UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6) Proteins (GALNT6)

GALNT6 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Additionally we are shipping GALNT6 Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GALNT6 207839 Q8C7U7
Rat GALNT6 GALNT6 683264  
GALNT6 11226 Q8NCL4
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top GALNT6 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$205.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details

GALNT6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human , ,
, , ,

More Proteins for UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6) Interaction Partners

Mouse (Murine) UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6) interaction partners

  1. This paper describes the identification and cloning of the orthologous human enzyme of mouse UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6.

Human UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6) interaction partners

  1. GalNAcT6 role in cancer [review]

  2. Findings show that the expression of GalNAc-T6 in endometrial carcinoma is significantly related to E-cadherin (show CDH1 Proteins) expression, and better prognosis and overall survival.

  3. Study showed that GalNAc-T6 expression in epithelial ovarian carcinoma was different according to pathological type. In low-grade serous carcinoma, GalNAc-T6 expression may contribute to improved long-term survival.

  4. GALNT6-induced O-glycosylation is critical for the stability, subcellular localization, and anti-apoptotic function of GRP78 (show HSPA5 Proteins) protein in cancer cells. We also suggest that GRP78 (show HSPA5 Proteins) might enhance the activity of GALNT6 in carcinogenesis through driving Golgi-to-ER relocation of GALNT6.

  5. knockdown of GALNT6 caused drastic morphological changes of pancreatic cells, accompanied with the cadherin switching from P-cadherin to E-cadherin (show CDH1 Proteins).

  6. Role of N-acetylgalactosaminyltransferase (show B4GALNT2 Proteins) 6 in early tumorigenesis and formation of metastasis.

  7. These data suggest that excess O-glycosylation on APP (show APP Proteins) by GalNAc-T6 inhibits Abeta (show APP Proteins) production.

  8. GALNT6-fibronectin (show FN1 Proteins) pathway should be a critical component for breast cancer development and progression.

  9. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I (show ST6GALNAC1 Proteins) expression in breast cancer is associated with better prognosis.

Xenopus laevis UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6) interaction partners

  1. These enzymes, xGalNAc-T6 and xGalNAc- T16 (show FBLN3 Proteins), from different branches of the N-acetylgalactosaminyltransferase (show B4GALNT2 Proteins) do not only display differential substrate specificities, but also specific and distinct expression pattern and biological activities in vivo.

GALNT6 Protein Profile

Protein Summary

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.

Gene names and symbols associated with GALNT6

  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (Galnt6)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (galnt6)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (Galnt6)
  • 4632410F13 protein
  • AW047994 protein
  • fc23d02 protein
  • fc56f12 protein
  • galnac-t6 protein
  • galnact6 protein
  • wu:fc23d02 protein
  • wu:fc56f12 protein
  • zgc:77836 protein

Protein level used designations for GALNT6

polypeptide N-acetylgalactosaminyltransferase 6 , UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6 , galNAc-T6 , polypeptide GalNAc transferase 6 , pp-GaNTase 6 , protein-UDP acetylgalactosaminyltransferase 6 , N-acetylgalactosaminyltransferase T-6 , Protein-UDP acetylgalactosaminyltransferase 6 , UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 , GalNAc transferase 6 , UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6

GENE ID SPECIES
607787 Canis lupus familiaris
429501 Gallus gallus
506903 Bos taurus
207839 Mus musculus
406477 Danio rerio
683264 Rattus norvegicus
11226 Homo sapiens
100381149 Xenopus laevis
100361647 Rattus norvegicus
Selected quality suppliers for GALNT6 Proteins (GALNT6)
Did you look for something else?