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anti-Unc-119 Homolog (C. Elegans) (UNC119) Antibodies

UNC119 is specifically expressed in the photoreceptors in the retina. Additionally we are shipping UNC119 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UNC119 58830  
UNC119 9094 Q13432
UNC119 22248 Q9Z2R6
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Top anti-UNC119 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UNC119 Antibody (Center) (ABIN653320) in mouse testis tissue lysates (35 µg/lane). UNC119 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with RS18 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human testis tissue reacted with RS18 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of UNC119 Antibody (Center) in mouse testis tissue lysates (35 µg/lane). UNC119 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of UNC119 expression in transfected 293T cell line by UNC119 monoclonal antibody (M01), clone 2F9-2A9. Lane 1: UNC119 transfected lysate(27 KDa). Lane 2: Non-transfected lysate. 0.05 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of UNC119 transfected lysate using anti-UNC119 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with UNC119 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of UNC119 expression in transfected 293T cell line by UNC119 MaxPab polyclonal antibody.Lane 1: UNC119 transfected lysate(27.00 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of UNC119 expression in transfected 293T cell line by UNC119 monoclonal antibody (M01A), clone 2F9-2A9.Lane 1: UNC119 transfected lysate(27 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (52.14 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB   400 μL Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated IP, ELISA, WB Western Blot analysis of UNC119 expression in transfected 293T cell line by UNC119 monoclonal antibody (M01), clone 2F9-2A9.Lane 1: UNC119 transfected lysate(27 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (52.14 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, IP, WB Western Blot analysis of UNC119 expression in transfected 293T cell line by UNC119 MaxPab polyclonal antibody.Lane 1: UNC119 transfected lysate(26.4 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to UNC119 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

UNC119 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) ,


Human ,
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Mouse (Murine) ,


Top referenced anti-UNC119 Antibodies

  1. Human Polyclonal UNC119 Primary Antibody for EIA, IHC (p) - ABIN955450 : Karim, Vepachedu, Gorska, Alam: UNC119 inhibits dynamin and dynamin-dependent endocytic processes. in Cellular signalling 2009 (PubMed)
    Show all 3 references for ABIN955450

  2. Human Polyclonal UNC119 Primary Antibody for IHC (p), WB - ABIN653320 : Vepachedu, Gorska, Singhania, Cosgrove, Brown, Alam: Unc119 regulates myofibroblast differentiation through the activation of Fyn and the p38 MAPK pathway. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

More Antibodies against UNC119 Interaction Partners

Human Unc-119 Homolog (C. Elegans) (UNC119) interaction partners

  1. UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis.

  2. The profile of UNC119a subcellular distribution remained largely unchanged under all tested conditions of illumination, and correlated with the profile of Galpha(t1 (show GNAT1 Antibodies)) following its light-dependent translocation.

  3. The discovery of the UNC119 defect provides a molecular mechanism for a subset of patients with this previously unexplained disease. Here we review our recent findings on the UNC119 mutation in ICL.

  4. Crystal structures of Arl3 in complex with UNC119a reveal the molecular basis of specificity. The N-terminal amphipathic helix of Arl3.GppNHp is not displaced by the interswitch toggle but remains bound on the surface of the protein

  5. Interaction of transducin (show GNAT1 Antibodies) with uncoordinated 119 protein (UNC119): implications for the model of transducin (show GNAT1 Antibodies) trafficking in rod photoreceptors.

  6. This study demonistrated that UNC119 is a Galpha subunit cofactor essential for G protein trafficking in sensory cilia.

  7. Heightened expression of Unc119 promotes T helper type (Th)2 cells, inhibits Th1 cell differentiation, and contributes to the pathogenesis of asthma in humans.

  8. identification as activator of SRC (show SRC Antibodies)-type tyrosine kinases

  9. The presence of ARL2 (show ARL2 Antibodies) in the retina and co-localization with HRG4 was confirmed. Amino acid residues of PDEdelta involved in binding ARL2 (show ARL2 Antibodies) and forming a hydrophobic pocket were shown to be highly conserved in HRG4

  10. Unc119 plays an important role in fibrotic processes through myofibroblast differentiation; Unc119 increases the kinase activity of Fyn (show FYN Antibodies) and associates with it in coprecipitation and colocalization studies.

