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Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability..
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findings demonstrate the fundamental significance of UNC80 and basal ionic conductance to human health
UNC80 encodes a large protein that is necessary for the stability and function of NALCN and for bridging NALCN to UNC79 to form a functional complex
UNC80 functions as a scaffold for Src (show SRC Antibodies) kinases in NALCN (show NALCN Antibodies) channel function.
Therefore, extracellular Ca(2+) influences neuronal excitability through the unc-79 homolog modifier of locomotor activity 3-UNC80-NALCN complex in a G protein-dependent fashion
in the mouse hippocampal and ventral tegmental area neurons, substance P and neurotensin activate a channel complex containing NALCN and a large previously unknown protein UNC-80
Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
, protein unc-80 homolog
, NALCN channel associated protein