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anti-Voltage-Dependent Anion Channel 1 (VDAC1) Antibodies

VDAC1 encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. Additionally we are shipping VDAC1 Kits (7) and VDAC1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VDAC1 7416 P21796
VDAC1 83529 Q9Z2L0
VDAC1 22333 Q60932
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Top anti-VDAC1 Antibodies at antibodies-online.com

Showing 10 out of 143 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Western blot analysis of VDAC/Porinwith 3T3 cell lysate. 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of VDAC1 Antibody (Center) (ABIN390564) in HL-60, Y79 cell line lysates (35 µg/lane). VDAC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VDAC1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of VDAC1 Antibody (N-term) (ABIN390563) in A375 cell line and mouse heart tissue lysates (35 µg/lane). VDAC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VDAC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-VDAC1 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of VDAC1 Antibody (N-term) in A375 cell line and mouse heart tissue lysates (35ug/lane). VDAC1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot of Rabbit Anti-VDAC/Porin Antibody. Lane 1: rat heart whole cell lysate. Lane 2: none. Load: 35 µg per lane. Primary antibody: VDAC/Porin antibody at 1:1,200 for overnight at 4°C. Secondary antibody: IRDye800™ rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: ~32 kDa corresponding to VDAC/Porin (arrowhead). Other band(s): none. 25 μL Log in to see 2 to 3 Days
$139.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti VDAC Polyclonal Antibody, Unconjugated (ABIN686872) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-VDAC Picoband antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue Anti-VDAC Picoband antibody, IHC(P) IHC(P): Mouse Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Arabidopsis thaliana Rabbit Un-conjugated BN PAGE, IL, WB 50 μg Log in to see 5 to 6 Days
$375.38
Details
REACT_Bird Rabbit Un-conjugated EIA, WB 0.2 mg Log in to see 6 to 8 Days
$434.50
Details

VDAC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-VDAC1 Antibodies

  1. Arabidopsis thaliana Polyclonal VDAC1 Primary Antibody for BN PAGE, IL - ABIN3155731 : Ito, Batth, Petzold, Redding-Johanson, Mukhopadhyay, Verboom, Meyer, Millar, Heazlewood: Analysis of the Arabidopsis Cytosolic Proteome Highlights Subcellular Partitioning of Central Plant Metabolism. in Journal of proteome research 2010 (PubMed)
    Show all 10 references for ABIN3155731

  2. Bird (Avian) Polyclonal VDAC1 Primary Antibody for EIA, WB - ABIN401311 : Liu, Brouha, Grossman: Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells. in Oncogene 2004 (PubMed)
    Show all 7 references for ABIN401311

  3. Cow (Bovine) Polyclonal VDAC1 Primary Antibody for IHC, WB - ABIN2776153 : Zheng, Shi, Tian, Jiang, Jin, Chen, Almasan, Tang, Chen: Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. in Oncogene 2004 (PubMed)
    Show all 4 references for ABIN2776153

  4. Human Polyclonal VDAC1 Primary Antibody for FACS, IHC (p) - ABIN390563 : Shoshan-Barmatz, Zakar, Rosenthal, Abu-Hamad: Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase. in Biochimica et biophysica acta 2009 (PubMed)
    Show all 3 references for ABIN390563

  5. Human Polyclonal VDAC1 Primary Antibody for EIA, WB - ABIN453456 : Hiller, Garces, Malia, Orekhov, Colombini, Wagner: Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. in Science (New York, N.Y.) 2008 (PubMed)
    Show all 2 references for ABIN453456

  6. Cow (Bovine) Polyclonal VDAC1 Primary Antibody for IHC, WB - ABIN223288 : Bortner, Scoltock, Sifre, Cidlowski: Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes. in The Journal of biological chemistry 2012 (PubMed)
    Show all 2 references for ABIN223288

  7. Human Polyclonal VDAC1 Primary Antibody for IF (p), IHC (p) - ABIN686872 : Manczak, Reddy: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease. in Human molecular genetics 2012 (PubMed)

  8. Human Polyclonal VDAC1 Primary Antibody for ELISA, WB - ABIN1043886 : Bourekas, Slivka, Shah, Sunshine, Suarez: Intraarterial thrombolytic therapy within 3 hours of the onset of stroke. in Neurosurgery 2003 (PubMed)

More Antibodies against VDAC1 Interaction Partners

Arabidopsis thaliana Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. Abnormal ovules in the process of female gametogenesis were observed. Both mitochondrial transmembrane potential and ATP synthesis rate were obviously reduced in the mitochondria isolated from atvdac1 plants.

  2. Data indicate that both voltage-dependent anion channel 1 (AtVDAC1) and calcium sensor CBL1 regulate cold stress responses during seed germination and plant development.

  3. AtVDAC1 has a main function in mitochondria

  4. VDAC1 is not only necessary for normal growth but also important for disease resistance through regulation of hydrogen peroxide generation.

Human Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. Studies using B16F10 and A375 cells genetically modified for ATF2 (show ATF2 Antibodies) indicated that mitochondrial ATF2 (show ATF2 Antibodies) was able to dissociate Bim (show BCL2L11 Antibodies) from the Mcl-1 (show MCL1 Antibodies)/Bim (show BCL2L11 Antibodies) complex to trigger VDAC1 oligomerization.

