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Troponin I Type 2 (Skeletal, Fast) Proteins (TNNI2)

TNNI2 encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. Additionally we are shipping Troponin I Type 2 (Skeletal, Fast) Antibodies (95) and Troponin I Type 2 (Skeletal, Fast) Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNNI2 7136 P48788
TNNI2 29389 P27768
TNNI2 21953 P13412
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Top Troponin I Type 2 (Skeletal, Fast) Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$413.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

TNNI2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced Troponin I Type 2 (Skeletal, Fast) Proteins

  1. Human TNNI2 Protein expressed in Escherichia coli (E. coli) - ABIN1098700 : Ausoni, Campione, Picard, Moretti, Vitadello, De Nardi, Schiaffino: Structure and regulation of the mouse cardiac troponin I gene. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN1098700

More Proteins for Troponin I Type 2 (Skeletal, Fast) (TNNI2) Interaction Partners

Human Troponin I Type 2 (Skeletal, Fast) (TNNI2) interaction partners

  1. TNNI2 gene missense mutation is associated with distal arthrogryposis type 1.

  2. report the first TNNI2 mutation in classical FSS and describe an atypical adult FSS case with only facial contractures resulting from somatic mosaicism

  3. Molecular genetic investigations revealed pathogenic mutations in MYH3 (show MYH3 Proteins), TPM2 (show TPM2 Proteins), and TNNI2 in one sporadic and 19 familial cases of distal arthrogryposis.

  4. Atrial re-expression of ssTnI (show TNNI1 Proteins) during paroxysmal atrial fibrillation in patients does not seem to be part of the process of AF-associated cardiomyocyte dedifferentiation but seems to result from transient cardiomyocyte stress at the onset of AF.

  5. study found a novel TNNI2 mutation in a Chinese family with distal arthrogryposis type 2B

  6. Implantation of stable human clone expressing fast-twitch skeletal muscle troponin I in female BALB/c nude mice inhibits primary tumor growth and suggests that grafts are self-inhibitory by halting angiogenesis.

  7. These findings reveal a new function for TNNI2 as a co-activator of ERRalpha (show ESRRA Proteins).

  8. Gene expression revealed up-regulation of pro-angiogenic (PGF (show PGF Proteins)), anti-apoptotics (BAG-1 (show BAG1 Proteins), BCL-2 (show BCL2 Proteins)), heart development (TNNT2 (show TNNT2 Proteins), TNNC1 (show TNNC1 Proteins)) and extracellular matrix remodelling (MMP-2 (show MMP2 Proteins), MMP-7 (show MMP7 Proteins)) genes in SM.

Pig (Porcine) Troponin I Type 2 (Skeletal, Fast) (TNNI2) interaction partners

  1. analysis of expression profiling of porcine troponin I family in three different types of muscles during development

  2. Two novel single nucleotide polymorphisms (EU743939:g.5174T>C in intron 4 and EU743939:g.8350C>A in intron 7) in TNNI1 (show TNNI1 Proteins) and one SNP (EU696779:g.1167C>T in intron 3) in TNNI2 were identified.

  3. Three polymorphisms in TNNI1 (show TNNI1 Proteins) and TNNI2 genes are associated with meat quality traits.

Rabbit Troponin I Type 2 (Skeletal, Fast) (TNNI2) interaction partners

Mouse (Murine) Troponin I Type 2 (Skeletal, Fast) (TNNI2) interaction partners

  1. our findings revealed a new function of tnni2 in the regulation of bone development, and the study of gain-of-function mutation in Tnni2 in transgenic mice opens a new avenue to understand the pathological mechanism of human DA2B (show TPM2 Proteins) disorder.

Zebrafish Troponin I Type 2 (Skeletal, Fast) (TNNI2) interaction partners

  1. Data show thattnni1 and tnni2 transcripts were not detectable in the somites until 16 h post-fertilization (hpf), after which they were identified as slow-and fast muscle-specific (show EIF3K Proteins), respectively.

Troponin I Type 2 (Skeletal, Fast) (TNNI2) Protein Profile

Protein Summary

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with TNNI2

  • troponin I type 2 (skeletal, fast) (TNNI2)
  • troponin I type 2 (skeletal, fast) (Tnni2)
  • troponin I, fast skeletal muscle-like (TNNI2)
  • troponin I, skeletal, fast 2 (Tnni2)
  • troponin I, skeletal, fast 2a, tandem duplicate 4 (tnni2a.4)
  • AMCD2B protein
  • DA2B protein
  • FSSV protein
  • fsTnI protein
  • hm:zehn0173 protein
  • TNI protein
  • TnI-F4 protein
  • tnni2 protein
  • tropI-1d protein
  • zgc:86800 protein

Protein level used designations for TNNI2

fast-twitch skeletal muscle troponin I , troponin I fast twitch 2 , troponin I, fast skeletal muscle , troponin I, fast-twitch isoform , troponin I, fast-twitch skeletal muscle isoform , troponin I, skeletal, fast , troponin I fast-twitch skeletal isoform , troponin 1, type 2 , troponin I, skeletal, fast 2 , sTnI protein (aa 85-182) , fast muscle troponin I , troponin I type 2 (skeletal, fast) , troponin I, skeletal, fast 2a.4

GENE ID SPECIES
7136 Homo sapiens
606751 Sus scrofa
100009581 Oryctolagus cuniculus
29389 Rattus norvegicus
396386 Gallus gallus
790768 Bos taurus
21953 Mus musculus
494164 Danio rerio
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