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anti-Tumor Protein P63 (TP63) Antibodies

TP63 encodes a member of the p53 family of transcription factors. Additionally we are shipping p63 Kits (33) and p63 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TP63 21454 P11983
TP63 8626 Q9H3D4
TP63 246334 Q9JJP6
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Top anti-p63 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB Sample Type: Human epidermis Primary Antibody Dilution: 1:100Secondary Antibody: Anti-rabbit-Alexa 488 Secondary Antibody Dilution: 1:000Color/Signal Descriptions: Green: P63  Gene Name: P63 Submitted by: Charlene O'Shea and Peter Koch, University of Colorado Denver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TP63 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TP63 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate WB Suggested Anti-TP63  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: NCI-H226 cell lysate  There is BioGPS gene expression data showing that TP63 is expressed in NCIH226 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TP63 antibody detected the TP63 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-p63 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: COLO320 Cell Lysate Lane 4: A549 Cell Lysate Lane 5: SGC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 Picoband antibody,  IHC(P): Human Oesophagus Squama Cancer Tissue Anti-p63 Picoband antibody,  All lanes: Anti P63  at 0.5ug/ml WB: Recombinant Human P63 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC (p) Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody 10 mL Log in to see 4 to 5 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB TP63 Antibody (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TP63 antibody detected the TP63 protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details

TP63 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-p63 Antibodies

  1. Human Monoclonal p63 Primary Antibody for IHC (p) - ABIN93812 : Yang, Kaghad, Wang, Gillett, Fleming, Dötsch, Andrews, Caput, McKeon: p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. in Molecular cell 1998 (PubMed)
    Show all 4 references for ABIN93812

  2. Human Polyclonal p63 Primary Antibody for WB - ABIN657886 : Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. in Nature genetics 2010 (PubMed)
    Show all 2 references for ABIN657886

  3. Chicken Polyclonal p63 Primary Antibody for WB - ABIN2778223 : Fei, de Villiers: Degradation of HPV20E6 by p53: Delta Np63 alpha and mutant p53R248W protect the wild type p53 mediated caspase-degradation. in International journal of cancer. Journal international du cancer 2008 (PubMed)

  4. Human Monoclonal p63 Primary Antibody for IHC, WB - ABIN2673817 : Zhang, Wei, Dang, Xie, Zhong, Ma, Chen: Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report. in International journal of clinical and experimental pathology 2015 (PubMed)

More Antibodies against p63 Interaction Partners

Horse (Equine) Tumor Protein P63 (TP63) interaction partners

  1. p63 expression was significantly lower in the chronic laminitic hoof than in that of control horses

Mouse (Murine) Tumor Protein P63 (TP63) interaction partners

  1. In vivo inhibition of both p63 (show CKAP4 Antibodies) and p73 (show ARHGAP24 Antibodies) in combination accelerates tumor regression and increases survival of p53 (show TP53 Antibodies)-deficient mice.

  2. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Antibodies) (P2X7R (show P2RX7 Antibodies)) and plays a role in lymphoid neoplasm metastasis.

  3. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Antibodies) and actin mediated via gelsolin (show GSN Antibodies), suggesting that CCT (show FLVCR2 Antibodies) may influence processes depending on gelsolin (show GSN Antibodies) activity, such as cell motility.

  4. p63 (show CKAP4 Antibodies) expression could be detected as early as E8.5 in mouse embryos preceding epidermal commitment.

  5. Lack of embryonic brain development was found in p63 (show CKAP4 Antibodies)-knockout mice.

  6. Data show that the transcription factor protein (show SSRP1 Antibodies) 63 (p63 (show CKAP4 Antibodies)) is a master regulator of the transition from the reserve to the active stem cell pool in the epithelium.

  7. Pvrl1 (show PVRL1 Antibodies) is a bona fide target gene of the transcription factor p63 (show CKAP4 Antibodies), whereas Pvrl4 (show PVRL4 Antibodies) regulation is linked to epidermal differentiation and is under Irf6 (show IRF6 Antibodies)

  8. Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.

  9. Some miRs control p63 (show CKAP4 Antibodies) expression, and p63 (show CKAP4 Antibodies) regulates the miR (show MLXIP Antibodies) expression profile in the epidermis. p63 (show CKAP4 Antibodies) controls miR (show MLXIP Antibodies) expression at different levels.

  10. p63 (show CKAP4 Antibodies) antagonizes p53 (show TP53 Antibodies) to promote cellular survival, whereas p73 (show ARHGAP24 Antibodies) regulates self-renewal and p53 (show TP53 Antibodies)-mediated apoptosis versus senescence.

Human Tumor Protein P63 (TP63) interaction partners

  1. Suggest p63 (show RPE65 Antibodies) is a reliable marker in non-small cell lung carcinoma and can be used in differential diagnosis.

  2. demonstrated the role of OTX2 (show OTX2 Antibodies) on TAp63 regulation necessary for the correct formation of macular neuroepithelium

  3. a transcript encoding the death receptor DR5 (show TNFRSF10B Antibodies) originates from an ERV9-LTR inserted upstream of the protein coding regions of the TNFRSF10B (show TNFRSF10B Antibodies) gene, and it shows an expression pattern similar to GTAp63

  4. We report a multiplex nonconsanguineous family with TP63 nonsense mutation leading to a premature termination codon (PTC (show F9 Antibodies)) (p.Gln16X), but the same mutation gave rise to marked phenotypic variability

  5. UPII, GATA3, and p40, when used in combination, are highly sensitive in the differential diagnosis of invasive urothelial carcinoma.

