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UDP Glucuronosyltransferase 1 Family, Polypeptide A9 Proteins (UGT1A9)

UGT1A9 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. Additionally we are shipping UDP Glucuronosyltransferase 1 Family, Polypeptide A9 Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT1A9 54600 O60656
Mouse UGT1A9 UGT1A9 394434 Q62452
Rat UGT1A9 UGT1A9 396552  
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Top UDP Glucuronosyltransferase 1 Family, Polypeptide A9 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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UGT1A9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) Interaction Partners

Human UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) interaction partners

  1. the in vitro glucuronidation of raloxifene in humans and monkeys was examined using liver and intestinal microsomes and recombinant UGT (show SLC35A2 Proteins) enzymes (UGT1A1 (show UGT1A1 Proteins), UGT1A8 and UGT1A9).

  2. Suggest that the enzymatic properties of UGT1A9 are considerably different between humans and cynomolgus monkeys, although humUGT1A9 and monUGT1A9 were highly conserved at the amino acid level.

  3. We observed statistically significant associations between SNP and Drug-induced liver injury at both allele and genotype levels of of UGT1A9 promoter

  4. UGT1A10 (show UGT1A10 Proteins) exhibited somewhat higher BPA (show DST Proteins) glucuronidation activity than UGT1A9, but it was lower than UGT2A1 (show UGT2A1 Proteins) and UGT2B15 (show UGT2B15 Proteins). 4.

  5. in tumor liver microsomes from HCC patients, either V(max) (maximum reaction rate, R(max) for UGT1A1) or clearance rates (V(max)/K(m), Clint) of UGT1A, UGT1A1, UGT1A4, UGT1A9 and UGT2B7 were lower than those in the adjacent normal liver microsomes

  6. Significantly lower estimated glomerular filtration rate of the renal allograft in UGT1A9 c.98C carriers did not translate into decreased allograft survival.

  7. Data shows that UGT1A9*22 allele was significantly less frequent in the Uzbek population compared to the Japanese.

  8. UGT1A9 is the major isoform responsible for the glucuronidations of fraxetin in liver microsomes.

  9. In HeLa cells overexpressing UGT1A9 there was an increase in catalysis and production of luteolin glucuronides.

  10. the UGT1A9 proximal promoter was assumed to change into the non-active form from the original sequence, and this might be one of the reasons for the tissue-specific expression of UGT1A9.

UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9) Protein Profile

Protein Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.

Gene names and symbols associated with UGT1A9

  • UDP glycosyltransferase 1 family, polypeptide A9 (UGT1A9)
  • UDP glucuronosyltransferase 1 family, polypeptide A9 (UGT1A9)
  • UDP glucuronosyltransferase 1 family, polypeptide A9 (Ugt1a9)
  • DKFZP469N0814 protein
  • HLUGP4 protein
  • LUGP4 protein
  • mUGTBr/P protein
  • SHEUGT1A07 protein
  • UDPGT protein
  • UDPGT 1-9 protein
  • UGT-1I protein
  • UGT1-09 protein
  • UGT1-9 protein
  • UGT1.9 protein
  • UGT1A9 protein
  • Ugt1a10 protein
  • Ugt1a11 protein
  • Ugt1a12 protein
  • UGT1AI protein
  • UGT1I protein
  • UGTP4 protein

Protein level used designations for UGT1A9

UDP glycosyltransferase 1 family, polypeptide A9 , UDP-glucuronosyltransferase 1-9 , UDP-glucuronosyltransferase 1A9 , UDP glucuronosyltransferase 1 family, polypeptide A9 , UDP glycosyl transferase 1A9 , UDP-glucuronosyltransferase 1-I , UDP glycosyltransferase 1 family polypeptide A12 , UDP-glucuronosyltransferase 1-7 , UDP glycosyltransferase 1 family polypeptide A10 , UDP glycosyltransferase 1 family polypeptide A11 , UDP glycosyltransferase 1 family, polypeptide A10

GENE ID SPECIES
741990 Pan troglodytes
100173720 Pongo abelii
442993 Ovis aries
771048 Gallus gallus
100126703 Papio anubis
54600 Homo sapiens
394434 Mus musculus
396552 Rattus norvegicus
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