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anti-Zona Pellucida Glycoprotein 4 (ZP4) Antibodies

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. Additionally we are shipping Zona Pellucida Glycoprotein 4 Proteins (4) and Zona Pellucida Glycoprotein 4 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZP4 57829 Q12836
ZP4 282833  
ZP4    
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Top anti-Zona Pellucida Glycoprotein 4 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ZP4 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB ZP4 Antibdy (C-term) (ABIN656652) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ZP4 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ZP4 antibody detected the ZP4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using ZP4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ZP4 expression in HepG2 (A), Hela (B), NIH3T3 (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 14 Days
$201.19
Details

ZP4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Rat (Rattus)


Monkey


Top referenced anti-Zona Pellucida Glycoprotein 4 Antibodies

  1. Human Polyclonal ZP4 Primary Antibody for EIA, IHC (p) - ABIN955755 : Choudhury, Ganguly, Chakrabarti, Sharma, Gupta: DNA vaccine encoding chimeric protein encompassing epitopes of human ZP3 and ZP4: immunogenicity and characterization of antibodies. in Journal of reproductive immunology 2009 (PubMed)
    Show all 5 references for ABIN955755

  2. Human Polyclonal ZP4 Primary Antibody for IHC (p), WB - ABIN656652 : Nakano, Ikeda, Taniguchi, Yagi, Fuwa, Omi, Tokuda, Tanaka, Yoshii, Kageyama, Naruse, Matsuda, Mori, Kinoshita, Tashiro: Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for ABIN656652

  3. Human Polyclonal ZP4 Primary Antibody for WB - ABIN2783828 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against Zona Pellucida Glycoprotein 4 Interaction Partners

Human Zona Pellucida Glycoprotein 4 (ZP4) interaction partners

  1. ZO4 is highly expressed in ovarian tissue in PCOS patients with regular cycle and without hyperandrogenism; in some patients with PCOS and infertility, ZP4 mutation can be found.

  2. Human ZP4 is not sufficient to support human sperm binding to the zona pellucida in transgenic mice; other zona proteins may be needed for human gamete recognition.

  3. ZPB induces acrosomal exocytosis through a Gi independent pathway.

  4. Binding sites for recombinant zona pellucida B (ZPB) glycoprotein are located both at the N- and C-terminus of proacrosin (show ACR Antibodies)

  5. induces acrosome reactions which are protein kinase-C (show PKC Antibodies), protein tyrosine kinase (show EPHA8 Antibodies), T-type Ca2 (show CA2 Antibodies)+ channels, and extracellular Ca2 (show CA2 Antibodies)+ dependent

  6. a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (show ZP3 Antibodies) (p<0.005) and ZP4 (p<0.005) was observed in presence of the immune sera

Pig (Porcine) Zona Pellucida Glycoprotein 4 (ZP4) interaction partners

  1. Porcine zona pellucida glycoprotein ZP4 is responsible for the sperm-binding activity of the ZP3 (show ZP3 Antibodies)/ZP4 complex

Zona Pellucida Glycoprotein 4 (ZP4) Antigen Profile

Protein Summary

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.

Gene names and symbols associated with ZP4

  • zona pellucida glycoprotein 4 (zp4-a) antibody
  • zona pellucida glycoprotein 4 (zp4) antibody
  • zona pellucida glycoprotein 4 (ZP4) antibody
  • zona pellucida glycoprotein 4 (Zp4) antibody
  • lzpb-a antibody
  • MGC154827 antibody
  • MGC154888 antibody
  • TAC4 antibody
  • xlZPB antibody
  • ZBP antibody
  • ZP antibody
  • Zp-4 antibody
  • Zp-X antibody
  • ZP1 antibody
  • ZP3-ALPHA antibody
  • ZPB antibody

Protein level used designations for ZP4

zona pellucida glycoprotein 4 , vitelline envelope 37k glycoprotein xlZPB , egg envelope component ZPB , zona pellucida sperm-binding protein 4 , zona pellucida B protein , tachykinin 4 , zona pellicida protein B , zona pellucida sperm-binding protein 4-like , zona pellucida protein B , zona pellucida 4 , zona pellucida B glycoprotein , zona pellucida glycoprotein 3-alpha , zona pellucida glycoprotein ZP3-alpha , zona pellucida protein 3-alpha , zp-3-alpha , zp3-alpha sperm-binding glycoprotein , RC55 , zona pellucida glycoprotein X , zona pellucida glycoprotein ZP-X

GENE ID SPECIES
394364 Xenopus laevis
394445 Xenopus (Silurana) tropicalis
395692 Gallus gallus
442977 Canis lupus familiaris
469721 Pan troglodytes
709637 Macaca mulatta
779327 Xenopus laevis
100134840 Meleagris gallopavo
100406555 Callithrix jacchus
57829 Homo sapiens
282833 Rattus norvegicus
280965 Bos taurus
493791 Felis catus
397111 Sus scrofa
100009131 Oryctolagus cuniculus
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