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May function as transcription repressor\; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. Additionally we are shipping and many more products for this protein.
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Human Polyclonal TRIM66 Primary Antibody for IF, IHC (p) - ABIN5590163
Zhu, Li, Yang, Tian, Wang, Yuan, Dong, He, Wang, Li: Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation. in Scientific reports 2016
TRIM66 may act as an oncogene (show RAB1A Antibodies) through suppressing apoptosis pathway and promoting TGF-beta (show TGFB1 Antibodies) signaling in osteosarcoma carcinogenesis. TRIM66 may be a prognostic factor and potential therapeutic target in osteosarcoma.
Data suggest a role for transcriptional intermediary factor 1 (TIF1 (show TRIM24 Antibodies)) delta in heterochromatin-mediated gene silencing during postmeiotic phases of spermatogenesis.
May function as transcription repressor\; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity).
tripartite motif containing 66
, tripartite motif-containing 66
, transcriptional intermediary factor 1 delta
, tripartite motif-containing protein 66