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anti-Transmembrane Channel-Like 6 (TMC6) Antibodies

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. Additionally we are shipping Transmembrane Channel-Like 6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMC6 11322 Q7Z403
TMC6 217353 Q7TN60
TMC6    
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Top anti-Transmembrane Channel-Like 6 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 μg/ml. Western blot analysis of EVER1 in A-20 cell lysate with AP30321PU-N EVER1 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 μg/ml. Western blot analysis of EVER1 in human spleen tissue lysate with AP30322PU-N EVER1 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB TMC6 Antibody (N-term) (ABIN658133) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the TMC6 antibody detected the TMC6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Testis (formalin-fixed, paraffin-embedded) stained with TMC6 antibody ABIN343905 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Mouse Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Mouse Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details

TMC6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Transmembrane Channel-Like 6 Antibodies

  1. Human Polyclonal TMC6 Primary Antibody for IHC, WB - ABIN351053 : Kurima, Yang, Sorber, Griffith: Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. in Genomics 2003 (PubMed)
    Show all 5 references for ABIN351053

  2. Human Polyclonal TMC6 Primary Antibody for IHC, WB - ABIN351052 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)
    Show all 5 references for ABIN351052

  3. Human Polyclonal TMC6 Primary Antibody for EIA, IHC (p) - ABIN499808 : Majewski, Jab?o?ska, Orth: Epidermodysplasia verruciformis. Immunological and nonimmunological surveillance mechanisms: role in tumor progression. in Clinics in dermatology 1997 (PubMed)
    Show all 4 references for ABIN499808

  4. Human Polyclonal TMC6 Primary Antibody for EIA, IHC (p) - ABIN499806 : Keresztes, Mutai, Heller: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins. in BMC genomics 2003 (PubMed)
    Show all 4 references for ABIN499806

  5. Mouse (Murine) Polyclonal TMC6 Primary Antibody for IHC, WB - ABIN350032 : Carninci, Kasukawa, Katayama, Gough, Frith, Maeda, Oyama, Ravasi, Lenhard, Wells, Kodzius, Shimokawa, Bajic, Brenner, Batalov, Forrest, Zavolan, Davis, Wilming, Aidinis, Allen, Ambesi-Impiombato et al.: The transcriptional landscape of the mammalian genome. ... in Science (New York, N.Y.) 2005 (PubMed)
    Show all 3 references for ABIN350032

More Antibodies against Transmembrane Channel-Like 6 Interaction Partners

Human Transmembrane Channel-Like 6 (TMC6) interaction partners

  1. Findings suggest that SNP in EVER 1 may be involved in the development of premalignant skin lesions that harbour beta-HPV, perhaps giving rise to SCC (show CYP11A1 Antibodies) tumours that have lost beta-HPV gene expression during progression

  2. TMC6/EVER1 and TMC8/EVER2 (show TMC8 Antibodies) are known to be involved in the development of EV.

  3. TMC6 variants are associated with diminished age-of-onset of P. aeruginosa airway infection in children with cystic fibrosis (show S100A8 Antibodies).

  4. EV is also a rare autosomal recessive genodermatosis involving susceptibility to human papillomavirus (HPV) infections and squamous cell carcinoma, caused in most cases by homozygous mutations in EVER1 or EVER2 (show TMC8 Antibodies).

  5. Expression of both EVER1 and EVER2 (show TMC8 Antibodies) in B cells is activated immediately after Epstein-Barr virus (EBV) infection, whereas at later stages, it is strongly repressed by latent membrane protein 1-activated NF-kappaB (show NFKB1 Antibodies) signaling.

  6. Data support the involvement of the TMC6/8 region in cervix cancer susceptibility.

  7. Mutations in EVER1 are associated with epidermodysplasia verruciformis.

  8. four mutations in recurrent respiratory papillomatosis patients might indicate that EVER 1 alleles are not associated with susceptibility to RRP (show RRBP1 Antibodies)

  9. The growing number of mutations in epidermodysplasia verruciformis (EV) pedigrees supports the hypothesis that EVER1 and EVER2 (show TMC8 Antibodies) are the molecular basis of EV.

  10. HPV16 E5 protein binds to EVER and ZnT-1 (show SLC30A1 Antibodies) and blocks their negative regulation

Transmembrane Channel-Like 6 (TMC6) Antigen Profile

Protein Summary

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Gene names and symbols associated with TMC6

  • transmembrane channel-like 6 (TMC6) antibody
  • transmembrane channel-like 6b (tmc6b) antibody
  • transmembrane channel-like 6 (tmc6) antibody
  • transmembrane channel-like 6 (LOC100218212) antibody
  • transmembrane channel-like gene family 6 (Tmc6) antibody
  • D11Ertd204e antibody
  • EV1 antibody
  • ever1 antibody
  • EVIN1 antibody
  • LAK-4P antibody
  • MGC83549 antibody
  • zgc:92610 antibody

Protein level used designations for TMC6

transmembrane channel-like 6 , epidermodysplasia verruciformis 1 , transmembrane channel-like protein 6 , transmembrane channel-like protein 6-like , epidermodysplasia verruciformis protein 1 , expressed in activated T/LAK lymphocytes , protein LAK-4

GENE ID SPECIES
422089 Gallus gallus
436978 Danio rerio
483341 Canis lupus familiaris
505575 Bos taurus
444078 Xenopus laevis
100058089 Equus caballus
100218212 Taeniopygia guttata
100380197 Xenopus (Silurana) tropicalis
100443349 Pongo abelii
100546520 Meleagris gallopavo
100597507 Nomascus leucogenys
11322 Homo sapiens
217353 Mus musculus
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