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UDP Glucuronosyltransferase 2 Family, Polypeptide B10 Proteins (UGT2B10)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.. Additionally we are shipping UGT2B10 Antibodies (29) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT2B10 7365 P36537
Rat UGT2B10 UGT2B10 305264  
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Top UGT2B10 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UGT2B10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for UDP Glucuronosyltransferase 2 Family, Polypeptide B10 (UGT2B10) Interaction Partners

Human UDP Glucuronosyltransferase 2 Family, Polypeptide B10 (UGT2B10) interaction partners

  1. Spatial features influence the potency of UGT2B10 inhibition.

  2. UGT2B10 variant allele carriers had increased levels of C-oxidation (P = 0.0099)and all pathways should be considered when characterizing the role of nicotine metabolism on smoking behavior and cancer risk.

  3. CYP2A6 (show CYP2A6 Proteins) and UGT2B10 genotype explain 53% of the variance in oral nicotine glucuronidation. They are also significantly associated with undeuterated (D0) nicotine glucuronidation in individuals smoking ad libitum.

  4. the substrate specificity of UGT2B10, highlighting its preference for tertiary amines with higher affinities and clearance values than those of UGT1A4 and UGT1A3.

  5. UGT2B17 and UGT2B10 play key roles in the glucuronidation of 3HC in the human liver and that functional polymorphisms in UGT2B17 and UGT2B10 are associated with significantly reduced glucuronidation activities against 3HC.

  6. Data show that UGT2B10 predicts MD independently of age, hormone therapy and parity.

  7. Data suggest that UGTs 2B10 and 2B17 play important roles in the glucuronidation of nicotine and suggest that the UGT2B10 codon 67 SNP and the UGT2B17 gene deletion reduce overall glucuronidation rates of nicotine and its major metabolites in smokers.

  8. UGT2B10 genotype influences nicotine metabolism and should be taken into account when characterizing the role of nicotine metabolism on smoking.

  9. Nicotine glucuronidation and UGT2B10 is reported.

  10. Data suggest that UGT2B10 is the major hepatic enzyme involved in nicotine/cotinine glucuronidation and that the UGT2B10*2 variant reduces nicotine- and cotinine-N-glucuronidation formation and plays a role in nicotine metabolism and elimination.

UGT2B10 Protein Profile

Protein Summary

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Gene names and symbols associated with UGT2B10

  • UDP glucuronosyltransferase 2 family, polypeptide B10 (UGT2B10)
  • UDP glucuronosyltransferase 2 family, polypeptide B10 (Ugt2b10)
  • UDPGT2B10 protein
  • UGT2B4 protein
  • UGT2B7 protein
  • UGT2B28 protein
  • Ugt2b34 protein

Protein level used designations for UGT2B10

UDP glycosyltransferase 2 family, polypeptide B28 , UDP glucuronosyltransferase 2B10 , UDP glucuronosyltransferase 2 family, polypeptide B4 , UDP glucuronosyltransferase 2 family, polypeptide B7 , UDP glucuronosyltransferase 2 family, polypeptide B10 , UDP-glucuronosyltransferase 2B10-like , UDP-glucuronosyltransferase 2B10 , UDPGT 2B10 , UDP glucuronosyltransferase 2 family, polypeptide B34 , UDP glycosyltransferase 2 family, polypeptide B10

GENE ID SPECIES
461287 Pan troglodytes
533587 Bos taurus
100441531 Pongo abelii
100595736 Nomascus leucogenys
7365 Homo sapiens
305264 Rattus norvegicus
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