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anti-Zona Pellucida Glycoprotein 2 (ZP2) Antibodies

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. Additionally we are shipping ZP2 Kits (6) and ZP2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZP2 22787 P20239
ZP2 7783 Q05996
ZP2 81828 O54767
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Top anti-ZP2 Antibodies at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ZP2 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ZP2 expression in HELA whole cell lysates (lane 1) and HEPG2 whole cell lysates (lane 2). ZP2 at 82KD was detected using rabbit anti- ZP2 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method ZP2 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- ZP2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated WB ZP2 antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ZP2 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of ZP2 expression in transfected 293T cell line by ZP2 MaxPab polyclonal antibody.Lane 1: ZP2 transfected lysate(80.96 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details

ZP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human ,
,
,
Rat (Rattus)


Top referenced anti-ZP2 Antibodies

  1. Cow (Bovine) Polyclonal ZP2 Primary Antibody for WB - ABIN2782230 : Furlong, Harris, Vazquez-Levin: Binding of recombinant human proacrosin/acrosin to zona pellucida (ZP) glycoproteins. I. Studies with recombinant human ZPA, ZPB, and ZPC. in Fertility and sterility 2005 (PubMed)

More Antibodies against ZP2 Interaction Partners

Zebrafish Zona Pellucida Glycoprotein 2 (ZP2) interaction partners

Mouse (Murine) Zona Pellucida Glycoprotein 2 (ZP2) interaction partners

  1. ZP2(51-149) sperm-binding domain is necessary for mouse gamete recognition and penetration through the zona pellucida.

  2. Studies indicate that eggs from mZP2-/- and mZP3-/- females lack a zona pellucida (ZP), and the mice are completely infertile due to a severely reduced number of ovulated eggs in their oviducts.

  3. Sperm arylsulfatase A (show ARSA Antibodies) binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner.

  4. Recombinant ovastacin (show ASTL Antibodies) cleaved ZP2 in native zonae pellucidae, documenting that ZP2 was a direct substrate of this metalloendoprotease.

  5. Cytoplasmic tails are necessary to prevent intracellular oligomerization while ensuring incorporation of processed ZP2 and ZP3 (show ZP3 Antibodies) into the zona pellucida.

  6. data indicate that sperm-egg recognition depends on the cleavage status of ZP2 and that binding at the surface of the zona is not sufficient to induce sperm acrosome exocytosis

  7. stoichiometric disposition of ZP1 (show ZP1 Antibodies), ZP2, and ZP3 (show ZP3 Antibodies) in the ovarian zona matrix revealed by double and triple immunolocalization studies

  8. Results indicate that ZP2 and ZP3 (show ZP3 Antibodies) traffic independently through the oocyte prior to assembly into the zona pellucida.

Human Zona Pellucida Glycoprotein 2 (ZP2) interaction partners

  1. ZP2(51-149) sperm-binding domain is necessary for human gamete recognition and penetration through the zona pellucida.

  2. Studies indicate that eggs from mice lacking an ortholog of ZP2 do not contain a zona pellucida (ZP), and the mice are completely infertile due to a severely reduced number of ovulated eggs in their oviducts.

  3. observed sequence variations in exons of ZP2 gene in women with infertility of unknown origin who exhibit abnormal zona pellucida; sperm-ovum interactions appear relatively normal in these patients [CASE REPORTS]

  4. Of all zona pellucida (ZP) proteins, recombinant human ZPA demonstrates the highest binding activity toward acrosin (show ACR Antibodies)

Cow (Bovine) Zona Pellucida Glycoprotein 2 (ZP2) interaction partners

  1. Polymorphism of Zp2 and the Zp3 (show ZP3 Antibodies) did not show any contribution to reproductive isolation between the bovine species.

ZP2 Antigen Profile

Protein Summary

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.

Gene names and symbols associated with ZP2

  • zona pellucida glycoprotein 2, tandem duplicate 1 (zp2.1) antibody
  • zona pellucida glycoprotein 2 (Zp2) antibody
  • zona pellucida glycoprotein 2 (sperm receptor) (ZP2) antibody
  • zona pellucida glycoprotein 2 (sperm receptor) (Zp2) antibody
  • fa12e07 antibody
  • wu:fa12e07 antibody
  • zgc:152728 antibody
  • Zp-2 antibody
  • zp2 antibody
  • ZPA antibody

Protein level used designations for ZP2

zona pellucida glycoprotein ZP2 , zona pellucida protein A , zona pellucida sperm-binding protein 2 , zona pellucida A protein , ZP1 , zona pellucida 2 glycoprotein , 75-kDa rabbit zona pellucida protein

GENE ID SPECIES
30593 Danio rerio
22787 Mus musculus
7783 Homo sapiens
403988 Canis lupus familiaris
396846 Sus scrofa
280963 Bos taurus
100009069 Oryctolagus cuniculus
81828 Rattus norvegicus
493977 Felis catus
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