  6. T allele reduced the post-transcriptional levels of TP63 mediated by interfering binding efficiency of miR (show MLXIP Antibodies)-140-5p. In addition, overexpression of miR (show MLXIP Antibodies)-140-5p inhibited bladder cancer cell proliferation and attenuated cell migration

  7. p63 (show RPE65 Antibodies) is a sensitive marker in the diagnosis of mucoepidermoid carcinoma

  8. DeltaNp63-CYGB (show CYGB Antibodies) axis is also present in lung and breast cancer cell lines, indicating that CYGB (show CYGB Antibodies)-mediated ROS (show ROS1 Antibodies)-scavenging activity may also have a role in epithelial tumours

  9. human breast tumors data sets the MTSS1 (show MTSS1 Antibodies)/p63 (show RPE65 Antibodies) co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1 (show MTSS1 Antibodies)/p63 (show RPE65 Antibodies) axis might be functionally important to regulate breast tumor progression

  10. deltaNp63 has an antimetastatic role in the context of p53 (show TP53 Antibodies) deficiency and epidermis

Zebrafish Tumor Protein P63 (TP63) interaction partners

  1. they unravel essential roles of TAp63 and p53 (show TP53 Antibodies) to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch (show NOTCH1 Antibodies) signalling and caspase 3 (show CASP3 Antibodies) activity.

  2. the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma (show BBC3 Antibodies) transcription in response to ER stress.

  3. Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63)

  4. DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63)

  5. rps19 (show RPS19 Antibodies)-deficient phenotype is mediated by dysregulation of deltaNp63 and p53 (show TP53 Antibodies) and results in hematopoietic and developmental abnormalities resembling Diamond-Blackfan anemia

Xenopus laevis Tumor Protein P63 (TP63) interaction partners

  1. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  2. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4 (show BMP4 Antibodies).

  3. The role of p63 as a negative Wnt (show WNT2 Antibodies)-regulator thus matches with the frequently observed downregulation of p63 during tumor progression, when cancer cells adopt a more mesenchymal, invasive phenotype.

p63 (TP63) Antigen Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with TP63

  • tumor protein p63 (TP63) antibody
  • tumor protein p63 (tp63) antibody
  • tumor protein p63 (LOC100227936) antibody
  • tumor protein p73-like (LOC100393670) antibody
  • tumor protein p73-like (LOC100433100) antibody
  • tumor protein p73-like (LOC100480840) antibody
  • tumor protein p73-like (LOC100496308) antibody
  • tumor protein p73-like (LOC100512967) antibody
  • tumor protein p73-like (LOC100545037) antibody
  • tumor protein p73-like (LOC100577122) antibody
  • tumor protein p73-like (LOC100594205) antibody
  • tumor protein p73-like (LOC100611345) antibody
  • tumor protein p73-like (LOC100624851) antibody
  • tumor protein p73-like (LOC100648488) antibody
  • t-complex protein 1 (Tcp1) antibody
  • transformation related protein 63 (Trp63) antibody
  • tumor protein p63 (Tp63) antibody
  • tumor protein p63-like (LOC100355881) antibody
  • AI462811 antibody
  • AI528772 antibody
  • AIS antibody
  • B(p51A) antibody
  • B(p51B) antibody
  • c-cpn antibody
  • CCT antibody
  • Cct1 antibody
  • Ccta antibody
  • DNp63 antibody
  • EEC3 antibody
  • id:ibd3516 antibody
  • ket antibody
  • LMS antibody
  • NBP antibody
  • np63 antibody
  • OFC8 antibody
  • p40 antibody
  • p51 antibody
  • P51/P63 antibody
  • p53CP antibody
  • P63 antibody
  • p73H antibody
  • p73L antibody
  • RHS antibody
  • SHFM4 antibody
  • Tcp-1 antibody
  • TP53CP antibody
  • TP53L antibody
  • Tp63 antibody
  • tp73l antibody
  • tp73l-A antibody
  • TRic antibody
  • Trp53rp1 antibody
  • TRP63 antibody
  • wu:fc89f04 antibody
  • wu:fk85h07 antibody
  • wu:fk88b02 antibody
  • Xp63 antibody

Protein level used designations for TP63

tumor protein p63 , tumor protein 63 , p63 gamma , tumor protein p73-like , tumor protein 63-like , CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , transformation-related protein 63 , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa , delta-Np63 , fc89f04

GENE ID SPECIES
100059752 Equus caballus
100170632 Oryzias latipes
703997 Macaca mulatta
100048992 Ovis aries
460930 Pan troglodytes
100227936 Taeniopygia guttata
100386953 Callithrix jacchus
100393670 Callithrix jacchus
100433100 Pongo abelii
100444448 Pongo abelii
100480840 Ailuropoda melanoleuca
100496308 Xenopus (Silurana) tropicalis
100512967 Sus scrofa
100545037 Meleagris gallopavo
100577122 Apis mellifera
100594205 Nomascus leucogenys
100606847 Nomascus leucogenys
100611345 Pan troglodytes
100624851 Sus scrofa
100648488 Bombus terrestris
21454 Mus musculus
22061 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
260407 Danio rerio
373640 Xenopus laevis
374269 Gallus gallus
100732143 Cavia porcellus
100625258 Sus scrofa
488125 Canis lupus familiaris
615335 Bos taurus
101108874 Ovis aries
100355881 Oryctolagus cuniculus
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