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Transient Receptor Potential Cation Channel, Subfamily C, Member 3 Proteins (TRPC3)

The protein encoded by TRPC3 is a membrane protein that can form a non-selective channel permeable to calcium and other cations. Additionally we are shipping TRPC3 Antibodies (77) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPC3 7222 Q13507
TRPC3 22065  
Rat TRPC3 TRPC3 60395  
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Top TRPC3 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$310.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRPC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) Interaction Partners

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) interaction partners

  1. The subsequent ER stress-induced apoptosis exhibit a strong requirement for constitutive Ca(2+) influx and that TRPC3 contributes to this process.

  2. Data show that mechanical stretching of transient receptor potential cation channel, subfamily C, member 3 (TRPC3) overexpressing fibroblasts induced the activation of nuclear factor-kappa B (NFkappaB).

  3. TRPC3 and TRPC6 (show TRPC6 Proteins) participate diversely in synaptic reorganization in the mossy fiber pathway in temporal lobe epilepsy.

  4. the first in vivo evidence for a proatherogenic role of endothelial TRPC3.

  5. Imin channels are regulated by STIM2 (show Stim2 Proteins), TRPC3-containing INS (show INS Proteins) channels are induced by STIM1 (show STIM1 Proteins), and TRPC1 (show TRPC1 Proteins)-composed Imax channels are activated by both STIM1 (show STIM1 Proteins) and STIM2 (show Stim2 Proteins).

  6. CaSR (show CASR Proteins) activation mediates Ca2 (show CA2 Proteins)+ influx and cell proliferation via TRPC3 and TRPC6 (show TRPC6 Proteins) in human mesangial cells

  7. although gene deletion of TRPC3 or TRPC6 (show TRPC6 Proteins) alone did not protect against hypertrophy or dysfunction from pressure overload, combined deletion was protective, supporting the value of dual inhibition

  8. there is an absolute requirement for TRPC3-mediated diacylglycerol-dependent Ca(2 (show CA2 Proteins)+) entry to initiate and sustain the spiking response.

  9. Removal of a large hydrophobic residue (I667A or I667E) generated TRPC3 channels with approximately 60% constitutive activity, suggesting I667 as part of the dynamic structure occluding the permeation path.

  10. These data emphasize the role of TRPC3 and Ca(2 (show CA2 Proteins)+) influx in the regulation of BDNF (show BDNF Proteins) secretion by human airway smooth muscle.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) interaction partners

  1. Data show that mechanical stretching of transient receptor potential cation channel, subfamily C, member 3 (TRPC3) overexpressing fibroblasts induced the activation of nuclear factor-kappa B (NFkappaB).

  2. TRPC3 and TRPC6 (show TRPC6 Proteins) participate diversely in synaptic reorganization in the mossy fiber pathway in temporal lobe epilepsy.

  3. May activate TRPC3 channels to cause extracellular Ca(2 (show CA2 Proteins)+) influx.

  4. These findings provide the first mechanistic insights into the TRPC3- dependent mechanisms, by which activated calcium signaling is coupled to lipid metabolismand the regulation of Purkinje cell development in the Mwk cerebellum.

  5. study suggested that TRPC3 can modulate sperm function via mobilization of sperm [Ca(2 (show CA2 Proteins)+)]i

  6. TRPC3-NCX (show SLC8A1 Proteins) micro/nanodomain communication as determinant of cardiac contractility and susceptibility to arrhythmogenic stimuli.

  7. the TRPC3 channel is involved in agonist-induced vasoconstriction and plays important role in NO-mediated vasorelaxation of intact mesenteric arteries.

  8. TRPC3 channels are present in renal fibroblasts and control fibroblast proliferation, differentiation, and activation through Ca(2 (show CA2 Proteins)+)-mediated ERK (show EPHB2 Proteins) signaling.

  9. Ca(2+) transients in skeletal muscle are regulated via interaction between Mg29 and TRPC3.

  10. TRPC3 regulates SKCa channel activation through receptor-dependent trafficking to the plasma membrane, where it provides the source of Ca(2 (show CA2 Proteins)+) influx for sustained SKCa channel activation, EC hyperpolarization, and endothelium-dependent vasodilation.

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) interaction partners

  1. Demonstrate that Ca(2+) entry via endothelial TRPC3 contributes to nitric oxide release and have revealed that hypoxia-reoxygenation is associated with inhibition of TRPC3 activity.

  2. Study determined the sequence of pig TRPC1 and TRPC3-7 channels and found pig TRPC cDNAs resemble their human homologs more than the others .

  3. heteromeric cation channels comprised of the TRPP2 mutant and the TRPC3 or TRPC7 (show TRPM2 Proteins) protein induce enhanced receptor-activated Ca(2 (show CA2 Proteins)+) influx that may lead to dysregulated cell growth in ADPKD

TRPC3 Protein Profile

Protein Summary

The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TRPC3

  • transient receptor potential cation channel, subfamily C, member 3 (TRPC3)
  • transient receptor potential cation channel, subfamily C, member 3 (Trpc3)
  • Mwk protein
  • Trcp3 protein
  • Trp3 protein
  • Trpc3 protein
  • TrpC3c protein
  • Trrp3 protein

Protein level used designations for TRPC3

transient receptor potential cation channel, subfamily C, member 3 , short transient receptor potential channel 3-like , short transient receptor potential channel 3 , hTrp-3 , transient receptor protein 3 , TRP-3 , mTrp3 , receptor-activated cation channel TRP3 , trp-related protein 3 , ion channel protein , transient receptor potential cation channel subfamily C member 3 , oocyte transient receptor potential channel

GENE ID SPECIES
100072204 Equus caballus
428766 Gallus gallus
471294 Pan troglodytes
100135636 Cavia porcellus
100454158 Pongo abelii
100483524 Ailuropoda melanoleuca
7222 Homo sapiens
22065 Mus musculus
60395 Rattus norvegicus
483844 Canis lupus familiaris
397210 Sus scrofa
286866 Bos taurus
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