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ACTN encodes a member of the alpha-actin binding protein gene family.
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There was no statistically significant association between angiotensin-converting enzyme (show ACE ELISA Kits) or alpha-actinin-3 (show ACTN3 ELISA Kits) polymorphisms and the presence of adolescent idiopathic scoliosis in females.
Study suggests that ACTN3 R577X polymorphism is associated with non-acute ankle sprain in the Chinese Han population.
X-allele triathletes in the ACTN3 (show ACTN3 ELISA Kits) R577X polymorphism presented greater signs of exercise-induced muscle damage during a half-ironman race than RR homozygotes.
Studied the association between the ACTN3 (show ACTN3 ELISA Kits) R577X genotype and elite athlete status in a large Asian (Japanese) cohort of track and field athletes. 003). A significant linear correlation was found between the RR + RX genotype and athlete status.
the influence of ACTN3 (show ACTN3 ELISA Kits) genotypes on the cost of locomotion was investigated.
Most studies assessing healthy adults demonstrated that 577RX heterozygotes performed intermediately and/or similarly to the RR genotypes. Other studies showed no definitive genetic model with ACTN3 (show ACTN3 ELISA Kits) null allele heterozygosity on muscle performance. [review]
Findings indicate that the IGF2 ApaI polymorphism, but not the ACTN3 (show ACTN3 ELISA Kits) R577X polymorphism, may be a candidate gene associated with some types of muscle strength and judo status.
There may be a relationship between the ACTN3 (show ACTN3 ELISA Kits) genotype and HDL (show HSD11B1 ELISA Kits)-C and adiponectin (show ADIPOQ ELISA Kits) levels in rugby players.
Actn3 (show ACTN3 ELISA Kits) controls sarcomeric composition and muscle function in a dose-dependent fashion.
the ACE (show ACE ELISA Kits) I/D and ACTN3 (show ACTN3 ELISA Kits) R577X (rs1815739) genetic variants in elite rugby athletes (rugby union and league) and genotype frequencies to controls and between playing positions, is reported.
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.
F-actin cross-linking protein
, alpha-actinin skeletal muscle