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beta-Site APP-Cleaving Enzyme 1 (BACE) ELISA Kits

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Additionally we are shipping beta-Site APP-Cleaving Enzyme 1 Antibodies (204) and beta-Site APP-Cleaving Enzyme 1 Proteins (33) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BACE 23821 P56818
BACE 29392 P56819
BACE 23621 P56817
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Top beta-Site APP-Cleaving Enzyme 1 ELISA Kits at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.78 pg/mL 3.12-200 pg/mL   96 Tests Log in to see 9 to 11 Days
$1,026.67
Details
Rat 0.062 ng/mL 15.63-1000 pg/mL 96 Tests Log in to see 9 to 11 Days
$720.00
Details
Mouse 7.0 pg/mL 31.25-2000 pg/mL 96 Tests Log in to see 9 to 11 Days
$682.11
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
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Pig
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$770.00
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Monkey
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$770.00
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Guinea Pig
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$770.00
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Rabbit
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$770.00
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Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
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Goat
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$801.43
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Top referenced beta-Site APP-Cleaving Enzyme 1 ELISA Kits

  1. Human BACE ELISA Kit for Sandwich ELISA - ABIN365021 : Qian, Ding, Cheng, Zhu, Zhao, Jin, Guan, Zhang, Chen, Xu: Early biomarkers for post-stroke cognitive impairment. in Journal of neurology 2012 (PubMed)

More ELISA Kits for beta-Site APP-Cleaving Enzyme 1 Interaction Partners

Mouse (Murine) beta-Site APP-Cleaving Enzyme 1 (BACE) interaction partners

  1. reveal Dicer1 (show DICER1 ELISA Kits)-miR (show MLXIP ELISA Kits)-328-Bace1 signalling as a determinant of brown adipose tissue function

  2. The present findings are consistent with our previous behavioral data showing that BACE1 haploinsufficiency rescues memory deficits in 5XFAD mice irrespective of sex but only in the younger age group.

  3. p38alpha (show MAPK14 ELISA Kits) MAPK (show MAPK1 ELISA Kits) plays a critical role in the regulation of BACE1 degradation and Abeta (show APP ELISA Kits) generation in Alzheimer Disease pathogenesis

  4. Swedish mutant APP (show APP ELISA Kits)-based BACE1 binding site peptide reduces APP (show APP ELISA Kits) beta-cleavage and cerebral Abeta (show APP ELISA Kits) levels in Alzheimer's mice.

  5. evidence that HFD, by regulation of subcellular trafficking of BACE1, promotes APP (show APP ELISA Kits) cleavage.

  6. Traumatic brain injury-induced BACE1 up-regulation is significantly suppressed in brain with deficient N-acetylyglucosaminyltransferase-III.

  7. results indicate that NFAT (show NFATC1 ELISA Kits) is a BACE1 transcription factor. Our study suggests that inhibition of NFAT (show NFATC1 ELISA Kits)-mediated BACE1 expression may be a valuable drug target for AD therapy

  8. The results of this study concluded that stimulus-dependent neuronal activity can control the expression of the RA catabolic enzyme Cyp26B1 (show CYP26B1 ELISA Kits) and downstream genes such as BACE1.

  9. MicroRNA-29c targets BACE1 and has a neuroprotective role in vitro and in vivo.

  10. BACE1 and ADAM10 (show ADAM10 ELISA Kits) are in close proximity in hippocampal neuron synaptic vesicles.

Human beta-Site APP-Cleaving Enzyme 1 (BACE) interaction partners

  1. GG genotype and G allele of BACE1 gene rs638405 probably increase the risk of AD. [META-ANALYSIS]

  2. study reports that sAbetaPPalpha, the product of the cleavage of AbetaPP by alpha-secretase, is a potent endogenous direct inhibitor of the BACE enzyme, and that its inhibition is likely by an allosteric mechanism

  3. p38alpha (show MAPK14 ELISA Kits) MAPK (show MAPK1 ELISA Kits) plays a critical role in the regulation of BACE1 degradation and Abeta (show APP ELISA Kits) generation in Alzheimer Disease pathogenesis

  4. this is the first study to acquire a DNA aptamer that exhibited binding specificity to BACE1 and inhibited its activity.