  2. findings also suggest that VDAC1 may be a novel biomarker for gastric cancer

  3. serum starvation induces CREB1 (show CREB1 Antibodies) expression, in turn activating miR (show MLXIP Antibodies)-320a expression, which then down-regulates VDAC1 expression to facilitate mitophagy

  4. Reducing VDAC1 expression induces a non-apoptotic role for pro-apoptotic proteins in glioblastoma multiforme cancer cell differentiation.

  5. The works available on VDAC cysteines support the notion that VDAC1, VDAC2 (show VDAC2 Antibodies), and VDAC3 (show VDAC3 Antibodies) proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)

  6. The protective effect of miR-7 (show LILRB1 Antibodies) is partly exerted through promoting mitochondrial function by targeting VDAC1 expression.

  7. Data show that voltage-dependent anion channel 1 (VDAC1) knockout cells are resistant to AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) and mechanistic target of rapamycin (mTOR (show FRAP1 Antibodies)) modulation by itraconazole, indicating VDAC1 is the mediator of the activity.

  8. Amyloid beta -mediated toxicity involves mitochondrial and plasma membrane VDAC1, leading to mitochondrial dysfunction and apoptosis induction.

  9. PGC-1alpha (show PPARGC1A Antibodies) deficiency exacerbates high glucose-induced apoptosis in human umbilical vein endothelial cells through activation of VADC1.

  10. The serum lever of Alzheimer's disease were increase and the expression of VDAC1 strongly correlated with the Mini-Mental State Examination scores of the AD patients.

Pig (Porcine) Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. Data confirm the synthesis of VDAC1 and 2 subtypes in GV (germinal vesicle) and MII (meiosis II) stage porcine oocytes as well as their protein expression.

Cow (Bovine) Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. Results describe the expression of voltage-dependent anion channel isoforms in rat, bovine, and chicken brain mitochondria, and suggest that the nature of hexokinase binding site is not determined by the expression of a single VDAC isoform.

  2. Suggest that VDAC1 participates in volume regulatory processes in spermatozoa.

Mouse (Murine) Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. VDAC1-interacting anion transport inhibitors inhibited apoptosis via direct interaction with VDAC1 to inhibit its oligomerization and subsequent Cyto c release and apoptosis.

  2. Reducing VDAC1 expression induces a non-apoptotic role for pro-apoptotic proteins in glioblastoma multiforme cancer cell differentiation.

  3. TSPO (show TSPO Antibodies) as a novel element in the regulation of mitochondrial quality control by autophagy, and demonstrate the importance for cell homeostasis of its expression ratio with voltage-dependent anion channel 1

  4. ATP flows through VDAC through multiple pathways, in agreement with our structural data and experimentally determined physiological rates.

  5. Reduced VDAC1 expression protects against Alzheimer's disease and synaptic deficiencies.

  6. Data suggest presence of unstructured C-terminal tubulin (show TUBB Antibodies) tail in VDAC pore decreases conductance and switches selectivity from anionic to cationic rendering ATP transport virtually impossible; involves stable salt bridge (K336-tubulin (show TUBB Antibodies)/D186-Vdac1).

  7. MAVS (show MAVS Antibodies) binds to voltage-dependent anion channel 1 (VDAC1) and induces apoptosis by caspase-3 (show CASP3 Antibodies) activation, which is independent of its role in innate immunity.

  8. Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.

  9. Flexibility of the N-terminal mVDAC1 segment controls the channel's gating behavior.

  10. the N-terminal alpha-helix is located inside the pore of VDAC in the open state and remains associated with beta-strand 11 of the pore wall during voltage gating

Zebrafish Voltage-Dependent Anion Channel 1 (VDAC1) interaction partners

  1. we found that Bcl-wav controls intracellular Ca(2+) trafficking by acting on the mitochondrial voltage-dependent anion channel, and possibly on MCU, with direct consequences on actin microfilament dynamics and blastomere migration guidance.

VDAC1 Antigen Profile

Protein Summary

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

Gene names and symbols associated with VDAC1

  • voltage-dependent anion channel 1 (vdac1) antibody
  • voltage-dependent anion channel 1 (VDAC1) antibody
  • voltage dependent anion channel 1 (VDAC1) antibody
  • voltage-dependent anion channel 1 (Vdac1) antibody
  • 5076 antibody
  • AL033343 antibody
  • ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antibody
  • ATVDAC1 antibody
  • fa13f11 antibody
  • PORIN antibody
  • T22N4.9 antibody
  • T22N4_9 antibody
  • VDAC-1 antibody
  • VDAC1 antibody
  • Vdac5 antibody
  • voltage dependent anion channel 1 antibody
  • wu:fa13f11 antibody
  • zgc:85830 antibody

Protein level used designations for VDAC1

voltage-dependent anion channel 1 , outer mitochondrial membrane protein porin 1 , plasmalemmal porin , porin 31HL , porin 31HM , voltage-dependent anion-selective channel protein 1 , VDAC-1 , rVDAC1 , BR1-VDAC , brain-derived voltage-dependent anion channel 1 , VDAC-5 , mVDAC1 , mVDAC5 , voltage-dependent anion-selective channel protein 5

GENE ID SPECIES
380376 Xenopus laevis
549246 Xenopus (Silurana) tropicalis
745717 Pan troglodytes
820914 Arabidopsis thaliana
7416 Homo sapiens
83529 Rattus norvegicus
397010 Sus scrofa
282119 Bos taurus
100008751 Oryctolagus cuniculus
22333 Mus musculus
334582 Danio rerio
474681 Canis lupus familiaris
100145866 Ovis aries
100723897 Cavia porcellus
416320 Gallus gallus
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