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anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) Antibodies

Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Additionally we are shipping erythrocyte Membrane Protein Band 4.9 (Dematin) Kits (5) and erythrocyte Membrane Protein Band 4.9 (Dematin) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EPB49 2039 Q08495
EPB49 13829 Q9WV69
EPB49 361069  
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Top anti-erythrocyte Membrane Protein Band 4.9 (Dematin) Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Dematin  Antibody  in Y79 cell line lysates (35ug/lane). This demonstrates the Dematin antibody detected the Dematin protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells treated with Insulin 0.01U/ml 15', using Dematin (Phospho-Ser403) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using Dematin (Phospho-Ser403) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from 293 cells, using Dematin (Ab-403) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Dematin (Ab-403) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB EPB49 Antibody (Center)  western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the EPB49 antibody detected the EPB49 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB AP20222PU-N Dematin antibody staining of Paraffin-Embedded Human heart tissue by Immunohistochemistry. Western blot analysis using AP20222PU-N Dematin antibody in extracts from 293 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Anti-DMT1/Dematin Polyclonal Antibody, Unconjugated (ABIN701065) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 14 Days
$201.19
Details

EPB49 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-erythrocyte Membrane Protein Band 4.9 (Dematin) Antibodies

  1. Human Polyclonal EPB49 Primary Antibody for EIA, WB - ABIN951882 : Vugmeyster, Ostrovsky, Li: Comparison of fast backbone dynamics at amide nitrogen and carbonyl sites in dematin headpiece C-terminal domain and its S74E mutant. in Journal of biomolecular NMR 2010 (PubMed)
    Show all 5 references for ABIN951882

More Antibodies against erythrocyte Membrane Protein Band 4.9 (Dematin) Interaction Partners

Human erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) interaction partners

  1. When unphosphorylated, dematin's two F-actin binding domains move independent of one another permitting them to bind different F-actin filaments.

  2. the headpiece domain of dematin regulates calcium mobilization and signaling in platelets

  3. a novel functional role for dematin in regulating erythrocyte membrane function.

  4. Fast backbone dynamics probed at amide nitrogen versus carbonyl carbon sites for dematin headpiece C-terminal. The reduction of mobility in the loop region upon the S74E mutation can be seen from the (15)N order parameters.

  5. results suggest that phosphorylation of the dematin headpiece acts as a conformational switch within this headpiece domain

  6. a crucial role for this proline residue in structural stability and folding potential of HP (sub)domains consistent with Pro-Trp (show TBPL1 Antibodies) stacking as a more general determinant of protein stability

  7. study investigated motions in the backbone of dematin headpiece domain and its mutant DHPS74E using several complementary NMR relaxation techniques

  8. results suggest that the core domain of dematin exhibits properties typical of a natively unfolded protein, while the headpiece domain is folded in a conformation essentially identical to its native structure

Mouse (Murine) erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) interaction partners

  1. the headpiece domain of dematin regulates calcium mobilization and signaling in platelets

  2. remodeling of the host cell directed Plasmodium includes the recruitment of dematin, an actin-binding protein (show PFN1 Antibodies) of the erythrocyte membrane skeleton and its repositioning to the parasite

  3. physiological significance of dematin and demonstrate a role for the headpiece domain in the maintenance of structural integrity and mechanical properties of erythrocytes in vivo.

  4. Dematin plays an essential role in the maintenance of erythrocyte shape and membrane stability; dematin-membrane interaction could link the junctional complex to the plasma membrane in erythroid cells.

  5. Dematin is expressed in skin, mostly in dermal fibroblasts and hypodermal adipocytes. Knockout mice lacking dematin exhibit hair loss.

  6. These results unveil a new function of dematin as a negative regulator of the RhoA (show RHOA Antibodies) activation pathway with physiological implications for normal and pathogenic signaling pathways.

erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) Antigen Profile

Protein Summary

Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993

Gene names and symbols associated with EPB49

  • erythrocyte membrane protein band 4.9 (dematin) (epb49) antibody
  • erythrocyte membrane protein band 4.9 (dematin) (EPB49) antibody
  • erythrocyte membrane protein band 4.9 (dematin) (DMTN) antibody
  • erythrocyte membrane protein band 4.9 (LOC100357787) antibody
  • dematin actin binding protein (DMTN) antibody
  • dematin actin binding protein (Dmtn) antibody
  • AI325486 antibody
  • dematin antibody
  • DMT antibody
  • Epb4.9 antibody
  • Epb49 antibody
  • MGC80597 antibody
  • MGC108072 antibody

Protein level used designations for EPB49

erythrocyte membrane protein band 4.9 (dematin) , dematin , dematin actin-binding protein , erythrocyte membrane protein band 4.9 , erythrocyte protein band 4.9

GENE ID SPECIES
444150 Xenopus laevis
486132 Canis lupus familiaris
548579 Xenopus (Silurana) tropicalis
706762 Macaca mulatta
741796 Pan troglodytes
100030483 Monodelphis domestica
100056495 Equus caballus
100173938 Pongo abelii
100357787 Oryctolagus cuniculus
100592471 Nomascus leucogenys
2039 Homo sapiens
13829 Mus musculus
361069 Rattus norvegicus
512981 Bos taurus
Selected quality suppliers for anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) Antibodies
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