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anti-Valosin Containing Protein (vcp) Antibodies

The protein encoded by vcp is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. Additionally we are shipping Valosin Containing Protein Kits (17) and Valosin Containing Protein Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
vcp 7415 P55072
vcp 269523 Q01853
vcp 116643 P46462
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Top anti-Valosin Containing Protein Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of VCP Antibody (C-term) (ABIN390907) in Jurkat, 293, MDA-MB231 cell line lysates (35 µg/lane). VCP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with VCP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of VCP Antibody (C-term) in Jurkat, 293, MDA-MB231 cell line lysates (35ug/lane). VCP (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Mouse Un-conjugated IF, WB Western blot analysis of VCP on a mouse cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-VCP antibody. Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2.2). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, WB WB Suggested Anti-VCP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver Lanes: 1. Mouse WT brain extract (841 µg) 2. Rat brain extract (841 µg) Primary Antibody Dilution: 2 µg/mLSecondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: 1: 0,000  Gene Name: VCP Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB VCP monoclonal antibody (M03), clone 4A8. Western Blot analysis of VCP expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 6 to 8 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti- VCP Picoband antibody, IHC(F) IHC(F): Rat Brain Tissue Anti- VCP Picoband antibody, IHC(P) IHC(P): Mouse Brain Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with starved 24h, using VCP (Phospho-Ser352) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-VCP antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue Anti-VCP antibody, IHC(P) IHC(P): Rat Epinephros Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

vcp Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Valosin Containing Protein Antibodies

  1. Human Monoclonal vcp Primary Antibody for WB - ABIN393752 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393752

  2. Chicken Monoclonal vcp Primary Antibody for IF, WB - ABIN968777 : Egerton, Ashe, Chen, Druker, Burgess, Samelson: VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation. in The EMBO journal 1992 (PubMed)
    Show all 4 references for ABIN968777

  3. Human Monoclonal vcp Primary Antibody for WB - ABIN125950 : Acharya, Jacobs, Peters, Watson, Farquhar, Malhotra: The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events. in Cell 1995 (PubMed)
    Show all 4 references for ABIN125950

  4. Human Monoclonal vcp Primary Antibody for WB - ABIN1944899 : Hu, Han, Song, Peng, Huang, Ren, Gu, Huang, Li, Jiang, Fu, Zhang, Gu, Dai, Mao, Gao, Rong, Ye, Zhou, Xu, Gu, Shi, Jin, Zhang, Wu, Huang, Chen, Chen, Chen: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 3 references for ABIN1944899

  5. Human Polyclonal vcp Primary Antibody for FACS, IHC (p) - ABIN390907 : Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. in Nature biotechnology 2005 (PubMed)
    Show all 2 references for ABIN390907

More Antibodies against Valosin Containing Protein Interaction Partners

Human Valosin Containing Protein (vcp) interaction partners

  1. depletion of VCP enzymatic activity triggers cancer cell death in part through inadequate regulation of protein synthesis and amino acid metabolism.

  2. new role of VCP/p97 segregase in the timely processing of ubiquitinated CSB (show ERCC6 Antibodies) from damaged chromatin.

  3. Ankrd13 proteins cooperate with VCP to regulate the lysosomal trafficking of ubiquitinated Cav-1 (show CAV1 Antibodies).

  4. results suggest that human Cdc48 interacts functionally with the 20S proteasome (show PSMA5 Antibodies).

  5. we show that loss of VCP induces endoplasmic reticulum stress and epithelial-mesenchymal transition

  6. interaction between SelK (show HSP Antibodies) and p97(VCP) is SelS (show SELS Antibodies)-dependent, and the resulting ERAD complex (SelS (show SELS Antibodies)-p97(VCP)-SelK (show HSP Antibodies)) plays an important role in ERAD and ER stress

  7. this study demonstrates significant correlation between the cytoplasmic expression of VCP and adverse prognosis in breast carcinoma, suggesting that VCP may serve as a prognostic biomarker in breast carcinoma.

  8. UBXD1 (show UBXN6 Antibodies)-N intercalates into the p97 (show EIF4G2 Antibodies)-ND1 (show MT-ND1 Antibodies) interface, thereby modulating interdomain communication of p97 (show EIF4G2 Antibodies) domains and its activity with relevance for disease pathogenesis

  9. Our results provide the first structural clues of how VCP mutations may influence the activity and function of the D2 ATPase (show DNAH8 Antibodies) ring.

  10. Data indicate that ATPase (show DNAH8 Antibodies) p97 (show EIF4G2 Antibodies) is a key mediator of several protein homeostasis processes and is a strong potential cancer target.

