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gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 Proteins (GABRA4)

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA4 Antibodies (119) and GABRA4 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GABRA4 GABRA4 140675 P28471
GABRA4 2557 P48169
GABRA4 14397 Q9D6F4
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Top GABRA4 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

GABRA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
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Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) interaction partners

  1. GABRA4 is associated with autism spectrum disorder in a dataset from Argentina.

  2. Transgenic mice with the alpha4betadelta GABAA (show GABRg1 Proteins) receptor subunit deletion show increased conditioned place preference, but not from delta-deficient or alpha4-deficient knockout mice.

  3. The pathway by which GABRA2 initially confers risk for eventual alcohol problems begins with a predisposition to sensation-seeking early in adolescence.

  4. Association between premenstrual symptom severity and two genes from the gamma-aminobutyric acid (GABA) pathway: steroid-5-alpha-reductase, alpha polypeptide (show ITGAE Proteins) 1 (SRD5A1 (show SRD5A1 Proteins)) and gamma-aminobutyric acid receptor subunit alpha-4 (GABRA4).

  5. single nucleotide polymorphisms studied in the GABRA4, GABRE (show GABRE Proteins), and GABRQ (show GABRQ Proteins) genes are not related to the risk for familial ET.

  6. GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1.

  7. These results confirmed our earlier findings, indicating GABRA4 and GABRB1 as genes contributing to autism susceptibility, extending the effect to multiple ethnic groups and suggesting seizures as a stratifying phenotype.

  8. Lower delta mRNA levels in schizophrenia might reflect a reduced number of alpha(1)beta(x)delta (show DLL1 Proteins) GABA(A) receptors that could contribute to deficient tonic inhibition and prefrontal cortical dysfunction in schizophrenia.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) interaction partners

  1. This study addressed the effects of AW on changes in the expression of Gabra4 and related genes that encode other subunits of GABAARs

  2. GABAA (show GABRg1 Proteins) receptors in the mediodorsal thalamic nucleus (MD) modulate fear extinction.

  3. Increase in GABRA4 activity promotes hippocampal neurogenesis via nuclear factor of activated T cell (show NFATC3 Proteins) (NFATc)4 (show NFATC4 Proteins).

  4. This study demonistrated that alpha4-GABAARs contribute to nRT burst-mediated inhibition and that activity-dependent recruitment of eGABAARs dynamically influences the ventrobasal neuron tonic conductance during nRT tonic spike trains.

  5. Data suggest that the availability of distinct GABA(A) R subtypes (Gabra2, -4, and Gabrd) provides a molecular mechanism endowing spatiotemporal specificity to GABAergic control of neuronal maturation in adult brain.

  6. alpha-4 subunit of the GABAA (show GABRg1 Proteins) receptor is transcriptionally regulated

GABRA4 Protein Profile

Protein Summary

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Gene names and symbols associated with GABRA4

  • gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 4 (Gabra4)
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 (Gabra4)
  • Gabra-4 protein
  • GABRA4 protein

Protein level used designations for GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4 , gamma-aminobutyric acid A receptor, alpha 4 , GABA(A) receptor subunit alpha-4 , gamma-aminobutyric acid receptor subunit alpha-4-like , GABA-A receptor alpha-4 subunit , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4 , gamma-aminobutyric acid receptor subunit alpha-4 , GABA(A) receptor, alpha 4

GENE ID SPECIES
422770 Gallus gallus
471392 Pan troglodytes
482132 Canis lupus familiaris
704008 Macaca mulatta
100339882 Oryctolagus cuniculus
100400491 Callithrix jacchus
100465826 Ailuropoda melanoleuca
100546032 Meleagris gallopavo
100592841 Nomascus leucogenys
140675 Rattus norvegicus
2557 Homo sapiens
282238 Bos taurus
14397 Mus musculus
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