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The protein encoded by ZMYND8 is a receptor for activated C-kinase (RACK) protein. Additionally we are shipping and many more products for this protein.
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KDM5A (show KDM5A Antibodies) demethylates H3K4 to allow ZMYND8-NuRD to operate within damaged chromatin to repair DNA double strand breaks.
ZMYND8's PHD (show PDC Antibodies)-Bromo cassette couples H3K4me1-H3K14ac with downregulation of metastasis-linked genes in prostate tumor cells.
a dual histone reader ZMYND8 (zinc finger MYND (Myeloid, Nervy and DEAF-1 (show DEAF1 Antibodies))-type containing 8), was identified to be a novel target of all trans retinoic acid.
Data suggest that epithelial-mesenchymal transition (EMT (show ITK Antibodies)) is regulated by ZMYND8 (receptor for activated protein kinase C (show GNB2L1 Antibodies)) which selectively activates gene promoters of CLDN1 (claudin 1 (show CLDN1 Antibodies)) and CDH1 (E-cadherin (show CDH1 Antibodies)) in breast cancer cells; thus, the presence of ZMYND8 could be implicated in maintaining epithelial phenotype of cells; ZMYND8 regulates invasion/migration of breast cancer cells.
Findings reveal a RACK7/KDM5C (show KDM5C Antibodies)-regulated, dynamic interchange between histone H3K4me1 and H3K4me3 at active enhancers, representing an additional layer of regulation of enhancer activity. Authors propose that RACK7/KDM5C (show KDM5C Antibodies) functions as an enhancer "brake" to ensure appropriate enhancer activity, which, when compromised, could contribute to tumorigenesis.
study identifies that ZMYND8 has CHD4 (show CHD4 Antibodies)-independent functions in regulating gene expression through its modified histone-binding ability.
identified ZMYND8 (zinc finger and MYND [myeloid, Nervy, and DEAF-1 (show DEAF1 Antibodies)] domain containing 8) as a novel DDR (show DDR1 Antibodies) factor that recruits the nucleosome remodeling and histone deacetylation (NuRD) complex to damaged chromatin
ZMYND8 induces vegfa (show VEGFA Antibodies) mRNA expression selectively in prostate cancer xenografts.
These data reveal a RCOR2 (show Rcor2 Antibodies)/ZMYND8 complex which might be involved in the regulation of neural differentiation.
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
CTCL tumor antigen se14-3
, cutaneous T-cell lymphoma-associated antigen se14-3
, predicted protein of HQ2893
, protein kinase C-binding protein 1
, zinc finger MYND domain-containing protein 8
, protein kinase C binding protein 1
, zinc finger and MYND domain containing protein 8
, spikar delta C