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Ubiquitin Specific Peptidase 12 Proteins (USP12)

Deubiquitinating enzyme. Additionally we are shipping USP12 Antibodies (72) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP12 22217 Q9D9M2
Rat USP12 USP12 360763  
USP12 219333 O75317
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Top USP12 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,010.33
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 56 to 66 Days
$3,019.50
Details

USP12 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Ubiquitin Specific Peptidase 12 (USP12) Interaction Partners

Mouse (Murine) Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. Product has deubiquitinating enzyme activity and sequence analysis showed 98.3% amino acid identity with human UBH1.

Xenopus laevis Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. we identified USP12 and USP46 as histone H2A and H2B deubiquitinases that regulate Xenopus development

Human Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. Usp12 deubiquitylates and prevents lysosomal degradation of LAT and Trat1 to maintain the proximal TCR complex for the duration of signaling.

  2. Results suggest role for USP46 (show USP46 Proteins)/USP12 in Epstein-Barr virus induced growth transformation.

  3. Usp12 directly deubiquitinates and stabilises the Akt (show AKT1 Proteins) phosphatases PHLPP and PHLPPL (show PHLPP2 Proteins) resulting in decreased levels of active pAkt (show AKT1 Proteins).

  4. Coimmunoprecipitation experiments indicated that human papillomavirus type 31 E1 assembles into a ternary complex with UAF1 (show WDR48 Proteins) and any one of these three USPs: USP1 (show USP1 Proteins), USP12 and USP46 (show USP46 Proteins).

  5. our results reveal WDR48 and USP12 as novel PHLPP1 regulators and potential suppressors of tumor cell survival

  6. Usp12 acts in a pro-proliferative manner by stabilizing AR and enhancing its cellular function.

  7. The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch (show NOTCH1 Proteins) signaling acting on notch (show NOTCH1 Proteins) receptor trafficking toward degradation.

  8. WDR20 (show WDR20 Proteins) serves as a stimulatory subunit for preserving and regulating the activity of the subset of the UAF1 (show WDR48 Proteins) x USP12 complexes

  9. two novel multisubunit deubiquitinating enzyme complexes containing USP12 and USP46 (show USP46 Proteins), respectively. Both complexes contain the UAF1 (show WDR48 Proteins) protein as a bona fide subunit. Interestingly, UAF1 (show WDR48 Proteins)

USP12 Protein Profile

Protein Summary

Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity).

Gene names and symbols associated with USP12

  • ubiquitin specific peptidase 12 (usp12)
  • ubiquitin specific peptidase 12 (USP12)
  • Ubiquitin carboxyl-terminal hydrolase 12 (ubp12)
  • ubiquitin specific peptidase 12 (Usp12)
  • ubiquitin specific peptidase 12 (usp12-a)
  • ubiquitin specific peptidase 12 pseudogene 1 (USP12P1)
  • ubiquitin specific peptidase 12a (usp12a)
  • hapln3 protein
  • sb:eu882 protein
  • UBH1 protein
  • USP12 protein
  • USP12L1 protein
  • USP12P1 protein
  • wu:fi09d12 protein

Protein level used designations for USP12

ubiquitin thiolesterase 12 , hyaluronan and proteoglycan link protein 3 , ubiquitin specific peptidase 12 , ubiquitin specific peptidase 12 pseudogene 1 , Deubiquitinating enzyme 12 , Ubiquitin thioesterase 12 , Ubiquitin-specific-processing protease 12 , ubiquitin carboxyl-terminal hydrolase 12 , deubiquitinating enzyme 12 , ubiquitin hydrolyzing enzyme 1 , ubiquitin specific protease 12 , ubiquitin thioesterase 12 , ubiquitin-hydrolyzing enzyme 1 , ubiquitin-specific-processing protease 12 , Deubiquitinating enzyme 12-A , Ubiquitin thioesterase 12-A , Ubiquitin-specific-processing protease 12-A , ubiquitin carboxyl-terminal hydrolase 12-A , ubiquitin thiolesterase 12-A , ubiquitin-specific protease 12-like 1 , ubiquitin specific protease 12 like 1 , deubiquitinating enzyme 12A , ubiquitin carboxyl-terminal hydrolase 12A , ubiquitin thioesterase 12A , ubiquitin thiolesterase 12A , ubiquitin-specific-processing protease 12A

GENE ID SPECIES
548802 Xenopus (Silurana) tropicalis
735835 Pan troglodytes
100511469 Sus scrofa
100194904 Salmo salar
22217 Mus musculus
734447 Xenopus laevis
428078 Gallus gallus
486033 Canis lupus familiaris
525655 Bos taurus
360763 Rattus norvegicus
219333 Homo sapiens
9959 Homo sapiens
565736 Danio rerio
Selected quality suppliers for USP12 Proteins (USP12)
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