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The protein encoded by TOMM22 is an integral membrane protein of the mitochondrial outer membrane. Additionally we are shipping Translocase of Outer Mitochondrial Membrane 22 Homolog (Yeast) Antibodies (28) and Translocase of Outer Mitochondrial Membrane 22 Homolog (Yeast) Kits (15) and many more products for this protein.
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The specificity and reversibility of hepatocyte ablation after temporary knockdown of Tomm22 provides an additional model to study liver regeneration, under conditions where most hepatocytes have died.
Tom22 is essential for metabolic conversion, as its knockdown by small interfering RNA (siRNA) completely ablated progesterone conversion in both steroidogenic mouse Leydig MA-10 and human adrenal NCI cells.
Blockade of mitochondrial protein (show COX6B2 Proteins) import triggers the recruitment of PARK2 (show PARK2 Proteins), by PINK1 (show PINK1 Proteins), to the TOMM machinery.
Studies indicate that PUMA (show BBC3 Proteins) and TOMM22 as potential targets for miRNA-BART (show BSND Proteins) viral transcripts.
The interaction with the cytosolic domain of Tom22 helps Bax (show BAX Proteins) to acquire a conformation able to interact with the outer mitochondrial membrane.
Levels of Tom22 in mitochondria accelerate the rate of Tom7 (show TOMM7 Proteins) assembly into the mature TOM complex.
the cytosolic domains of Tom20 (show TOMM20 Proteins) and Tom22 function to maintain their substrate preproteins unfolded and prevent them from aggregating on the mitochondrial surface
We have identified TOM22, a component of the translocase of the outer mitochondrial membrane (TOM), as a mitochondrial receptor of Bax (show BAX Proteins).
Data demonstrate that LktA interacts with the Tom22 and Tom40 (show TOMM40 Proteins) components of the translocase of the outer mitochondrial membrane (TOM), which suggests that import of this toxin into mitochondria involves a classical import pathway for endogenous proteins.
The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.
mitochondrial import receptor Tom22
, mitochondrial import receptor subunit TOM22 homolog
, translocase of outer mitochondrial membrane 22 homolog (yeast)
, translocase of outer membrane 22 kDa subunit homolog
, Translocase of outer membrane 22 kDa subunit homolog