Cow (Bovine) Unc-119 Homolog (C. Elegans) (UNC119) interaction partners

  1. Interaction of transducin (show GNAT1 Antibodies) with uncoordinated 119 protein (UNC119): implications for the model of transducin (show GNAT1 Antibodies) trafficking in rod photoreceptors.

Mouse (Murine) Unc-119 Homolog (C. Elegans) (UNC119) interaction partners

  1. Knockout of Unc119 partially reversed the transport defect of GRK1 (show GRK1 Antibodies) in cone photoreceptors caused by deletion of Pde6d (show PDE6D Antibodies).

  2. Unc119 has a critical role in the development of airway inflammation, mucus production, and bronchial hyperreactivity in a mouse model of experimental asthma.

  3. Unc119 is a receptor-associated activator of Src (show SRC Antibodies)-type kinases.

  4. The results support a novel mechanism of retinal degeneration in which preapoptotic degeneration starts in the photoreceptor synapse because of a deficiency in ANT-1 (show SLC25A4 Antibodies) and spreads to the secondary neuron transsynaptically, followed by apoptosis.

  5. Unc119 plays an important role in fibrotic processes through myofibroblast differentiation; Unc119 increases the kinase activity of Fyn (show FYN Antibodies) and associates with it in coprecipitation and colocalization studies.

  6. This study provides evidence for the interaction of CaBP4 (show CABP4 Antibodies) with Unc119 at the photoreceptor synapse.

  7. Unc119 orchestrates the recruitment of the actin-based motor protein (show MYO7A Antibodies), myosin 5B, and the organization of multiprotein complexes on endosomes. The Unc119-regulated pathway is essential for immunological synapse formation and T cell activation.

UNC119 Antigen Profile

Protein Summary

This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with UNC119

  • unc-119 (unc-119) antibody
  • retinal gene 4 (rtg4) antibody
  • unc-119 homolog (C. elegans) (UNC119) antibody
  • unc-119 homolog B (unc119b) antibody
  • unc-119 homolog b (C. elegans) (unc119b) antibody
  • flagellar protein UNC119 (UNC119) antibody
  • unc-119 homolog (unc119) antibody
  • unc119 homolog (C. elegans) (Unc119h) antibody
  • unc-119 homolog 1 (unc119.1) antibody
  • unc-119 homolog (un119) antibody
  • unc-119 homolog (C. elegans) (Unc119) antibody
  • UNC-119 homolog (C. elegans) (Unc119) antibody
  • anon-EST:Posey123 antibody
  • CG1659 antibody
  • D11Bhm52 antibody
  • DmelCG1659 antibody
  • dm unc-119 antibody
  • HRG4 antibody
  • id:ibd2212 antibody
  • MRG4 antibody
  • POC7 antibody
  • POC7A antibody
  • Rg4 antibody
  • RRG4 antibody
  • Rtg4 antibody
  • unc-119 antibody
  • unc119 antibody
  • unc119.2 antibody
  • unc119b antibody
  • Unc119h antibody
  • Uncl19 antibody
  • wu:fc47b02 antibody
  • zgc:111863 antibody
  • zgc:136476 antibody

Protein level used designations for UNC119

unc-119 , CG1659-PA , unc-119-PA , retinal gene 4 , unc-119 homolog (C. elegans) , unc-119 homolog B , unc-119 homolog 2 , unc-119 homolog b , unc-119-like protein 2 , flagellar protein UNC119 , unc-119 homolog , unc119 homolog (C. elegans) , Unc119c , protein unc-119 homolog 1 , protein unc-119 homolog B , POC7 centriolar protein homolog A , protein unc-119 homolog A , retinal protein 4

GENE ID SPECIES
31664 Drosophila melanogaster
266795 Danio rerio
455028 Pan troglodytes
549569 Xenopus (Silurana) tropicalis
678653 Danio rerio
771690 Gallus gallus
9622771 Volvox carteri f. nagariensis
100127819 Xenopus (Silurana) tropicalis
58830 Rattus norvegicus
338230 Danio rerio
100380832 Salmo salar
9094 Homo sapiens
538501 Bos taurus
22248 Mus musculus
29402 Rattus norvegicus
491169 Canis lupus familiaris
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