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The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. Additionally we are shipping ZHX2 Proteins (4) and ZHX2 Kits (1) and many more products for this protein.
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Human Polyclonal ZHX2 Primary Antibody for ELISA, WB - ABIN564952
Liu, Clement, Kanwar, Avila-Casado, Chugh: ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. in The Journal of biological chemistry 2006
Show all 2 references for ABIN564952
Cow (Bovine) Polyclonal ZHX2 Primary Antibody for WB - ABIN2780956
Moore, Roaf, Knowles: The effects of Variations in the Inorganic Salts and the Reactivity of the External Medium upon the Nutrition, Growth, and Cell-division in Plants and Animals. in The Biochemical journal 2006
Dog (Canine) Polyclonal ZHX2 Primary Antibody for WB - ABIN2780179
Perincheri, Dingle, Peterson, Spear: Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene. in Proceedings of the National Academy of Sciences of the United States of America 2005
These results indicated that ZHX2 plays a critical role in the proliferation and osteo/odontogenic differentiation of SCAPs.
Data show that Zinc-fingers and homeoboxes 2 (ZHX2) represses nuclear transcription factor Y alpha (show NFYA Antibodies) (NF-Y)-mediated activation of multidrug resistance 1 (MDR1 (show TBC1D9 Antibodies)) transcription.
Data indicate that zinc-fingers and homeoboxes 2 (ZHX2) suppresses glypican 3 (GPC3 (show GPC3 Antibodies)) transcription by binding with its core promoter.
Two novel markers, rs7840785 (PINX1 (show PINX1 Antibodies)) and rs7844465 (ZHX2), are significantly associated with carotid intima-media thickness.
Expression of a constitutively active Raf (show RAF1 Antibodies) transgene enhances lymphoproliferation (show FAS Antibodies), indicating a role for the Ras-MAPK (show MAPK1 Antibodies) pathway in linker for activation of T cells (LAT (show LAT Antibodies))-mediated autoimmune hyperproliferation.
There was no significant difference in high and low percentage of HbF in GG, GA, and AA bearing individuals showing that ZHX2 gene variant has no role in ameliorating the severity of beta-thalassemia major in the South Indian population from Andhra Pradesh.
results demonstrate multiple mechanisms decreasing expression of tumor suppressor gene ZHX2 in Hodgkin lymphoma cell lines
Expression profiling of L-1236 cells following siRNA-mediated knockdown of ZHX2 showed inhibition of genes regulating differentiation and apoptosis, suggesting tumor suppressor activity of ZHX2.
ZHX2, a transcriptional repressor, may participate in globin gene regulation.
High ZHX2 is associated with metastasis in hepatocellular carcinoma.
NFAT1 (show NFAT1 Antibodies) protein activation can shift oncogenic Ras/Raf (show RAF1 Antibodies)/MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) signaling to acting as a tumor suppressor pathway.
The Zhx2 mutation resulted in a failure to suppress expression of lipoprotein lipase (show LPL Antibodies), a gene normally silenced in the adult liver.
molecular crosstalk between aberrant expression of Hox (show MSH2 Antibodies) molecule(s) and activated Raf (show RAF1 Antibodies) may have a key role in the MLL (show MLL Antibodies)-fusion-mediated-leukemogenesis
Zhx2 acts as a repressor of Gpc3 (show GPC3 Antibodies) in the adult liver.
The carboxyl terminus of Angptl4 (show ANGPTL4 Antibodies) alone is sufficient to suppress angiogenesis, possibly through inhibiting the Raf (show RAF1 Antibodies)/MEK (show MDK Antibodies)/ERK1/2 (show MAPK1/3 Antibodies) MAP kinase (show MAPK1 Antibodies) pathway in endothelial cells.
These findings revealed that oxidative stress, inflammation, Ras/Raf (show RAF1 Antibodies)/ERK1/2 (show MAPK1/3 Antibodies) pathway and apoptosis collectively played a crucial role in the chemopreventive activity of farnesol to inhibit the murine skin tumorigenesis.
evidence presented that ZHX2 & ephrin-B1 cytoplasmic domain can interact & regulate transcription; study identifies ZHX2 as novel regulator of neural progenitor cell maintenance & suggests potential nuclear mechanism of ephrin-B function in the cortex
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
zinc fingers and homeoboxes 2
, zinc finger and homeodomain protein 2
, zinc fingers and homeoboxes protein 2
, zinc fingers and homeoboxes protein 2-like
, AFP regulator 1
, alpha-fetoprotein regulator 1
, regulator of AFP
, transcription factor ZHX2
, zinc-fingers and homeoboxes 2
, alpha fetoprotein regulation 1, adult