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anti-Troponin T2, Cardiac (TNNT2) Antibodies

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Additionally we are shipping Cardiac Troponin T2 Kits (71) and Cardiac Troponin T2 Proteins (35) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top anti-Cardiac Troponin T2 Antibodies at antibodies-online.com

Showing 10 out of 281 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse Un-conjugated IF, IHC (p) 0.1 mg Log in to see 10 to 12 Days
$519.75
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cat Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cat Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cow Mouse Un-conjugated EIA, WB   0.2 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, IHC (p) 0.25 mg Log in to see 6 to 8 Days
$500.50
Details
Rabbit Mouse Un-conjugated IF, IHC (p) 250 μL Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated EIA, WB 0.2 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mL Log in to see 6 to 8 Days
$423.50
Details

TNNT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Cardiac Troponin T2 Antibodies

  1. Human Polyclonal Cardiac Troponin T2 Primary Antibody for EIA, WB - ABIN951043 : Millat, Chanavat, Créhalet, Rousson: Development of a high resolution melting method for the detection of genetic variations in hypertrophic cardiomyopathy. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 3 references for ABIN951043

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for IF, IHC (p) - ABIN180606 : Malouf, McMahon, Oakeley, Anderson: A cardiac troponin T epitope conserved across phyla. in The Journal of biological chemistry 1992 (PubMed)

  3. Chicken Polyclonal Cardiac Troponin T2 Primary Antibody for WB - ABIN2776953 : Klaassen, Probst, Oechslin, Gerull, Krings, Schuler, Greutmann, Hürlimann, Yegitbasi, Pons, Gramlich, Drenckhahn, Heuser, Berger, Jenni, Thierfelder: Mutations in sarcomere protein genes in left ventricular noncompaction. in Circulation 2008 (PubMed)

  4. Human Monoclonal Cardiac Troponin T2 Primary Antibody for EIA, FACS - ABIN1105666 : Hershberger, Pinto, Parks, Kushner, Li, Ludwigsen, Cowan, Morales, Parvatiyar, Potter: Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. in Circulation. Cardiovascular genetics 2009 (PubMed)

More Antibodies against Cardiac Troponin T2 Interaction Partners

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. sensitivity and specificity of cardiac specific troponin T levels in detecting cardiac damage are much higher according to telecardiography and electrocardiography

  2. since hs-cTnT levels of non-AMI patients can be over the diagnostic cut-off value, further studies are necessary to define clinically applicable cut-off values of hs-cTnT

  3. Data indicate that cardiac troponin T (cTn (show CALCA Antibodies)) timing was comparable between the urban university maximum care and the rural regional primary care facility.

  4. Troponin T velocity can be used for early risk stratification of patients with increased risk for cardiac mortality.

  5. hs-cTnT may be a more useful marker than cTnI (show TNNI3 Antibodies) to detect peri (show PLIN1 Antibodies)-operative myocardial apoptosis and injury during coronary artery bypass grafting with cardiopulmonary bypass.

  6. Hs-cTnT was independently associated with LV dysfunction and LV hypertrophy assessed with MPI (show MPI Antibodies) in newly diagnosed hypertensive patients.

  7. In patients with acute ischemic stroke, troponin T levels were elevated compared to controls.

  8. In patients with stable angina, the presence and extent of coronary atherosclerosis is related with circulating levels of hs-cTnT, also in the absence of ischemia, suggesting an ischemia-independent mechanism of hs-cTnT release.

  9. Increased hs-cTnT levels occur in 30% of female patients after TOF (show FEZF2 Antibodies) repair, and are associated with greater RV volumes and worse RV EF.

  10. Three homologous genes have evolved in vertebrates to encode three muscle type-specific TnT isoforms: TNNT1 for slow skeletal muscle TnT, TNNT2 for cardiac muscle TnT, and TNNT3 for fast skeletal muscle TnT.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2 (show CA2 Antibodies)+-sensitivity, structure and kinetics are brought about through PKC (show PKC Antibodies) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  2. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  3. TnT (show TNNI1 Antibodies) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (show MYH6 Antibodies) and hypertrophic cardiomyopathy in the presence of MYH7 (show MYH7 Antibodies).

  4. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

  5. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  6. Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T.

  7. Study is the first to show that the interplay between the N terminus of cTnT and the overlapping ends of contiguous Tm effectuates different states of Tm on the actin filament.

  8. We conclude that the observed clinical severity of the cTnT Delta160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca(2 (show CA2 Antibodies)+) homeostasis

  9. Report two distinct functional regions within the N-terminus of cTnT with divergent roles in mediating cardiac contractile activation.

  10. Data show that cardiac TnI (show TNNI2 Antibodies) gene transition and the alternatively spliced cardiac TnT isoform switching occur in postnatal pulmonary vein.

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (show TNNI1 Antibodies), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (show TPM2 Antibodies)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (show TNNI1 Antibodies) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Antigen Profile

Protein Summary

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with TNNT2

  • troponin T type 2 (cardiac) (TNNT2) antibody
  • troponin T2, cardiac (Tnnt2) antibody
  • troponin T type 2 (cardiac) (Tnnt2) antibody
  • troponin T type 2 (cardiac) (tnnt2) antibody
  • troponin T2a, cardiac (tnnt2a) antibody
  • CMH2 antibody
  • CMPD2 antibody
  • CT3 antibody
  • cTnT antibody
  • Ctt antibody
  • CTTG antibody
  • LVNC6 antibody
  • RATCTTG antibody
  • RCM3 antibody
  • tnnt2 antibody
  • Tnnt3 antibody
  • Tnt antibody
  • TnTC antibody

Protein level used designations for TNNT2

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPECIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
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