  5. Results reveal a link between p25 (show LCN2 ELISA Kits) and BACE1 in Alzheimer disease (AD) brains and suggest that upregulated Cdk5 (show CDK5 ELISA Kits) activation by p25 (show LCN2 ELISA Kits) accelerates AD pathogenesis by enhancing BACE1 activity via phosphorylation.

  6. the Alzheimer's disease-protective 'Icelandic' mutation greatly attenuates APP (show APP ELISA Kits)-BACE-1 interactions, suggesting a mechanistic basis for protection.

  7. Studies suggest that beta-Secretases BACE1/2 plays an important role in retinal homeostasis and that BACE upregulation in response to stress is a protective measure.

  8. analysis of the differential dose-dependent effects of simvastatin on HIF-1alpha (show HIF1A ELISA Kits) and BACE in cultured Alzheimer's disease cybrid cells

  9. CHIP stabilizes amyloid precursor protein (show APP ELISA Kits) via proteasomal degradation and p53 (show TP53 ELISA Kits)-mediated trans-repression of BACE1.

  10. BACE1 elevation in the endothelia and perivascular neurites may be involved in angiopathic Abeta (show APP ELISA Kits) deposition, while BACE1 elevation in meningeal cells might contribute Abeta (show APP ELISA Kits) to leptomeningeal amyloidosis.

Zebrafish beta-Site APP-Cleaving Enzyme 1 (BACE) interaction partners

  1. bace1 mutants display hypomyelination in the peripheral nervous system and supernumerary neuromasts while in bace2 (show BACE2 ELISA Kits) mutants the shape and migration of melanocytes is affected.

beta-Site APP-Cleaving Enzyme 1 (BACE) Antigen Profile

Antigen Summary

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with BACE

  • beta-site APP-cleaving enzyme 1 (BACE1) antibody
  • beta-site APP-cleaving enzyme 1 (MGC145931) antibody
  • beta-site APP-cleaving enzyme 1 (LOC100232107) antibody
  • beta-site APP-cleaving enzyme 2 (bace2) antibody
  • beta-site APP-cleaving enzyme 2 (BACE2) antibody
  • beta-site APP-cleaving enzyme 2 (LOC100224177) antibody
  • beta-site APP cleaving enzyme 1 (Bace1) antibody
  • beta-site APP-cleaving enzyme 1 (bace1) antibody
  • ASP2 antibody
  • BACE antibody
  • BACE1 antibody
  • BACE2 antibody
  • C76936 antibody
  • HSPC104 antibody
  • MGC68482 antibody
  • MGC68881 antibody
  • MGC145931 antibody
  • zgc:77409 antibody

Protein level used designations for BACE

beta-site APP-cleaving enzyme 1 , beta-secretase 1 , beta-secretase 1 isoform A preproprotein , beta-secretase 1 isoform B preproprotein , beta-secretase 1 isoform C preproprotein , beta-secretase 1-like , beta-site APP-cleaving enzyme 2 , beta-secretase 2-like , APP beta-secretase , ASP2 , asp 2 , aspartyl protease 2 , beta-site amyloid precursor protein cleaving enzyme 1 , memapsin-2 , membrane-associated aspartic protease 2 , beta-secretase 1 precursor variant 1 , beta-site APP cleaving enzyme 1 , beta-site amyloid beta A4 precursor protein-cleaving enzyme , transmembrane aspartic proteinase Asp2 , beta-site APP cleaving enzyme , beta secretase 1

GENE ID SPECIES
100071137 Equus caballus
451573 Pan troglodytes
697694 Macaca mulatta
779940 Xenopus (Silurana) tropicalis
100025518 Monodelphis domestica
100232107 Taeniopygia guttata
100459804 Pongo abelii
380307 Xenopus laevis
398806 Xenopus laevis
747819 Pan troglodytes
100016587 Monodelphis domestica
100216145 Xenopus (Silurana) tropicalis
100224177 Taeniopygia guttata
100406072 Callithrix jacchus
100602656 Nomascus leucogenys
23821 Mus musculus
29392 Rattus norvegicus
100135485 Cavia porcellus
23621 Homo sapiens
614333 Bos taurus
403005 Danio rerio
419768 Gallus gallus
489390 Canis lupus familiaris
100511707 Sus scrofa
100343442 Oryctolagus cuniculus
101119667 Ovis aries
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