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anti-Ubiquitin-Conjugating Enzyme E2M (ube2m) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2M Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ube2m 9040 P61081
ube2m 22192 P61082
ube2m 361509  
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Top anti-Ubiquitin-Conjugating Enzyme E2M Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-UBE2M Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate Sample Type:2. mouse brain extracts (80ug) Primary Antibody Dilution: 2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: 1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical Science 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to UBE2M on HeLa cell (antibody concentration 10 µg/mL). UBE2M monoclonal antibody (M01), clone 3C4 Western Blot analysis of UBE2M expression in Jurkat. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using UBE2M, antibody at 1:100 dilution. WB Image Sample(30 ug whole cell lysate) A:293T 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to UBE2M on HeLa cell. [antibody concentration 10 ug/ml] UBE2M monoclonal antibody (M01), clone 3C4 Western Blot analysis of UBE2M expression in Jurkat . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Chimpanzee Rabbit Un-conjugated IF, IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ube2m Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Ubiquitin-Conjugating Enzyme E2M Antibodies

  1. Human Monoclonal ube2m Primary Antibody for IF, WB - ABIN393685 : Huang, Ayrault, Hunt, Taherbhoy, Duda, Scott, Borg, Neale, Murray, Roussel, Schulman: E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. in Molecular cell 2009 (PubMed)
    Show all 5 references for ABIN393685

  2. Cow (Bovine) Polyclonal ube2m Primary Antibody for IHC, WB - ABIN2775686 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)

  3. Human Monoclonal ube2m Primary Antibody for IF, ELISA - ABIN563918 : Miller, Lau, Grouios, Mollica, Barrios-Rodiles, Liu, Datti, Morris, Wrana, Attisano: Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway. in Molecular systems biology 2009 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2M Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2M (ube2m) interaction partners

  1. Polymorphisms in the UBE2M gene are associated with cetuximab efficacy in colorectal cancer.

  2. E1 (NAE1 (show NAE1 Antibodies) and UBA3 (show UBA3 Antibodies)) and E2 (UBC12) enzymes, as well as global NEDD8 (show NEDD8 Antibodies) conjugation, were upregulated in over 2/3 of human intrahepatic cholangiocarcinoma

  3. UBE2M is required to maintain genome integrity by activating multiple Cullin ligases throughout the cell cycle.

  4. Distinct preferences of UBC12 and UBE2F (show UBE2F Antibodies) peptides for inhibiting different DCNLs, including the oncogenic DCNL1 (show DCUN1D1 Antibodies).

  5. Our results demonstrate a role for UBE2M in mediating cytotoxicity of gemcitabine in human urothelial carcinoma cells.

  6. crystal structure of a complex between the C-terminal domain from NEDD8 (show NEDD8 Antibodies)'s heterodimeric E1 (APPBP1 (show NAE1 Antibodies)-UBA3 (show UBA3 Antibodies)) and the catalytic core domain of NEDD8 (show NEDD8 Antibodies)'s E2 (Ubc12)

  7. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2M (ube2m) interaction partners

  1. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

Ubiquitin-Conjugating Enzyme E2M (ube2m) Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.

Gene names and symbols associated with ube2m

  • ubiquitin-conjugating enzyme E2M (ube2m) antibody
  • ubiquitin-conjugating enzyme E2M (LOC692934) antibody
  • ubiquitin-conjugating enzyme E2M (UBE2M) antibody
  • ubiquitin-conjugating enzyme E2M (LOC100341057) antibody
  • NEDD8-conjugating enzyme (ube2m) antibody
  • ubiquitin-conjugating enzyme E2M (Ube2m) antibody
  • 2510040H03Rik antibody
  • DDBDRAFT_0204633 antibody
  • DDBDRAFT_0238042 antibody
  • DDB_0204633 antibody
  • DDB_0238042 antibody
  • hUbc12 antibody
  • Ubc-rs2 antibody
  • UBC12 antibody

Protein level used designations for ube2m

NEDD8 carrier protein , NEDD8 protein ligase , NEDD8-conjugating enzyme Ubc12 , ubiquitin-conjugating enzyme E2M (UBC12 homolog) , ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) , ubiquitin-conjugating enzyme E2M , ubiquitin-conjugating enzyme E2 M , ubiquitin carrier protein M , ubiquitin-protein ligase M , yeast UBC12 homolog , UBC12 homolog, yeast , ubiquitin C, related sequence 2

GENE ID SPECIES
394553 Xenopus (Silurana) tropicalis
692934 Bombyx mori
742993 Pan troglodytes
100341057 Oryctolagus cuniculus
8623215 Dictyostelium discoideum AX4
9040 Homo sapiens
22192 Mus musculus
361509 Rattus norvegicus
446800 Xenopus laevis
484221 Canis lupus familiaris
613343 Bos taurus
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