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Transportin 2 Proteins (TNPO2)

Probably functions in nuclear protein import as nuclear transport receptor. Additionally we are shipping Transportin 2 Antibodies (16) and Transportin 2 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNPO2 30000 O14787
Rat TNPO2 TNPO2 304670  
TNPO2 212999 Q99LG2
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Top Transportin 2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TNPO2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Transportin 2 (TNPO2) Interaction Partners

Human Transportin 2 (TNPO2) interaction partners

  1. IPO3 (show SLAMF1 Proteins) binds NEMO (show IKBKG Proteins), promotes its nuclear import, and is critical for DNA damage-dependent NF-kappaB (show NFKB1 Proteins) activation.

  2. Studies indicate potential roles of Tranportin-1 and Transportin-2 beyond protein nuclear import.

  3. a role for the nuclear trafficking factor TRN2 (transportin 2) through HuR (show ELAVL1 Proteins) in cell death

  4. Nuclear import of fused in sarcoma (FUS (show FUS Proteins)) is dependent on Transportin, and interference with this transport pathway leads to cytoplasmic redistribution and recruitment of fused in sarcoma (FUS (show FUS Proteins)) into stress granules.

  5. Karyopherin beta 2B participates in mRNA export from the nucleus

  6. Transportin-2 mediates nuclear import of HuR (show ELAVL1 Proteins) protein in vitro

  7. The structure of Kap (show CDKN3 Proteins) beta 2 (also known as Transportin) bound to one of its substrates, the NLS (show ALDH1A2 Proteins) of hnRNP A1 (show HNRNPA1 Proteins), that we report here explains the mechanism of substrate displacement by Ran GTPase (show RAN Proteins).

Mouse (Murine) Transportin 2 (TNPO2) interaction partners

  1. Early in muscle differentiation, HuR (show ELAVL1 Proteins) is localized to the nucleus of myoblasts by active Transportin 2 (TRN2)-mediated import.

Transportin 2 (TNPO2) Protein Profile

Protein Summary

Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).

Gene names and symbols associated with Transportin 2 Proteins (TNPO2)

  • transportin 2 (TNPO2)
  • transportin 2 (tnpo2)
  • transportin 2 (Tnpo2)
  • transportin 2 (importin 3, karyopherin beta 2b) (tnpo2)
  • transportin 2 (importin 3, karyopherin beta 2b) (Tnpo2)
  • 1110034O24Rik protein
  • AA414969 protein
  • AI464345 protein
  • AI852433 protein
  • ik:tdsubc_2a7 protein
  • IPO3 protein
  • Knpb2b protein
  • Kpnb2b protein
  • tdsubc_2a7 protein
  • TNPO2 protein
  • TRN2 protein
  • wu:fb01c02 protein
  • wu:fe01f03 protein
  • wu:fe16e12 protein
  • xx:tdsubc_2a7 protein
  • zgc:101009 protein

Protein level used designations for Transportin 2 Proteins (TNPO2)

transportin 2 , transportin 2 (importin 3, karyopherin beta 2b) , importin 3 , karyopherin beta 2b, transportin , karyopherin beta-2b , transportin-2 , fb01c02 , fe01f03 , karyopherin (importin) beta 2b

GENE ID SPECIES
455748 Pan troglodytes
484930 Canis lupus familiaris
100080159 Ornithorhynchus anatinus
495499 Xenopus laevis
30000 Homo sapiens
504589 Bos taurus
304670 Rattus norvegicus
100519078 Sus scrofa
100716905 Cavia porcellus
445499 Danio rerio
212999 Mus musculus
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