Mouse (Murine) Valosin Containing Protein (vcp) interaction partners

  1. VCP (valosin-containing protein), together with its cofactor P47 (show MFGE8 Antibodies) and the endoplasmic reticulum (ER) morphology regulator ATL1 (Atlastin-1 (show ATL1 Antibodies)), regulates tubular ER formation

  2. Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice

  3. Global expression profiling of VCP(R155H/+) mice identified key dysregulated signaling pathways including genes involved in the physiological system development and function, diseases and disorders, and molecular and cellular functions.

  4. The results reveal an unexpected, crucial role of ATP consumption by VCP in determining cell fate in retinitis pigmentosa, and point to a promising new neuroprotective strategy for this currently incurable disease.

  5. Pro(178) and Pro(183) of SelS (show SELS Antibodies) play important roles in the translocation of p97(VCP) to the ER membrane and protect cells from ER stress

  6. Knockdown or chemical inhibition of p97 (show EIF4G2 Antibodies) causes robust accumulation of USP33 (show USP33 Antibodies) due to inhibition of its degradation

  7. conclude that the Akt (show AKT1 Antibodies) substrate, VCP, mediates the increased expression of iNOS (show NOS2 Antibodies) downstream from Hsp22 (show HSPB8 Antibodies) through an NF-kappaB (show NFKB1 Antibodies)-dependent mechanism

  8. Molecular dynamics simulations are used to probe energetic requirements of substrate protein translocation through the p97 (show EIF4G2 Antibodies) pore and mechanisms of substrate binding and release from p97 (show EIF4G2 Antibodies) subunits during the allosteric cycle.

  9. Data indicate that genetic ablation or chemical inhibition of p97 does not diminish DRiP antigen presentation nor does it alter the levels of MHC class I molecules on the cell surface.

  10. Cav-1 (show CAV1 Antibodies) may be a cofactor in the interaction of Derlin-1 (show DERL1 Antibodies) and N-glycosylated COX-2 (show COX2 Antibodies) and may facilitate Derlin-1 (show DERL1 Antibodies)- and p97 (show EIF4G2 Antibodies) complex-mediated COX-2 (show COX2 Antibodies) ubiquitination, retrotranslocation, and degradation.

Xenopus laevis Valosin Containing Protein (vcp) interaction partners

  1. p97 is an essential regulator of DNA damage-dependent CDT1 (show CDT1 Antibodies) destruction

  2. CDC-48/p97 coordinates CDT-1 (show CDT1 Antibodies) degradation with GINS chromatin dissociation to ensure faithful DNA replication

  3. data reveal an essential pathway that regulates reformation of the nucleus after mitosis and defines ubiquitin-dependent protein extraction as a common mechanism of Cdc48/p97 activity also during nucleus formation

Cow (Bovine) Valosin Containing Protein (vcp) interaction partners

  1. results suggest that VCP plays a mechanistic role in releasing WRNp from the nucleolus

Zebrafish Valosin Containing Protein (vcp) interaction partners

  1. When we introduced CDC48 antisense morpholino oligonucleotides into zebrafish embryos, the morphant embryos were lethal and showed defects in neuronal outgrowth and neurodegeneration.

  2. CDC48 may promote cell cycling and cell proliferation via C-terminal tyrosine phosphorylation during cold acclimation in fish cells

Valosin Containing Protein (vcp) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

Gene names and symbols associated with vcp

  • valosin containing protein (VCP) antibody
  • valosin containing protein (Bm1_56585) antibody
  • valosin containing protein (LOC100136246) antibody
  • valosin containing protein (Vcp) antibody
  • valosin containing protein (vcp) antibody
  • valosin-containing protein (Vcp) antibody
  • 3110001E05 antibody
  • ALS14 antibody
  • CDC48 antibody
  • IBMPFD antibody
  • p93 antibody
  • p97 antibody
  • p97/VCP antibody
  • TERA antibody
  • wu:fd16d05 antibody
  • wu:fj63d11 antibody

Protein level used designations for vcp

transitional endoplasmic reticulum ATPase , valosin-containing protein , valosin containing protein , 15S Mg(2+)-ATPase p97 subunit , TER ATPase , yeast Cdc48p homolog , AAA ATPase p97 , Inv protein , homolog of yeast cdc48 , p97 ATPase

GENE ID SPECIES
427410 Gallus gallus
6106199 Brugia malayi
100136246 Oncorhynchus mykiss
7415 Homo sapiens
269523 Mus musculus
380491 Xenopus laevis
397524 Sus scrofa
481590 Canis lupus familiaris
507345 Bos taurus
327197 Danio rerio
116643 Rattus norvegicus
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