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V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Proteins (MAF)

The protein encoded by MAF is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Additionally we are shipping V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Antibodies (95) and V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAF 17132 P54843
MAF 4094 O75444
MAF 54267 P54844
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Top V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,880.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,959.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,010.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details

MAF Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) Interaction Partners

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) interaction partners

  1. MafB (show MAFB Proteins) and c-Maf have different expression patterns in macrophages, suggesting differences in function.

  2. HERC4 (show HERC4 Proteins) mediates c-Maf ubiquitination and delays growth of multiple myeloma.

  3. Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin (show CRYAA Proteins) both directly and indirectly via up-regulation of c-Maf.

  4. Tec (show NR4A3 Proteins) enhances c-Maf-dependent IL-4 (show IL4 Proteins) promoter activity. This effect of Tec (show NR4A3 Proteins) is counteracted by Ptpn22 (show PTPN22 Proteins), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf thereby attenuating its transcriptional activity.

  5. endogenous small-Maf factors negatively regulate beta-cell function by competing for MafA (show MAFA Proteins) binding, and thus, the inhibition of small-Maf activity can improve beta-cell function

  6. The melanoma microenvironment contributes to skewing of CD8 (show CD8A Proteins) T cell differentiation programs, in part by TGFbeta (show TGFB1 Proteins)/IL-6 (show IL6 Proteins)-mediated induction of Maf.

  7. Sox5 (show SOX5 Proteins) physically associates with c-Maf via the HMG (show SSRP1 Proteins) domain of Sox5 (show SOX5 Proteins) and DNA-binding domain of c-Maf, and Sox5 (show SOX5 Proteins) together with c-Maf directly activates the promoter of RORgammat in CD4 (show CD4 Proteins)(+) T cells.

  8. KLF13 (show KLF13 Proteins) directly binds to IL-4 (show IL4 Proteins) promoter regions and synergizes with c-Maf to positively regulate IL-4 (show IL4 Proteins) expression.

  9. The p53 (show TP53 Proteins) transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf.

  10. Translocations between IGH and MAF may arise only in the absence of close proximity to the more frequent partners in multiple myeloma.

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) interaction partners

  1. Findings implicate the strong effects of ROS (show ROS1 Proteins) on multiple stem cell functions with a central role for c-Maf in stem cell senescence.

  2. Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin (show CRYAA Proteins) both directly and indirectly via up-regulation of c-Maf.

  3. Data suggest miR (show MLXIP Proteins)-1290 as the new oncomiR involved in laryngeal squamous cell carcinoma pathogenesis probably through downregulation of its target genes MAF and ITPR2 (show ITPR2 Proteins).

  4. Results suggest that MAF is a mediator of breast cancer bone metastasis. 16q23 gain or MAF protein overexpression in tumors may help to select patients at risk of bone relapse.

  5. Differential effect of cataract-associated mutations in MAF on transactivation of MAF target crystalline genes.

  6. Study added a novel insight for c-MAF ubiquitination and degradation, suggesting that c-MAF stability is strictly regulated.

  7. Disease-causing mutations were demonstrated to impair proper MAF phosphorylation, ubiquitination and proteasomal degradation, perturbed gene expression in primary skin fibroblasts, and induced neurodevelopmental defects in an in vivo model.

  8. MAF has a role in mediating crosstalk between Ras-MAPK (show MAPK1 Proteins) and mTOR (show FRAP1 Proteins) signaling in NF1 (show NF1 Proteins)

  9. LPS (show IRF6 Proteins) promotes PDCD4 (show PDCD4 Proteins) degradation via a pathway involving PI3K (show PIK3CA Proteins) and mTOR (show FRAP1 Proteins), releasing Twist2 (show TWIST2 Proteins), which induces IL-10 (show IL10 Proteins) via c-Maf.

  10. All four of the genes originally identified as showing genome-wide significance (IRF6 (show IRF6 Proteins), ABCA4 (show ABCA4 Proteins) and MAF, plus the 8q24 region) were confirmed in this independent sample of trios (who were primarily of European and Southeast Asian ancestry).

V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) Protein Profile

Protein Summary

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAF

  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (MAF)
  • avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog (Maf)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog (MAF)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog (Maf)
  • v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog (maf)
  • 2810401A20Rik protein
  • A230108G15Rik protein
  • AW047063 protein
  • C-Maf protein
  • CCA4 protein
  • cMaf protein
  • DKFZp459D1731 protein
  • fl13d12 protein
  • MAF protein
  • Maf2 protein
  • wu:fl13d12 protein
  • Z-cmaf protein

Protein level used designations for MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) , V-maf musculoaponeurotic fibrosarcoma oncogene homolog , c-Maf long form , proto-oncogene c-maf , transcription factor Maf , Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene , T lymphocyte c-maf long form , c-maf proto-oncogene , proto-oncogene c-Maf , C-Maf , transcription factor Maf-2 , c-Maf , Proto-oncogene c-maf

GENE ID SPECIES
454260 Pan troglodytes
100294582 Pongo abelii
17132 Mus musculus
4094 Homo sapiens
54267 Rattus norvegicus
114467 Danio rerio
693248 Gallus gallus
782481 Bos taurus
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