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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA3 Antibodies (69) and GABRA3 Kits (4) and many more products for this protein.
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Gabra3 activates the AKT (show AKT1 Proteins) pathway to promote breast cancer cell migration, invasion and metastasis. The A-to-I RNA-edited form of Gabra3 is found only in non-invasive breast cancers. Edited Gabra3 suppresses breast cancer cell invasion and metastasis.
The N-terminal region of GABRA3 and the GlyR beta subunit (show POLG Proteins) occupies the same binding site of gephyrin (show GPHN Proteins).
high expression of GABBR2 (show GABBR2 Proteins) with a low expression of GABR(A3) may predict a better outcome in non-small cell lung cancer
A novel role for GA-repeat core promoter to regulate gene expression in the genes such as GABRA3 involved in development and evolution.
We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA (show GABRg1 Proteins)) receptor subunit-encoding genes, GABRQ (show GABRQ Proteins) and GABRA3.this is the first report of ASD (show ARSD Proteins) patients with truncating mutations in GABA receptors genes.
The results indicate that there may be specific GABA receptor gene expression variation in migraine, particularly involving the GABRA3 and GABBR2 (show GABBR2 Proteins) genes.
The ratios of beta(3)/beta(2) and alpha(5)/alpha(1) subunit protein expression in Angelman syndrome (show ube3a Proteins) cortex were significantly decreased when compared with controls.
GABRA3 gene was overexpressed in lung cancer and rarely expressed in other cancers
These findings suggest that common variation in the GABRA2 (show GABRA2 Proteins), GABRA3, GABRA6 (show GABRA6 Proteins), and GABRG2 (show GABRG2 Proteins) genes does not play a major role in liability to anxiety spectrum disorders.
The results of our study indicate that GABRA 3 gene might also be involved in the genetic pathophysiology of unipolar major depressive disorder
Absence of the Gabra3 receptor subunit slows recovery from ethanol-induced incoordination.
Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice
Despite the exclusive expression of alpha3-containing GABAA (show GABRg1 Proteins) receptors in the reticular thalamic nucleus, these receptors do not seem to be critical for the mediation of the effects of diazepam on the sleep EEG
editing of the Gabra-3 mRNA is important for normal brain development.The extent of editing is low at birth but increases with age, reaching close to 100% in the adult brain.
The phenotypes following global deletion of the GABAA (show GABRg1 Proteins) receptor alpha3 subunit provided relevant insights into the potential behavioural relevance of this specific receptor subtypes in the modulation of both affective and cognitive functions.
Deletion of the GABAAR (show GABRG2 Proteins) alpha3 subunit reduces evoked thalamic oscillatory activity.
Resutls show that the variation in editing gave receptors like HTR2C (show HTR2C Proteins) and GABA(A) (gamma-aminobutyric acid type A) a different set of protein isoforms during development from those in the adult animal.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
gamma-aminobutyric acid (GABA) A receptor, alpha 3
, gamma-aminobutyric acid A receptor, alpha 3
, gamma-aminobutyric acid A receptor, alpha 3-like
, gamma-aminobutyric acid receptor subunit alpha-3-like
, GABA(A) receptor subunit alpha-3
, GABA(A) receptor, alpha 3
, gamma-aminobutyric acid receptor subunit alpha-3
, gamma-animobutyric acid (GABA) A receptor, alpha 3
, GABA-A receptor alpha-3 subunit
, Gamma-animobutyric acid (GABA) A receptor alpha 3
, Gamma-animobutyric acid (GABA) A receptor, alpha 3
, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3
, gamma-aminobutyric acid receptor, subunit alpha 3