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The protein encoded by ZNF335 enhances transcriptional activation by ligand-bound nuclear hormone receptors. Additionally we are shipping ZNF335 Antibodies (20) and and many more products for this protein.
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we performed a meta-analysis of our data with the previous reports, identifying two further loci harbouring the ZNF335 and NIFA (show INA ELISA Kits) genes which now exceed genome-wide significance, taking the total number of CD susceptibility loci to 42.
NIF-1 expression is associated with tumor grade in bladder cancer.
Study identifies and characterizes a nuclear zinc finger protein, ZNF335/NIF-1, as a causative gene for severe microcephaly, small somatic size, and neonatal death.
CCR4 (show CCR4 ELISA Kits) plays a role in the regulation of certain endogenous RARalpha (show RARA ELISA Kits) target genes and RCD1 (show RQCD1 ELISA Kits) and CCR4 (show CCR4 ELISA Kits) might mediate their function through their interaction with NIF-1
NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor (show NR0B1 ELISA Kits) coactivator NRC (show NCOA6 ELISA Kits)
p35 (show CDK5R1 ELISA Kits) interacts with NIF-1 and regulates the subcellular localization of the protein independent of Cdk5 (show CDK5 ELISA Kits)-dependent phosphorylation. ...reveal a new mechanism of p35 (show CDK5R1 ELISA Kits) in transcriptional regulation that does not require the kinase activity of Cdk5 (show CDK5 ELISA Kits)
Results suggest that NIF-1 directs neuronal morphogenesis during early developmental stages through modulating activity-dependent gene transcription
Zinc finger protein Zfp335 is required for the formation of the naive T cell compartment.
Znf335 null mice are embryonically lethal, and conditional knockout leads to severely reduced cortical size.
The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure.
NRC-interacting factor 1
, zinc-finger/leucine-zipper co-transducer NIF1
, zinc-finger/leucine-zipper co-transducer NIF-1