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anti-Transmembrane Protein 70 (TMM70) Antibodies

TMM70 likely encodes a mitochondrial membrane protein. Additionally we are shipping Transmembrane Protein 70 Proteins (3) and Transmembrane Protein 70 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMM70 54968 Q9BUB7
TMM70 70397 Q921N7
TMM70 500384  
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Top anti-Transmembrane Protein 70 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB TMM70 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TMM70 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. TMM70 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the TMM70 antibody detected the TMM70 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB TMM70 Antibody (C-term)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TMM70 antibody detected the TMM70 protein (arrow). TMM70 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMM70 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

TMM70 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Transmembrane Protein 70 Antibodies

  1. Human Polyclonal TMM70 Primary Antibody for EIA, IHC (p) - ABIN955257 : Karasik, Hsu, Zhou, Cupples, Kiel, Demissie: Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 (PubMed)
    Show all 5 references for ABIN955257

  2. Human Polyclonal TMM70 Primary Antibody for EIA, IHC (p) - ABIN500988 : Cízková, Stránecký, Mayr, Tesarová, Havlícková, Paul, Ivánek, Kuss, Hansíková, Kaplanová, Vrbacký, Hartmannová, Nosková, Honzík, Drahota, Magner, Hejzlarová, Sperl, Zeman, Houstek, Kmoch: TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy. in Nature genetics 2008 (PubMed)

More Antibodies against Transmembrane Protein 70 Interaction Partners

Human Transmembrane Protein 70 (TMM70) interaction partners

  1. In summary, TMEM70 mutations can cause distinct ultrastructural mitochondrial degeneration and almost complete deficiency of ATP synthase but are still amenable to treatment.

  2. TMEM70 deficiency is a panethnic, multisystemic disease with variable outcome depending mainly on adequate management of hyperammonaemic crises in the neonatal period and early childhood.

  3. Pulmonary hypertension has rarely been reported in mitochondrial disorders and, so far, it has been described in association with TMEM70 deficiency only in one patient

  4. These data indicate that the biological function of TMEM70 in the ATP synthase biogenesis may be mediated through interaction with other protein(s).

  5. this study suggests that mutant TMEM70 associates in high molecular weight complexes (470-550 kDa) when expressed in Hela cells and exerts a direct action in ATP synthase biogenesis and assembly, mediating the incorporation of F1 moieties.

  6. Fibroblasts from 10 patients with TMEM70 317-2A>G homozygous mutation showed a significant 82-89% decrease of ATP synthase and 50-162% increase of respiratory chain complex IV and 22-53% increase of complex III.

  7. The authors report a fragmented mitochondrial network and swollen and irregularly shaped mitochondria with partial to complete loss of the cristae in fibroblasts of a patient with a novel TMEM70 gene deletion.

  8. TMEM70 mutations are involved in the pathogenesis of 3-methylglutaconic acid (3-MGA (show AGLU Antibodies)) acydoses in populations of different ethnic origin and become a useful genetic marker for this disease.

  9. The study identifies TMEM70 gene defect as a pan (show SUPT6H Antibodies)-ethnic disorder and further redefines it as the most common cause of nuclear-origin ATP synthase deficiency.

  10. Complex V TMEM70 deficiency results in mitochondrial nucleoid disorganization.

Transmembrane Protein 70 (TMM70) Antigen Profile

Protein Summary

This gene likely encodes a mitochondrial membrane protein. The encoded protein may play a role in biogenesis of mitochondrial ATP synthase. Mutations in this gene have been associated with neonatal mitochondrial encephalocardiomyopathy due to ATP synthase deficiency. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with TMM70

  • transmembrane protein 70 (TMEM70) antibody
  • transmembrane protein 70 (Tmem70) antibody
  • 1110020A09Rik antibody
  • 2210416J16Rik antibody
  • MC5DN2 antibody
  • RGD1566224 antibody

Protein level used designations for TMM70

transmembrane protein 70, mitochondrial

GENE ID SPECIES
54968 Homo sapiens
70397 Mus musculus
500384 Rattus norvegicus
613774 Bos taurus
420188 Gallus gallus
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