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anti-Troponin T2, Cardiac (TNNT2) Antibodies

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Additionally we are shipping Cardiac Troponin T2 Kits (69) and Cardiac Troponin T2 Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
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Top anti-Cardiac Troponin T2 Antibodies at antibodies-online.com

Showing 10 out of 390 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse Un-conjugated IF, IHC (p) 0.1 mg Log in to see 10 to 12 Days
$519.75
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cat Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cat Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cow Mouse Un-conjugated EIA, WB   0.2 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, IHC (p) 0.25 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IA, WB   0.2 mg Log in to see 5 to 7 Days
$278.25
Details
Human Mouse Un-conjugated EIA, WB 0.2 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mL Log in to see 6 to 8 Days
$423.50
Details

TNNT2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Cardiac Troponin T2 Antibodies

  1. Human Polyclonal Cardiac Troponin T2 Primary Antibody for EIA, WB - ABIN951043 : Millat, Chanavat, Créhalet, Rousson: Development of a high resolution melting method for the detection of genetic variations in hypertrophic cardiomyopathy. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 3 references for ABIN951043

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for IF, IHC (p) - ABIN180606 : Malouf, McMahon, Oakeley, Anderson: A cardiac troponin T epitope conserved across phyla. in The Journal of biological chemistry 1992 (PubMed)

  3. Chicken Polyclonal Cardiac Troponin T2 Primary Antibody for WB - ABIN2776953 : Klaassen, Probst, Oechslin, Gerull, Krings, Schuler, Greutmann, Hürlimann, Yegitbasi, Pons, Gramlich, Drenckhahn, Heuser, Berger, Jenni, Thierfelder: Mutations in sarcomere protein genes in left ventricular noncompaction. in Circulation 2008 (PubMed)

  4. Human Monoclonal Cardiac Troponin T2 Primary Antibody for EIA, FACS - ABIN1105666 : Hershberger, Pinto, Parks, Kushner, Li, Ludwigsen, Cowan, Morales, Parvatiyar, Potter: Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. in Circulation. Cardiovascular genetics 2009 (PubMed)

  5. Human Monoclonal Cardiac Troponin T2 Primary Antibody for IA, WB - ABIN265695 : Qiao, Tang, Munske, Dutta, Ivory, Dong: Enhanced fluorescence anisotropy assay for human cardiac troponin I and T detection. in Journal of fluorescence 2011 (PubMed)

More Antibodies against Cardiac Troponin T2 Interaction Partners

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. Discordant elevation of cTnT in the presence of normal CK plasma levels on admission is associated with increased mortality in STEMI patients undergoing primary PCI (show SERPINA5 Antibodies).

  2. High cardiac troponin T expression is associated with heart diseases.

  3. The results presented here have detected important prognostic differences between patients with 1 of the TNNT2 mutations (Arg92Gln) and those with the 5 other TNNT2 mutations. Carriers of the Arg92Gln mutation developed hypertrophic or dilated cardiomyopathy and had a significantly worse prognosis than those with other mutations in TNNT2.

  4. No adverse clinical events or functional changes of the device were noted, even in those with increases in cTnT.

  5. TNNT2 TNNT2

  6. This review summarizes the recent proteomic data on aminoacid sequences of cTnT and cTnI in various species, as well as selected analytical characteristics of human cardiac troponin high-sensitivity assays

  7. High-sensitivity cardiac troponin T could be used as an early biomarker for the risk stratification of patients with type-A acute aortic dissection.

  8. An association between elevated troponin levels and increased mortality was found in critically ill patients.

  9. For patients older than 65 years of age, applications of age-specific troponin T level cut-offs resulted in a decrease in acute myocardial infarction in the entire cohort.

  10. Data show that high-sensitivity cardiac troponin T (hs-cTnT) was detected in 244 (87.1%) type 2 diabetes mellitus patients.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2 (show CA2 Antibodies)+-sensitivity, structure and kinetics are brought about through PKC (show PKC Antibodies) phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  2. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  3. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  4. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  5. TnT (show TNNI1 Antibodies) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (show MYH6 Antibodies) and hypertrophic cardiomyopathy in the presence of MYH7 (show MYH7 Antibodies).

  6. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

  7. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  8. Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T.

  9. Study is the first to show that the interplay between the N terminus of cTnT and the overlapping ends of contiguous Tm effectuates different states of Tm on the actin filament.

  10. We conclude that the observed clinical severity of the cTnT Delta160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca(2 (show CA2 Antibodies)+) homeostasis

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (show TNNI1 Antibodies), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (show TPM2 Antibodies)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (show TNNI1 Antibodies) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Antigen Profile

Protein Summary

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with TNNT2

  • troponin T type 2 (cardiac) (TNNT2) antibody
  • troponin T2, cardiac (Tnnt2) antibody
  • troponin T type 2 (cardiac) (Tnnt2) antibody
  • troponin T type 2 (cardiac) (tnnt2) antibody
  • troponin T2a, cardiac (tnnt2a) antibody
  • CMH2 antibody
  • CMPD2 antibody
  • CT3 antibody
  • cTnT antibody
  • Ctt antibody
  • CTTG antibody
  • LVNC6 antibody
  • RATCTTG antibody
  • RCM3 antibody
  • tnnt2 antibody
  • Tnnt3 antibody
  • Tnt antibody
  • TnTC antibody

Protein level used designations for TNNT2

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPECIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
Selected quality suppliers for anti-Cardiac Troponin T2 (TNNT2) Antibodies
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