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PRPS2 encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. Additionally we are shipping PRPS2 Proteins (10) and PRPS2 Kits (5) and many more products for this protein.
Showing 10 out of 53 products:
Human Polyclonal PRPS2 Primary Antibody for EIA, WB - ABIN954329
Mannava, Grachtchouk, Wheeler, Im, Zhuang, Slavina, Mathews, Shewach, Nikiforov: Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells. in Cell cycle (Georgetown, Tex.) 2008
Show all 5 references for ABIN954329
Dog (Canine) Polyclonal PRPS2 Primary Antibody for IHC, WB - ABIN2776822
Ishijima, Asai, Kita, Sonoda, Tatibana et al.: Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of ... in Biochimica et biophysica acta 1997
Chicken Polyclonal PRPS2 Primary Antibody for WB - ABIN2776821
Iizasa: [Increased activity of PRPP synthetase]. in Nihon rinsho. Japanese journal of clinical medicine 2008
PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 (show TPM4 Antibodies) Sertoli cells via the p53 (show TP53 Antibodies)/Bcl-2 (show BCL2 Antibodies)/caspases signaling pathway.
Meta-analysis of genome-wide association studies identifies a novel variant in PRPS2 on Xp22.3 as susceptibility locus for systemic lupus erythematosus.
The expression of different genes encoding subunits of PRPS (show MSMB Antibodies) enzyme is affected by hypoxia in tumor glioma cells, but the effect of hypoxia is modified by suppression of endoplasmic reticulum stress signaling enzyme ERN1 (show ERN1 Antibodies).
Analysis of in vivo C-MYC (show MYC Antibodies) interactions with TS, IMPDH2 (show IMPDH2 Antibodies) and PRPS2 genes confirmed that they are direct C-MYC (show MYC Antibodies) targets.
Study demonstrates with a Prps2 knockout mouse that the nexus between protein and nucleotide biosynthesis controlled by PRPS2 is crucial for Myc (show MYC Antibodies)-driven tumorigenesis.
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
, Phophoribosylpyrophosphate synthetase, subunit II
, phosphoribosyl pyrophosphate synthase II
, phosphoribosyl pyrophosphate synthetase II
, ribose-phosphate pyrophosphokinase 2
, PPRibP synthetase
, ribose-phosphate diphosphokinase 2