha-globin (show HBA-A1 Proteins) expression by recruiting CP2c into the nucleus.

Transcription Factor CP2 (TFCP2) Protein Profile

Protein Summary

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease.

Gene names and symbols associated with TFCP2

  • transcription factor CP2 (tfcp2)
  • transcription factor CP2 (TFCP2)
  • transcription factor CP2 (Tfcp2)
  • CP-2 protein
  • CP2 protein
  • D230015P20Rik protein
  • LBP-1c protein
  • LBP-1d protein
  • LBP1 protein
  • LBP1C protein
  • LSF protein
  • LSF1D protein
  • MGC75945 protein
  • SEF protein
  • Tcfcp2 protein
  • TFCP2 protein
  • TFCP2C protein
  • UBP-1 protein

Protein level used designations for TFCP2

transcription factor CP2 , cCP2 transcription factor , SAA3 enhancer factor , alpha-globin transcription factor CP2

GENE ID SPECIES
403094 Xenopus (Silurana) tropicalis
450171 Pan troglodytes
574399 Macaca mulatta
100052504 Equus caballus
100566598 Anolis carolinensis
734497 Xenopus laevis
378900 Gallus gallus
7024 Homo sapiens
477607 Canis lupus familiaris
509448 Bos taurus
21422 Mus musculus
315309 Rattus norvegicus
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